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61,005 resultsShowing papers similar to Progress in understanding the impact of microplastics on respiratory allergic diseases
ClearEffects of microplastics on allergic airways and potential pathogenesis: a review
This review examines how microplastics, which can enter the body through breathing, eating, and skin contact, may affect allergic airway conditions. Researchers found evidence that microplastics can damage airway lining cells, disrupt the protective barrier of the respiratory tract, and trigger heightened airway reactivity. The study suggests that chronic microplastic exposure may worsen allergic airway inflammation, though more research is needed to fully understand the mechanisms involved.
Microplastics in Allergic Rhinitis: Multimechanistic Drivers of Barrier Disruption and Immune Dysregulation
This review examines the multimechanistic pathways by which microplastics drive barrier disruption and immune dysregulation in allergic rhinitis, considering how physical and chemical properties of microplastic particles interact with nasal epithelial and immune function. The paper synthesizes emerging evidence on microplastics as a novel contributor to upper airway allergic disease.
Airway exposure to microplastics: Potential mechanisms from epithelial barrier damage to the development of allergic rhinitis
This review summarized the mechanisms by which airborne microplastic exposure triggers allergic rhinitis, identifying pathways including physical and chemical disruption of the airway epithelial barrier, oxidative stress from adsorbed pollutants, and induction of Th2 immune responses and IgE class-switching. The findings support airborne MPs as a novel trigger for upper respiratory allergic disease.
Cellular and molecular mechanisms of allergic asthma
Researchers reviewed the cellular and molecular mechanisms behind allergic asthma, finding that rising exposure to environmental pollutants — including microplastics — likely contributes to the disease's increasing prevalence, as pollutants disrupt airway barrier integrity and trigger immune responses that lead to chronic airway inflammation.
Airborne microplastics: Consequences to human health?
Researchers reviewed existing evidence on airborne microplastics and their potential effects on human respiratory health. Studies of workers exposed to plastic fibers and particles have documented airway inflammation and breathing difficulties, suggesting that susceptible individuals may face health risks even from environmental concentrations. The paper calls for greater awareness and future research into the health consequences of inhaling microplastic particles.
Airborne micro- and nanoplastics: emerging causes of respiratory diseases
This review examines growing evidence that tiny airborne plastic particles can enter the lungs and trigger or worsen respiratory diseases including asthma, chronic obstructive pulmonary disease, and lung inflammation. The smallest nanoplastics are especially concerning because they can penetrate deep into lung tissue and even enter the bloodstream, yet research on airborne plastic health effects significantly lags behind studies on waterborne exposure.
The Impact of Microplastics on Allergy: Current Status and Future Research Directions
This study reviews current evidence on how microplastics may influence allergic responses, noting that microplastics can compromise epithelial barriers and promote type 2 inflammation associated with allergies. The authors emphasize an urgent need for research into dose-dependent immunotoxicological mechanisms to better understand the relationship between microplastic exposure and allergy development. The study calls for evidence-based policies to reduce microplastic exposure and its potential contribution to the growing allergy burden.
Respiratory Toxicity of Microplastics: Mechanisms, Clinical Outcomes, and Future Threats
This review examined the mechanisms by which inhaled airborne microplastics cause respiratory harm, including inflammation, oxidative stress, fibrosis, and impaired mucociliary clearance. The authors also discuss emerging evidence linking microplastic inhalation to worsening asthma, COPD, and potentially lung cancer.
Breathing plastics: Influence of airborne microplastics on the respiratory microbiome and health of human lungs (Review)
Researchers reviewed evidence showing that inhaled airborne microplastics can physically interact with the microbial community living in human lungs, disrupting its balance and triggering inflammation linked to conditions like asthma and fibrosis. Because microplastic particles have been found in lung tissue and fluid samples, inhalation is now recognized as a significant exposure route with measurable consequences for respiratory health.
Silent invaders: the role of MPs on epithelium inflammation and damage in airway diseases
This review examines how inhaled microplastics and nanoplastics interact with airway epithelial surfaces and trigger inflammatory, oxidative, and structural changes that may contribute to respiratory diseases. The study describes how these particles activate key inflammatory pathways such as NF-kB and PI3K/Akt/mTOR, potentially worsening conditions like asthma and COPD through enhanced barrier dysfunction, oxidative stress, and disrupted tissue repair.
Human Responsive Biomarkers of Airborne Microplastics Exposure: Evaluation and Analysis for Health and Environment
This research review looked at 14 studies to understand how tiny plastic particles in the air affect human health by measuring specific markers in our blood and lungs. The studies found that breathing in microplastics causes inflammation in our airways and lungs, similar to what happens with asthma, by triggering the body's immune response. This matters because it helps scientists develop better ways to detect early health problems from plastic pollution and create guidelines to protect people from these invisible particles we breathe every day.
Preliminary Study of Microplastic in Allergic Rhinitis
Researchers compared microplastic concentrations in the nasal cavities of patients with allergic rhinitis versus healthy individuals. They found significantly higher levels of microplastics in the noses of people with the allergic condition. This preliminary finding suggests a potential connection between microplastic exposure in the nasal passages and allergic airway conditions, though more research is needed to understand the relationship.
Detection of microplastics in patients with allergic rhinitis
In a study of 66 patients, researchers found significantly more microplastic particles in nasal wash samples from people with allergic rhinitis compared to healthy volunteers. The microplastics found were mostly fibers and fragments small enough to deposit in nasal passages during normal breathing. This is among the first studies to link airborne microplastic exposure in the nose to an allergic condition, suggesting inhaled microplastics may contribute to nasal inflammation.
Confronting allergies: strategies for combating pollution and safeguarding our health
This review examined the growing body of evidence linking environmental pollutants, including airborne microplastics, to increasing rates of allergic reactions worldwide. Researchers found that air pollution and indoor contaminants can worsen respiratory allergies, while climate change intensifies seasonal allergy patterns. The study emphasizes the need for comprehensive action including government regulation and public awareness to reduce pollution-driven allergy risks.
Airborne Microplastics: Another Threatening to Our Health
This review examines the emerging evidence on airborne microplastics, covering their sources, how they travel through the atmosphere, and how they enter the human respiratory system through inhalation. Researchers highlight potential health effects including pulmonary inflammation, oxidative stress, and endocrine disruption, with particle size influencing how deeply they penetrate into the lungs. The study calls for standardized measurement protocols and urgent interdisciplinary research to better understand the health risks of breathing in microplastic particles.
An emerging class of air pollutants: Potential effects of microplastics to respiratory human health?
This review explores the emerging concern that airborne microplastics can be inhaled by humans, potentially causing adverse effects on the respiratory system. Researchers compiled available data on the concentration, size, shape, and chemical composition of microplastic particles found in urban air. The findings suggest that airborne plastic debris represents a largely understudied class of air pollutant with potential implications for human health.
Airborne microplastics: a Trojan horse for respiratory dysfunction and multiorgan damage
This review examined evidence on airborne microplastics as a route of human exposure, focusing on how inhaled particles may affect respiratory function and potentially reach other organs. The study suggests that microplastics can act as carriers for other pollutants and pathogens, and that inhalation exposure warrants greater research attention alongside the more commonly studied ingestion pathway.
Effect of Microplastic Inhalation on Allergic and Nonallergic Rhinitis
Researchers analyzed nasal lavage samples from rhinitis patients and healthy controls, finding significantly higher microplastic concentrations in both allergic and nonallergic rhinitis groups compared to controls. Younger participants and those with more severe symptoms tended to have higher microplastic levels in their nasal passages. The study suggests that inhaled microplastics may play a role in nasal inflammation, though more research is needed to establish a direct cause-and-effect relationship.
The Effects of Microplastics and Nanoplastics in the Nasal Airway and Upper Respiratory Tract
This review examines the effects of airborne microplastics on the upper respiratory tract and nasal region, an area largely overlooked despite being the initial point of contact with inhaled particles. The literature collectively indicates that microplastics may cause changes in cell morphology, cytotoxicity, and inflammatory effects in nasal tissues, with potential impacts on patient quality of life.
Airborne microplastics: A narrative review of potential effects on the human respiratory system
This review consolidates research on airborne microplastics and their potential effects on the human respiratory system. Studies show that inhaled microplastics can deposit in the lungs, trigger inflammation, cause oxidative stress, and lead to cell damage and death. While human exposure evidence is still limited, animal and cell studies suggest that long-term inhalation of airborne microplastics could pose significant risks to lung health.
Airborne microplastics and their impact on human health: A critical review
This review analyzes the growing body of research on microplastics floating in indoor and outdoor air and their potential effects on human health. Evidence indicates that inhaled microplastics can trigger inflammatory responses and cellular damage in the lungs, liver, and reproductive system, and may carry toxic additives deeper into the body. The authors call for more interdisciplinary research to understand the long-term health implications of breathing in these tiny plastic particles.
Microplastics as environmental modifiers of lung disease
This review examines growing evidence that inhaled microplastics may contribute to lung diseases including asthma, pulmonary fibrosis, and chronic obstructive pulmonary disease. Researchers found that different plastic types, sizes, and weathering states can trigger inflammation, oxidative stress, and cellular changes in lung tissue, suggesting microplastics may act as environmental modifiers that worsen respiratory conditions.
Impact of Common Environmental Exposures on Airway Cilia Biology: Insights into Structure, Function, and Signaling Mechanisms.
This review examined how daily environmental exposures—including cigarette smoke, fine particulate matter, allergens, and microplastics—impair the structure and function of airway cilia, which are essential for clearing inhaled pathogens from the lungs. The authors found that microplastics can physically disrupt cilia and trigger inflammatory signaling, contributing to the progression of respiratory diseases.
Detrimental effects of microplastic exposure on normal and asthmatic pulmonary physiology
Researchers exposed both healthy and asthmatic mice to airborne microplastics and found significant lung inflammation, immune activation, and increased mucus production in both groups. Microplastic particles were taken up by immune cells called macrophages, and gene analysis revealed changes in immune response, cellular stress, and cell death pathways. The study suggests that inhaling microplastics may worsen respiratory health in both normal and vulnerable populations.