Papers

61,005 results
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Article Tier 2

Enzymatic PET Degradation

This review examines enzymatic degradation of PET (polyethylene terephthalate), the plastic used in bottles and polyester clothing, as a promising pathway for breaking down this persistent polymer. Advances in engineering more efficient PET-degrading enzymes could enable industrial-scale biological recycling and reduce the environmental accumulation of PET microplastics.

2019 CHIMIA International Journal for Chemistry 50 citations
Article Tier 2

Current Knowledge on Polyethylene Terephthalate Degradation by Genetically Modified Microorganisms

This review covers genetically modified microorganisms engineered to degrade polyethylene terephthalate, examining how bioengineering of enzymes such as PETase and enhanced expression systems can overcome the low biodegradation rates of wild-type microorganisms toward this ubiquitous plastic.

2021 Frontiers in Bioengineering and Biotechnology 92 citations
Article Tier 2

Microbial engineering strategies for synthetic microplastics clean up: A review on recent approaches

This review examined microbial engineering strategies for breaking down synthetic microplastics, covering PETase and MHETase enzyme engineering, immobilization approaches, and the major challenges that remain before biological plastic cleanup can be deployed at scale.

2022 Environmental Toxicology and Pharmacology 36 citations
Article Tier 2

Microbial enzymes for the recycling of recalcitrant petroleum‐based plastics: how far are we?

This review examines the progress in identifying microbial enzymes capable of breaking down petroleum-based plastics like polyethylene, polystyrene, polyurethane, and PET. Researchers highlight recent advances in using polyester-degrading enzymes to recover raw materials from PET waste through biocatalytic recycling. The study discusses the potential and remaining challenges of using biological approaches to address the growing global problem of plastic waste accumulation.

2017 Microbial Biotechnology 788 citations
Article Tier 2

Biodegradation of Microplastic: A Sustainable Approach

This review examines biological approaches to microplastic degradation, covering microorganisms and enzymes capable of breaking down common plastic polymers such as PET and polyethylene. Biodegradation could offer a sustainable path to reducing microplastic accumulation in soil, water, and marine environments.

2023 International Journal of Current Microbiology and Applied Sciences
Article Tier 2

Enzymatic Remediation of Polyethylene Terephthalate (PET)–Based Polymers for Effective Management of Plastic Wastes: An Overview

Enzymatic approaches for remediating PET-based plastic waste were reviewed, covering PETase and related enzymes that can break PET into reusable monomers. Enzyme engineering strategies to improve thermostability and catalytic efficiency are discussed as a pathway to scalable biological PET recycling.

2020 Frontiers in Bioengineering and Biotechnology 193 citations
Article Tier 2

Biodegradation of Plastic and the Role of Microbial Enzymes in Plastic Waste Management

This review examines how microbial enzymes, particularly PET hydrolases and oxidative enzymes, can depolymerize and break down common plastic polymers through biological degradation. The study suggests that enzymatic approaches to plastic waste management offer a promising complement to mechanical and chemical recycling, though optimizing enzyme activity and scaling up the process remain key challenges.

2026 International Journal of Education Management and Technology
Article Tier 2

Engineered polyethylene terephthalate hydrolases: perspectives and limits

This review examines progress in engineering enzymes that can break down PET plastic, the material used in most beverage bottles and synthetic textiles. Researchers found that while significant advances have been made through protein engineering and machine learning, no enzyme yet exists that can efficiently degrade the crystalline form of PET found in real-world waste. The study outlines the key challenges remaining before enzymatic plastic recycling can work at industrial scale, including handling microplastic contamination.

2024 Applied Microbiology and Biotechnology 27 citations
Article Tier 2

Microbial Degradation of (Micro)plastics: Mechanisms, Enhancements, and Future Directions

This review examines how microorganisms can break down microplastics using enzymes like PETase and laccases, offering a more environmentally friendly alternative to other cleanup methods. While microbial degradation holds promise for reducing microplastic pollution and its associated health risks, current efficiency is too low for large-scale application and needs further improvement.

2024 Fermentation 54 citations
Article Tier 2

Biodegradation of Poly(Ethylene Terephthalate) Microplastics by Baceterial Communities From Activated Sludge

Scientists isolated bacteria from wastewater treatment sludge that can biodegrade PET plastic, used in plastic bottles and food packaging. The bacteria broke down PET microplastics over a 60-day period, pointing toward a potential biological tool for removing plastic contamination from water treatment systems.

2021
Article Tier 2

Biodegradation of Poly(Ethylene Terephthalate) Microplastics by Baceterial Communities From Activated Sludge

Scientists isolated bacteria from wastewater treatment sludge that can biodegrade PET plastic, used in plastic bottles and food packaging. The bacteria broke down PET microplastics over a 60-day period, pointing toward a potential biological tool for removing plastic contamination from water treatment systems.

2021 1 citations
Article Tier 2

A sequence- and structure-based characterization of microbial enzymes identifies P. stutzeri as a plastic-degrading species

Researchers characterized microbial enzymes with potential plastic-degrading capabilities, focusing on PETase and MHETase enzyme systems. The study identified Pseudomonas stutzeri as a species with notable plastic degradation potential, contributing to the growing understanding of biological approaches for addressing plastic pollution through enzymatic bioremediation.

2024 2 citations
Article Tier 2

Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET

This review discusses the role of enzymatic biocatalysis in PET plastic degradation, examining how the discovery of PETase and subsequent enzyme engineering have advanced biodegradation as an alternative to chemical and mechanical recycling for one of the most produced plastics globally.

2021 International Journal of Molecular Sciences 97 citations
Article Tier 2

Recent advances in enzyme engineering for improved deconstruction of poly(ethylene terephthalate) (PET) plastics

This review covers recent progress in engineering enzymes that can break down PET plastic, the material used in water bottles and food containers. While natural enzymes that digest PET have been discovered, they are not yet fast or durable enough for industrial-scale recycling. Advances in protein engineering, directed evolution, and computational design are steadily improving these enzymes, which could eventually provide a sustainable way to recycle PET and reduce microplastic pollution at its source.

2025 Communications Materials 7 citations
Systematic Review Tier 1

Microbial degradation of polyethylene terephthalate: a systematic review

This systematic review examines how microorganisms like bacteria and fungi can break down PET plastic, one of the most common types of plastic waste. The research identifies several promising biological approaches that could help reduce plastic pollution without the harmful side effects of chemical recycling methods. Finding better ways to break down plastic waste is critical for reducing the microplastics that end up in our water, food, and bodies.

2022 SN Applied Sciences 68 citations
Article Tier 2

Marine PET Hydrolase (PET2): Assessment of Terephthalate- and Indole-Based Polyesters Depolymerization

Researchers characterized a marine enzyme (PET2) capable of breaking down PET plastic and related polyester materials under relatively mild conditions. Discovering and engineering enzymes that can degrade PET could help address the massive accumulation of PET microplastics in ocean environments.

2023 Preprints.org 1 citations
Article Tier 2

Microbial Polyethylene Terephthalate Hydrolases: Current and Future Perspectives

This review surveys microbial enzymes capable of breaking down PET plastic, focusing on the structure and function of key hydrolases like PETase and cutinases. Researchers found that while several enzymes show promising PET-degrading activity, most work slowly and under limited temperature conditions, with engineered variants showing improved performance. The study highlights both the potential and the current limitations of using biological approaches for plastic waste management.

2020 Frontiers in Microbiology 168 citations
Article Tier 2

Application of PETase in Plastic Biodegradation and Its Synthesis

This review examines how PETase enzymes can be used to biodegrade plastic waste, particularly polyethylene terephthalate, which is one of the most widely used plastics globally. Researchers discuss recent advances in modifying PETase enzymes for improved efficiency and establishing sustainable synthesis platforms. The study suggests that enzymatic biodegradation offers a promising biological solution to the growing plastic pollution crisis.

2024 E3S Web of Conferences 2 citations
Review Tier 2

A focused review on recycling and hydrolysis techniques of polyethylene terephthalate

This review examines techniques for recycling polyethylene terephthalate (PET), one of the most common plastics found as microplastic pollution. Chemical recycling through hydrolysis shows the most promise for breaking PET back into its original building blocks for reuse. Improving PET recycling is important because reducing plastic waste at the source is one of the most effective ways to decrease microplastic contamination in the environment.

2023 Polymer Engineering and Science 154 citations
Article Tier 2

Biodegradation of Microplastic Derived from Poly(ethylene terephthalate) with Bacterial Whole-Cell Biocatalysts

Engineered bacterial whole-cell biocatalysts were used to biodegrade PET microplastics under alkaline conditions, with the strain using PET as a sole carbon source and producing monomers that did not accumulate due to continuous cellular metabolism. The study demonstrates a combined enzymatic-microbial approach that overcomes product inhibition in enzymatic PET degradation.

2018 Polymers 158 citations
Article Tier 2

Marine hydrocarbon-degrading bacteria breakdown poly(ethylene terephthalate) (PET)

Scientists used microcosm studies to investigate whether marine hydrocarbon-degrading bacteria can break down PET plastic, finding that specific bacterial strains could colonize and degrade PET surfaces, offering insights into natural plastic biodegradation in the ocean.

2020 The Science of The Total Environment 108 citations
Article Tier 2

Microbes in Plastic Degradation

This review examines how microorganisms can break down common plastics like polyethylene and PET through enzymatic processes. Researchers summarized the key bacterial and fungal species capable of degrading plastics and the conditions that affect degradation rates. The study highlights that while microbial plastic degradation is promising, natural breakdown is slow and more research is needed to make biological solutions practical at scale.

2024 International Journal of Current Science Research and Review 4 citations
Article Tier 2

Microbial Genes for a Circular and Sustainable Bio-PET Economy

This review examined the microbial genes and enzymes capable of degrading polyethylene terephthalate (PET) and related polyesters, discussing how these biological systems could underpin a circular bio-PET economy where degradation products serve as feedstocks for new polymer synthesis.

2019 Genes 138 citations
Article Tier 2

Hydrolase and plastic-degrading microbiota explain degradation of polyethylene terephthalate microplastics during high-temperature composting

Researchers tested a PET-degrading enzyme (WCCG) in high-temperature composting and found that adding the enzyme achieved 35% PET degradation, while native plastic-degrading microbiota alone (including Acinetobacter and Bacillus) reduced PET by 26%, suggesting both enzymatic and microbial approaches can address PET microplastic pollution.

2023 Bioresource Technology 24 citations