Papers

61,005 results
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Article Tier 2

Unignorable environmental risks: Insight into differential responses between biofilm and plastisphere in sulfur autotrophic denitrification system upon exposure to quaternary ammonium compounds

This study found that microplastics in wastewater treatment plants collect more antibiotic resistance genes and disease-causing bacteria on their surfaces than regular biofilms, especially when exposed to common disinfectant chemicals. The plastic surfaces act as hotspots where dangerous bacteria gather and share resistance genes more easily. This raises concerns that microplastics leaving treatment plants could spread antibiotic-resistant infections into the environment.

2025 Journal of Hazardous Materials 7 citations
Article Tier 2

Microplastic biofilm may shape microbial community enriched with antibiotic resistance genes to enhance nitrogen transformation under antibiotic stress

This study found that biofilms growing on PVC microplastics in water helped remove nitrogen pollutants but also concentrated antibiotic resistance genes, with the same bacteria often carrying both pollution-cleaning and drug-resistance capabilities. The findings raise concerns that microplastic pollution in waterways could accelerate the spread of antibiotic-resistant bacteria, which poses a growing threat to human health.

2025 Journal of Hazardous Materials 12 citations
Article Tier 2

Microplastics enhanced the resistant genes spread under disinfectant replacement exposure in partial nitrification-anammox systems

Researchers investigated how alternating disinfectant exposure affects the spread of antibiotic resistance genes on microplastic biofilms in wastewater treatment systems. They found that switching between different disinfectants increased the risk of resistance gene transmission, with PET and polyethylene microplastics serving as vectors for both resistant bacteria and nitrogen-removing microorganisms. The study raises concerns that microplastics in wastewater systems may accelerate the spread of antimicrobial resistance under common disinfection practices.

2025 Chemical Engineering Journal 1 citations
Article Tier 2

Fates of extracellular and intracellular antibiotic resistance genes in activated sludge and plastisphere under sulfadiazine pressure

Researchers found that microplastics in wastewater treatment systems act as reservoirs for antibiotic resistance genes, with the plastic surfaces (plastisphere) harboring more resistance genes than the surrounding sludge. When exposed to the antibiotic sulfadiazine, the spread of resistance genes on microplastic surfaces increased, and DNA from potential pathogens was detected. This suggests that microplastics leaving wastewater treatment plants could carry drug-resistant bacteria into waterways, posing a risk to public health.

2023 Water Research 41 citations
Article Tier 2

Microplastics shape microbial interactions and affect the dissemination of antibiotic resistance genes in different full-scale wastewater treatment plants

A study of three full-scale wastewater treatment plants found that microplastics were associated with increased spread of antibiotic resistance genes (ARGs), with microplastic surfaces appearing to facilitate microbial interactions that promote ARG transfer. This is a significant public health concern because wastewater plants that fail to fully remove microplastics may also be inadvertently accelerating the dissemination of antibiotic resistance into receiving waterways.

2023 The Science of The Total Environment 14 citations
Article Tier 2

Contribution of microplastic particles to the spread of resistances and pathogenic bacteria in treated wastewaters

Researchers studied microplastic particles collected from treated wastewater effluents and found that MPs harbored significantly higher loads of antibiotic resistance genes and pathogenic bacteria compared to surrounding water, suggesting MPs facilitate their environmental spread.

2021 Water Research 140 citations
Article Tier 2

Responses of bacterial communities and resistance genes on microplastics to antibiotics and heavy metals in sewage environment

Polyvinyl chloride microplastics in sewage enriched pathogenic bacteria and antibiotic resistance genes on their surfaces, and the presence of heavy metals and antibiotics altered but did not eliminate this enrichment over time. The findings suggest microplastics in wastewater environments could facilitate the spread of antibiotic resistance through the microbial community.

2020 Journal of Hazardous Materials 179 citations
Article Tier 2

Growth and prevalence of antibiotic-resistant bacteria in microplastic biofilm from wastewater treatment plant effluents

Researchers studied antibiotic-resistant bacteria growing in biofilms on microplastic surfaces in wastewater treatment plant effluent. The study found that microplastic biofilms accumulated antibiotic-resistant bacteria including Pseudomonas, Aeromonas, and Bacillus, and that these biofilms harbored higher concentrations of resistance genes compared to surrounding water, suggesting microplastics may serve as reservoirs for antibiotic resistance.

2022 The Science of The Total Environment 51 citations
Article Tier 2

Microplastics exhibit accumulation and horizontal transfer of antibiotic resistance genes

Researchers investigated whether microplastics in wastewater treatment plants can accumulate and spread antibiotic resistance genes. They found that bacteria growing on microplastic surfaces in treatment tanks harbored antibiotic resistance genes and transferred them at higher rates than bacteria in the surrounding water. This suggests microplastics in wastewater systems may serve as hotspots for spreading antibiotic resistance, posing potential risks to both ecosystems and human health.

2023 Journal of Environmental Management 49 citations
Article Tier 2

Antibiotic resistance genes and virulence factors in the plastisphere in wastewater treatment plant effluent: Health risk quantification and driving mechanism interpretation

Researchers found that microplastics in treated wastewater carry significantly more disease-causing bacteria, antibiotic resistance genes, and virulence factors on their surfaces compared to the surrounding water. This means microplastics released from wastewater treatment plants into rivers and lakes could spread antibiotic-resistant infections, posing a direct risk to communities that rely on these water sources.

2024 Water Research 54 citations
Article Tier 2

Different microplastics distinctively enriched the antibiotic resistance genes in anaerobic sludge digestion through shifting specific hosts and promoting horizontal gene flow

Researchers examined how polyethylene and polyvinyl chloride microplastics affect antibiotic resistance genes during sewage sludge digestion and found that both plastic types promoted the spread of resistance genes, but through different mechanisms. Polyethylene surfaces attracted specific bacteria that carry resistance genes, while PVC promoted horizontal gene transfer between organisms. The study raises concerns about wastewater treatment plants becoming hotspots for antibiotic resistance when microplastics are present.

2022 Water Research 113 citations
Article Tier 2

Microplastics accelerate nitrification, shape the microbial community, and alter antibiotic resistance during the nitrifying process

Researchers found that adding microplastics to wastewater treatment systems actually sped up nitrification (a key step in processing sewage) but also promoted the growth of antibiotic-resistant bacteria. Even biodegradable PLA plastics, often considered more environmentally friendly, significantly increased antibiotic resistance genes. This study warns that microplastics in wastewater systems could be accelerating the spread of antibiotic resistance, a major public health threat.

2024 The Science of The Total Environment 12 citations
Article Tier 2

Decoding the microplastic Micro-interface: a complex Web of gene transfer and pathogenic threats in wastewater

Researchers used metagenomics to study how microplastic surfaces in wastewater treatment systems serve as hotspots for antibiotic resistance genes and pathogenic bacteria. They found that microplastic micro-interfaces supported more robust microbial networks and facilitated horizontal gene transfer of resistance and virulence genes more actively than surrounding environments. The study suggests that microplastics in wastewater may accelerate the spread of antibiotic resistance and increase pathogenicity risks.

2025 Environment International 1 citations
Article Tier 2

Antibiotic-driven shifts in bacterial dynamics of the polyethylene terephthalate and low density polyethylene plastisphere in wastewater treatment systems

Researchers studied how antibiotic exposure shifts the bacterial communities colonizing PET and LDPE microplastic surfaces in activated sludge from wastewater treatment plants, finding that antibiotics altered plastisphere microbial composition and increased antibiotic resistance gene prevalence.

2025 Journal of Hazardous Materials
Article Tier 2

Microplastics as hubs enriching antibiotic-resistant bacteria and pathogens in municipal activated sludge

Researchers demonstrated that microplastics in municipal wastewater treatment plants act as "hubs," selectively concentrating antibiotic-resistant bacteria and pathogens in their surface biofilms, with antibiotic-resistance genes enriched up to 4.5-fold compared to sand particles — raising concerns about microplastics spreading drug-resistant microbes into the environment.

2021 Journal of Hazardous Materials Letters 181 citations
Article Tier 2

Impacts of disinfectant and antipyretic on aged ethylene-vinyl acetate copolymer microplastics in hospital wastewater: Resistance genes, microbial community and carbon source metabolism

Researchers examined how two common hospital chemicals — a disinfectant (benzethonium chloride) and a painkiller (acetaminophen) — affect the microplastic particles made of ethylene-vinyl acetate that end up in hospital wastewater. Aged EVA microplastics exposed to these chemicals became better carriers for antibiotic resistance genes and promoted more microbial colonization than fresh plastics, raising concerns about hospitals as sources of resistance gene spread through microplastics. This highlights a under-studied pathway by which microplastics in healthcare settings could contribute to the global antibiotic resistance crisis.

2025 Journal of Hazardous Materials 1 citations
Article Tier 2

Enhanced propagation of intracellular and extracellular antibiotic resistance genes in municipal wastewater by microplastics

Researchers investigated how microplastics in municipal wastewater can carry and promote the spread of antibiotic resistance genes, including those found both inside and outside bacterial cells. They found that microplastics adsorbed both types of resistance genes and enhanced their transfer between bacteria through horizontal gene transfer. The study reveals that microplastics in wastewater systems may act as an underappreciated accelerator of antibiotic resistance spread.

2021 Environmental Pollution 102 citations
Article Tier 2

Microplastic biofilms in water treatment systems: Fate and risks of pathogenic bacteria, antibiotic-resistant bacteria, and antibiotic resistance genes

This review examines how microplastics in drinking water and wastewater treatment plants develop biofilms that harbor dangerous bacteria and antibiotic resistance genes. The biofilm-coated microplastics can protect pathogens from disinfection processes, allowing them to survive treatment and potentially reach tap water. This raises concerns about microplastics serving as vehicles for antibiotic-resistant bacteria in our water supply.

2023 The Science of The Total Environment 50 citations
Article Tier 2

From Interface to Cell: The Complex Interaction and Transfer Process Coupling Mechanism between Microplastics and Antibiotic Resistance Genes

Researchers examined how microplastic surfaces act as vectors for spreading antibiotic resistance genes in wastewater treatment systems. The study found that aged microplastics of PET, PE, and PP promoted bacterial adhesion, enhanced horizontal gene transfer, and triggered overproduction of reactive oxygen species, ultimately amplifying the spread of antimicrobial resistance through multiple molecular mechanisms.

2026 Environmental Science & Technology
Article Tier 2

The stress response of tetracycline resistance genes and bacterial communities under the existence of microplastics in typical leachate biological treatment system

Researchers studied how polystyrene and polyethylene microplastics affect tetracycline resistance genes and bacterial communities in a leachate biological treatment system. They found that microplastics served as hotspots for antibiotic resistance genes, with biofilms on the plastic surfaces harboring significantly higher gene abundances than the surrounding liquid. The study suggests that microplastics in waste treatment systems may accelerate the spread of antibiotic resistance.

2024 Journal of Environmental Management 11 citations
Article Tier 2

Plastisphere enhanced resistance genes propagation in sulfur autotrophic/heterotrophic denitrification system under mixed quaternary  ammonium compounds pressure

A laboratory wastewater treatment study found that microplastic surfaces — particularly those of biodegradable polylactic acid plastics — create enriched "plastisphere" communities that accumulate and spread antibiotic resistance genes more aggressively than the surrounding biofilm, especially under the additional stress of quaternary ammonium compound disinfectants. The biodegradable plastic appeared to provide extra carbon and energy to microbes, inadvertently turbocharging resistance gene proliferation. This challenges the assumption that switching to biodegradable plastics in wastewater systems is straightforwardly beneficial.

2026 Bioresource Technology
Article Tier 2

Fragmented Microplastics Synergize with Biological Treatment To Potentiate Antibiotic Resistance Dissemination during Sewage Treatment

Researchers used metagenomic sequencing and high-throughput qPCR across a full sewage treatment chain to show that fragmented microplastics preferentially concentrate clinically relevant antibiotic resistance genes, with MP-bound genes contributing up to 43% of intracellular resistance genes detected in treated effluent, and Acinetobacter emerging as a key resistance indicator.

2026 Environmental Science & Technology
Article Tier 2

Interactions of microplastics, antibiotics and antibiotic resistant genes within WWTPs

This review examined the interactions between microplastics, antibiotics, and antibiotic resistance genes within wastewater treatment plants, analyzing how MPs serve as carriers for antimicrobial compounds and facilitate the spread of resistance in microbial communities.

2021 The Science of The Total Environment 145 citations
Article Tier 2

Effects of polyvinylchloride microplastics on the toxicity of nanoparticles and antibiotics to aerobic granular sludge: Nitrogen removal, microbial community and resistance genes

Researchers examined how PVC microplastics affect wastewater treatment systems that also contain copper oxide nanoparticles and the antibiotic ciprofloxacin. They found that low concentrations of microplastics actually reduced some toxic effects of the other pollutants, but higher concentrations worsened nitrogen removal efficiency and increased antibiotic resistance genes. The study highlights the complex ways microplastics can alter the behavior of other contaminants in water treatment.

2023 Environmental Research 20 citations