Papers

61,005 results
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Article Tier 2

Microplastics: an often-overlooked issue in the transition from chronic inflammation to cancer

This review explores how microplastics that accumulate in the human body may trigger long-lasting inflammation, which is a known driver of cancer development. The authors describe how microplastics can disrupt the gut microbiome, activate immune responses, and alter signaling pathways in ways that could promote tumor growth over time.

2024 Journal of Translational Medicine 46 citations
Article Tier 2

Microscopic menace: exploring the link between microplastics and cancer pathogenesis

This review examines the growing evidence linking microplastic exposure to cancer development in humans. Microplastics can accumulate in the body and trigger inflammation, oxidative stress, and other biological changes associated with tumor growth. While more clinical research is needed, the review highlights that microplastics should be taken seriously as a potential factor in cancer risk.

2025 Environmental Science Processes & Impacts 8 citations
Systematic Review Tier 1

From Exposure to Oncogenesis: the Role of Microplastics and Associated Pollutants in Cancer - a Literature Review

This literature review examined the growing evidence linking microplastic exposure to cancer development. Microplastics have been found in human lung, liver, and colon tissue, and research suggests they may promote cancer through chronic inflammation, oxidative stress, and by carrying known carcinogens like heavy metals and persistent organic pollutants into the body.

2025 International Journal of Innovative Technologies in Social Science
Article Tier 2

Microplastics as emerging carcinogens: from environmental pollutants to oncogenic drivers

This review examines growing evidence that microplastics and nanoplastics may play a role in cancer development, with these particles found in human tumor tissues from the lungs, colon, stomach, breast, and other organs. The particles appear to promote cancer through chronic inflammation, oxidative stress, DNA damage, and disruption of key cancer-related signaling pathways. While direct proof of causation in humans is still lacking, the accumulating evidence from lab studies, animal experiments, and human tissue analysis suggests microplastics deserve serious attention as potential contributors to cancer risk.

2025 Molecular Cancer 7 citations
Article Tier 2

The micro(nano)plastics perspective: exploring cancer development and therapy

This review explores the emerging link between microplastics and cancer development. Microplastics can trigger chronic inflammation, oxidative stress, and hormone disruption, all of which are known pathways that may promote cancer growth. Interestingly, researchers are also studying whether engineered microplastics could be used as drug carriers for cancer therapy, though long-term effects remain unclear.

2025 Molecular Cancer 52 citations
Article Tier 2

Plastic pollution-Microplastics: Cancer related issues

This review examines how microplastics may contribute to cancer risk, summarizing evidence that ingested microplastics can cross the gut epithelium, accumulate in tissues, induce oxidative stress and inflammation, and carry carcinogenic chemical additives.

2025 World Journal of Biology Pharmacy and Health Sciences
Article Tier 2

Evaluating the relationship between microplastics and nanoplastics contamination and diverse cancer types development

This review examines growing evidence that micro- and nanoplastics found in human tissues may contribute to cancer development through several pathways. These tiny particles can generate harmful molecules called reactive oxygen species, cause chronic inflammation, and disrupt cell growth signals, all of which are known to promote cancer. While long-term, high-level exposure likely poses the greatest risk, more research is needed to understand the full cancer-related dangers of microplastic exposure.

2025 Environmental Pollution 6 citations
Article Tier 2

Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans?

This review examines how microplastics and nanoplastics enter the human body through food, water, and air, and how they may contribute to cancer development. Common plastic types like polystyrene and PVC, along with toxic chemicals they carry such as PAHs and PCBs, have been linked to DNA damage, oxidative stress, and inflammation, all of which can promote cancer. The paper highlights that while the evidence is growing, more research is needed to understand the full cancer risk from chronic microplastic exposure.

2022 Chemosphere 367 citations
Article Tier 2

From exposure to oncogenesis: a review on the multifaceted roles of microplastics in tumor initiation and progression

This review examined the evidence linking microplastic exposure to tumor initiation and progression, covering physical, chemical, and inflammatory mechanisms by which MPs may promote oncogenesis. The authors conclude that while current evidence is largely preclinical, accumulating data warrant serious concern about microplastics as environmental carcinogens.

2025 Journal of Translational Medicine
Article Tier 2

Microplastics and cancer

This review examines evidence linking microplastics to cancer risk, noting that microplastics have been detected at higher concentrations in human tumor tissues than adjacent healthy tissue, and that they can act as vectors for carcinogens while inducing oxidative stress, inflammation, and genotoxicity.

2025 European Journal of Cancer Prevention
Article Tier 2

The impact of environmental microplastics as emerging carcinogens: A public health concern

This review investigated the mechanisms by which microplastics may contribute to cancer development, examining studies from 2010 to 2024. Researchers found that microplastics can induce oxidative stress, inflammation, and DNA damage through multiple pathways, and that human exposure occurs primarily through ingestion, inhalation, and dermal contact. The study suggests that microplastics represent an emerging class of environmental concern warranting further investigation into their long-term health effects.

2024 Multidisciplinary Reviews 2 citations
Article Tier 2

Exposure and inhaling of microplastics: An evidence of cause of cancer

This review examines epidemiological and experimental evidence linking microplastic inhalation and ingestion to cancer risk, covering mechanisms including oxidative stress, inflammation, and genotoxicity from both particles and associated chemical additives. It highlights lung and gastrointestinal cancers as priority areas of concern.

2025 World Journal of Biology Pharmacy and Health Sciences
Article Tier 2

Orally Ingested Micro- and Nano-Plastics: A Hidden Driver of Inflammatory Bowel Disease and Colorectal Cancer.

This review synthesizes evidence linking ingested micro- and nano-plastics to inflammatory bowel disease and colorectal cancer risk, proposing that microplastics act as a hidden driver of gut inflammation in vulnerable populations. The authors argue that intestinal accumulation of microplastics triggers immune and oxidative stress pathways that contribute to disease progression.

2024 Cancers
Article Tier 2

The hidden threat: Microplastics and cancer biology

This review synthesizes current research on the potential links between micro- and nanoplastic exposure and cancer biology, examining how these particles may contribute to tumor development in organs including the gut, lungs, skin, liver, kidney, and brain. The study suggests that chronic exposure to plastic particles can trigger molecular changes such as oxidative stress, inflammation, and DNA damage that are associated with cancer initiation, though clear causal evidence in humans is still lacking.

2026 Journal of Hazardous Materials
Article Tier 2

The alarming link between environmental microplastics and health hazards with special emphasis on cancer

This review describes how microplastics enter the human body through the nose, skin, and mouth, then penetrate cells where they can alter gene expression, fuel inflammation, disrupt hormone signaling, and promote uncontrolled cell growth. Studies have linked microplastic exposure to cancers of the lungs, blood, breast, prostate, and ovaries, though the precise molecular mechanisms still need further investigation.

2024 Life Sciences 90 citations
Article Tier 2

Microplastics – A Growing Concern as Carcinogens in Cancer Etiology: Emphasis on Biochemical and Molecular Mechanisms

This review describes how microplastics smaller than 5 mm can enter human cells and promote cancer development through multiple pathways, including DNA damage, oxidative stress, chronic inflammation, and disruption of cell growth controls. Microplastics also carry other contaminants into the body, and their accumulation in tissues raises concerns about long-term cancer risk, particularly in the lungs, skin, and digestive system.

2024 Cell Biochemistry and Biophysics 43 citations
Article Tier 2

Exposure and inhaling of microplastics: An evidence of cause of cancer

This review examined the evidence linking microplastic inhalation to cancer risk, covering how inhaled MPs accumulate in the lungs, trigger chronic inflammation, oxidative stress, and DNA damage, and may contribute to lung carcinogenesis. The authors identified microplastic inhalation as an underappreciated occupational and environmental cancer risk.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Microplastics and Nanoplastics in Cancer Progression: Biology and Public Health

This review examines emerging evidence that microplastics and nanoplastics may contribute to cancer-related processes by crossing biological barriers and accumulating in tissues. The study highlights that these particles can cause oxidative stress, inflammation, DNA damage, and barrier dysfunction at the cellular level, and may promote tumor-supporting processes including angiogenesis and immune evasion.

2025 Biomedicines 1 citations
Article Tier 2

Do microplastics (MPs) and nanoplastics (NPs) directly contribute to human carcinogenesis?

This review examines whether microplastics and nanoplastics could directly contribute to cancer development in humans. Evidence from lab and animal studies shows these particles can cause DNA damage, chronic inflammation, oxidative stress, and disrupt important cancer-related signaling pathways. While a direct causal link to human cancer has not been proven yet, the review argues that microplastics should be considered potential cancer-promoting agents that warrant urgent further research.

2025 Environmental Pollution 7 citations
Article Tier 2

Microplastics: An emerging environmental risk factor for gut microbiota dysbiosis and cancer development?

This review examines how microplastics may disrupt the gut microbiome and immune system in ways that could promote cancer development. Evidence from recent studies suggests microplastics can cause chronic inflammation, alter the balance of gut bacteria, and trigger molecular pathways linked to several cancer types including lung, liver, breast, and colon cancer. While more human research is needed, the review highlights a concerning connection between microplastic exposure, gut health, and cancer risk.

2025 Environmental Chemistry and Ecotoxicology 8 citations
Article Tier 2

The Relationship Between Microplastics and Nanoplastics with Cancer: An Emerging Health Concern

This review explores the emerging relationship between micro- and nanoplastic exposure and cancer risk in humans. Researchers summarized evidence suggesting that microplastics can carry carcinogenic substances and may trigger inflammatory and oxidative stress pathways linked to tumor development. The study highlights that while early evidence raises concern, more research is needed to establish clear causal connections between plastic particle exposure and specific cancer types.

2024 International Journal of Hematology and Oncology 3 citations
Systematic Review Tier 1

Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review

This systematic review examines the potential link between microplastics and nanoplastics and colorectal cancer. The research highlights how these tiny particles may contribute to cancer development through mechanisms like chronic inflammation and cellular damage in the gut. While more studies are needed, the findings raise important questions about the long-term consequences of ingesting plastic particles.

2025 Frontiers in Public Health 4 citations
Article Tier 2

Small Plastics, Big Inflammatory Problems.

This review examined how micro- and nano-plastics trigger inflammatory responses through interactions with immune cells, finding that particles activate multiple signaling pathways including NF-kB and NLRP3 inflammasome, potentially contributing to chronic low-grade inflammation linked to cardiovascular disease, autoimmune disorders, and cancer.

2023 Advances in experimental medicine and biology
Article Tier 2

Impact of Microplastics on Human health: Time for us to get attentive- before it’s too late

This paper reviewed the growing evidence on microplastic impacts on human health, covering ingestion, inhalation, and dermal exposure routes, and the potential for microplastics to cause inflammation, oxidative stress, and endocrine disruption. The authors argue the problem demands urgent regulatory attention.

2024 Diabetes Asia Journal.