Papers

61,005 results
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Article Tier 2

The gut microbiota: A key player in cadmium toxicity - implications for disease, interventions, and combined toxicant exposures

This review examines how cadmium, a toxic heavy metal found in contaminated soil and water, damages health partly by disrupting gut bacteria. The connection to microplastics is significant because microplastics are known to absorb and carry heavy metals like cadmium, potentially increasing our exposure to these toxins and compounding the damage to our gut health.

2024 Journal of Trace Elements in Medicine and Biology 25 citations
Article Tier 2

Interactions between environmental pollutants and gut microbiota: A review connecting the conventional heavy metals and the emerging microplastics

This review examines how environmental pollutants, including both heavy metals and microplastics, interact with gut bacteria in humans and animals. The authors found that these pollutants can disrupt the balance of gut microbiota, which may contribute to various health problems, and that gut bacteria can also transform pollutants in ways that change their toxicity.

2025 Environmental Research 13 citations
Article Tier 2

A critical review on the interactions of microplastics with heavy metals: Mechanism and their combined effect on organisms and humans

This review examines how microplastics interact with heavy metals in the environment and what their combined effects mean for organisms and human health. Microplastics absorb heavy metals from surrounding water and soil, and when ingested, the acidic conditions in the gut can cause those metals to be released inside the body. The combination of microplastics and heavy metals may be more toxic than either pollutant alone, creating a compounded health risk.

2021 The Science of The Total Environment 545 citations
Article Tier 2

Microplastics and their interactions with microbiota

This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.

2023 Heliyon 64 citations
Article Tier 2

Interactions Between Microplastics and Heavy Metals in Aquatic Environments: A Review

This review examines how microplastics interact with heavy metals in water, with a particular focus on the role that microorganisms play in driving these interactions. Bacteria that colonize microplastic surfaces can change how metals bind to and release from the particles, potentially increasing their toxicity. The combined threat of microplastics and heavy metals to aquatic ecosystems and human health through seafood consumption is a growing concern that needs more research.

2021 Frontiers in Microbiology 271 citations
Review Tier 2

Interactions between microplastics (MPs) and trace/toxic metals in marine environments: implications and insights—a comprehensive review

This review examines how microplastics interact with trace and toxic metals in ocean environments, finding that plastic particles can adsorb metals onto their surfaces and alter how those metals move through marine ecosystems. These interactions can increase metal toxicity, reduce the availability of essential nutrients for marine life, and disrupt ocean food chains in ways that may ultimately affect seafood safety for humans.

2024 Environmental Science and Pollution Research 20 citations
Article Tier 2

How do microplastics affect the composition and function of gut microbiota?

Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full scope of these effects in humans remains understudied.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

How do microplastics affect the composition and function of gut microbiota?

Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full extent of these effects in humans remains poorly characterized and understudied.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Influence of toxic metal exposure on the gut microbiota (Review)

This review summarized evidence on how heavy metals and toxic metals alter gut microbiota composition, diversity, and function, finding metal-specific effects depending on compound form, exposure route, and duration that complicate direct comparisons across studies.

2021 World Academy of Sciences Journal 40 citations
Article Tier 2

Influence of Microplastics on the Mobility, Bioavailability, and Toxicity of Heavy Metals: A Review

This review examines how microplastics interact with heavy metals in the environment, potentially influencing the metals' mobility, bioavailability, and toxicity to living organisms. Researchers found that microplastics can adsorb heavy metals and transport them to new locations, but the interactions depend on the type of plastic, metal, and environmental conditions. The study highlights that microplastics acting as carriers for toxic metals represents an underappreciated environmental and health risk.

2021 Bulletin of Environmental Contamination and Toxicology 115 citations
Article Tier 2

Role-Playing Between Environmental Pollutants and Human Gut Microbiota: A Complex Bidirectional Interaction

This review examined the bidirectional relationship between environmental pollutants, including microplastics, and the human gut microbiota, highlighting how toxicants alter microbial communities while gut bacteria can metabolize or modify pollutant toxicity.

2022 Frontiers in Medicine 38 citations
Article Tier 2

Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health

This review explores how microplastics interact with microorganisms in the environment and within the gut, examining implications for both animal and human health. Researchers found that microplastics can alter gut microbiota composition, promote the spread of antibiotic-resistant bacteria, and amplify the toxicity of other environmental pollutants. The study suggests that the interaction between microplastics and gut microorganisms is an important emerging area for understanding health risks.

2019 The Science of The Total Environment 405 citations
Article Tier 2

The role of gut microbiota in MP/NP-induced toxicity

This review summarizes how micro- and nanoplastics disrupt gut bacteria and why that matters for overall health. The tiny plastic particles change the composition and function of the gut microbiome, which can trigger inflammation, weaken the intestinal barrier, and potentially contribute to diseases beyond the gut through the immune and nervous systems.

2024 Environmental Pollution 22 citations
Article Tier 2

Reviewing the role of microplastics as carriers for microorganisms in absorbing toxic trace elements

This review examines how microplastics serve as carriers for both harmful bacteria and toxic metals in the environment. Bacteria colonize microplastic surfaces and form biofilms, which can concentrate dangerous trace elements and help spread pathogens to new areas. This dual role as a transport vehicle for both chemical and biological contaminants increases the potential risk to human health through contaminated water and food.

2024 Environmental Science and Pollution Research 14 citations
Review Tier 2

Microplastics and potentially toxic elements: A review of interactions, fate and bioavailability in the environment

This review summarizes how microplastics interact with toxic metals in the environment, finding that microplastics absorb and transport metals through soil and water via processes like electrostatic attraction and surface bonding. When organisms consume microplastics carrying toxic metals, they can experience greater harm than from either pollutant alone. This combined threat is relevant to human health because contaminated microplastics in the food chain could deliver concentrated doses of toxic metals to people through food and water.

2023 Environmental Pollution 33 citations
Article Tier 2

Interaction of microplastics with heavy metals in soil: Mechanisms, influencing factors and biological effects

This review summarizes how microplastics and heavy metals interact in soil, where microplastics can absorb and carry toxic metals through the food chain and into the human body. Aging and weathering of microplastics changes their surface properties, making them better at picking up heavy metals, which raises concerns about combined exposure through contaminated crops and water.

2024 The Science of The Total Environment 96 citations
Article Tier 2

Microplastics as a Trojan horse for trace metals

Researchers demonstrated that microplastics can absorb toxic metals from surrounding water and release them in conditions mimicking the human gut, essentially acting as a "Trojan horse" that transports heavy metals like lead, arsenic, and chromium into the body alongside the plastic particles.

2021 Journal of Hazardous Materials Letters 102 citations
Article Tier 2

Microplastic co-exposure elevates cadmium accumulation in mouse tissue after rice consumption: Mechanisms and health implications

In a mouse study, eating cadmium-contaminated rice alongside common microplastics led to 17-38% more cadmium accumulating in body tissues than eating the rice alone. The microplastics changed gut bacteria composition, which increased cadmium solubility and transport across the intestinal wall. This is directly relevant to human health because both microplastics and cadmium are common contaminants in rice, and their combined exposure may increase toxic metal absorption.

2024 Journal of Hazardous Materials 11 citations
Article Tier 2

Microplastics and the gut microbiome: Emerging health concerns and strategies

This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.

2025 Journal of Environmental Biology
Article Tier 2

Co-exposure with cadmium elevates the toxicity of microplastics: Trojan horse effect from the perspective of intestinal barrier

When mice were exposed to both microplastics and the toxic metal cadmium together, the health damage to their intestines and liver was significantly worse than exposure to either pollutant alone. The microplastics acted like a "Trojan horse," carrying cadmium past the gut barrier and increasing its accumulation in the body, while also disrupting the gut microbiome.

2024 Journal of Hazardous Materials 72 citations
Article Tier 2

Co-occurrence and Interaction of Microplastics with Heavy Metals

This review examines the co-occurrence of microplastics and heavy metals in aquatic and terrestrial ecosystems, synthesizing evidence on how MPs adsorb metals, alter their bioavailability, and facilitate their transfer up food chains, compounding toxicological risks beyond either pollutant alone.

2025
Article Tier 2

Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks

This review summarizes evidence that microplastics disrupt the gut microbiome, the community of bacteria in our digestive system that plays a key role in immunity, metabolism, and overall health. By altering gut bacteria balance and triggering inflammation, microplastic exposure may contribute to chronic conditions including inflammatory bowel disease, metabolic disorders, and potentially even neurological problems through the gut-brain connection.

2024 Frontiers in Cellular and Infection Microbiology 82 citations
Article Tier 2

Association between microplastics exposure and gut microbiota and metabolites in older adults: A cross-sectional study

Researchers analyzed fecal samples from 45 older adults to assess the relationship between microplastic exposure and gut microbiota. They found an average of 70 microplastic particles per gram of feces, primarily PVC, butadiene rubber, and polyethylene, and observed that microplastic exposure was associated with changes in gut microbial diversity and metabolite levels. The study suggests that microplastics may influence gut health in older adults by altering bacterial community composition and metabolic pathways.

2025 Environmental Research 1 citations
Article Tier 2

Interactions and effects of microplastics with heavy metals in aquatic and terrestrial environments

This review explores how microplastics absorb toxic heavy metals from the environment and what happens when organisms ingest these contaminated particles. In the acidic conditions of an animal's digestive system, metals can separate from the plastic and accumulate in body tissues. Since heavy metals can concentrate on microplastics and then transfer up the food chain, this combination poses a compounded health risk to wildlife and potentially to humans who eat contaminated seafood.

2021 Environmental Pollution 546 citations