Papers

61,005 results
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Article Tier 2

[Research progress on the effect of estuary microplastics on antibiotic resistance genes].

This review summarizes research on how microplastics in estuarine environments influence the spread of antibiotic resistance genes (ARGs), focusing on the role of biofilms that form on plastic surfaces. Microplastic biofilms selectively enrich ARG-carrying bacteria and facilitate horizontal gene transfer, increasing the risk of antibiotic resistance dissemination in ecologically and humanly important estuarine zones.

2024 PubMed
Article Tier 2

Prevalence of microplastics, antibiotic resistant genes and microplastic associated biofilms in estuary - A review

This review examined evidence for microplastics, antibiotic resistance genes, and microplastic-associated biofilms in estuarine ecosystems. Microplastics in estuaries serve as substrates for diverse microbial biofilms including pathogens and antibiotic-resistant bacteria, and estuaries are identified as important reservoirs for microplastic-facilitated horizontal gene transfer.

2022 Environmental Engineering Research 12 citations
Article Tier 2

Antagonistic effects of microplastic biofilms on antibiotic resistance gene horizontal transfer in water environments

Microplastics in water environments accumulate bacteria on their surfaces, forming biofilms that were long assumed to accelerate the spread of antibiotic resistance genes between microbes. This study challenges that assumption by showing that microplastic biofilms can actually reduce the rate of antibiotic resistance gene transfer compared to free-floating bacteria — dampening both the promoting effect of certain chemicals and the inhibiting effect of others. The finding adds important nuance to the debate about microplastics as vectors for antibiotic resistance, suggesting the relationship is more complex than a simple amplifier.

2026 Aquatic Toxicology
Article Tier 2

Microplastic pollution increases gene exchange in aquatic ecosystems

Researchers found that microplastics in aquatic environments serve as surfaces where bacteria form biofilms and exchange genes at higher rates than free-living bacteria. The study demonstrated increased transfer of antibiotic resistance genes among a wide range of bacterial species growing on microplastic particles. The findings suggest that microplastic pollution could accelerate the spread of antibiotic resistance in waterways, posing a potential hazard to both ecosystems and human health.

2018 Environmental Pollution 582 citations
Article Tier 2

Conjugative antibiotic-resistant plasmids promote bacterial colonization of microplastics in water environments

Antibiotic-resistant bacteria carrying conjugative plasmids were shown to more effectively colonize microplastic surfaces in water environments, with plasmid transfer rates on plastic surfaces exceeding those in the surrounding water. The study identifies microplastics as hotspots for the spread of antibiotic resistance genes through horizontal gene transfer in aquatic systems.

2022 Journal of Hazardous Materials 49 citations
Article Tier 2

Enhanced propagation of intracellular and extracellular antibiotic resistance genes in municipal wastewater by microplastics

Researchers investigated how microplastics in municipal wastewater can carry and promote the spread of antibiotic resistance genes, including those found both inside and outside bacterial cells. They found that microplastics adsorbed both types of resistance genes and enhanced their transfer between bacteria through horizontal gene transfer. The study reveals that microplastics in wastewater systems may act as an underappreciated accelerator of antibiotic resistance spread.

2021 Environmental Pollution 102 citations
Article Tier 2

Microplastics exhibit accumulation and horizontal transfer of antibiotic resistance genes

Researchers investigated whether microplastics in wastewater treatment plants can accumulate and spread antibiotic resistance genes. They found that bacteria growing on microplastic surfaces in treatment tanks harbored antibiotic resistance genes and transferred them at higher rates than bacteria in the surrounding water. This suggests microplastics in wastewater systems may serve as hotspots for spreading antibiotic resistance, posing potential risks to both ecosystems and human health.

2023 Journal of Environmental Management 49 citations
Article Tier 2

Microplastic-Mediated Dissemination of Antibiotic Resistance Genes in Marine Environments: Mechanisms, Environmental Modulators, and Emerging Risks

This review examines how microplastics serve as vectors for spreading antibiotic resistance genes in marine environments through biofilm formation and horizontal gene transfer. Researchers found that plastic surfaces promote colonization by resistant bacteria, and environmental factors like salinity, UV exposure, and co-occurring heavy metals further accelerate the spread of resistance genes, posing significant ecological and public health risks.

2026 Microplastics
Article Tier 2

Regulation of ARGs abundance by biofilm colonization on microplastics under selective pressure of antibiotics in river water environment

Researchers investigated how biofilms forming on microplastics in river water affect the spread of antibiotic resistance genes under antibiotic pressure. They found that the presence of antibiotics accelerated biofilm colonization on microplastic surfaces and significantly increased the abundance of resistance genes compared to conditions without antibiotics. The study suggests that microplastics in waterways may serve as hotspots for the development and transfer of antibiotic resistance.

2024 Journal of Environmental Management 30 citations
Article Tier 2

From Interface to Cell: The Complex Interaction and Transfer Process Coupling Mechanism between Microplastics and Antibiotic Resistance Genes

Researchers examined how microplastic surfaces act as vectors for spreading antibiotic resistance genes in wastewater treatment systems. The study found that aged microplastics of PET, PE, and PP promoted bacterial adhesion, enhanced horizontal gene transfer, and triggered overproduction of reactive oxygen species, ultimately amplifying the spread of antimicrobial resistance through multiple molecular mechanisms.

2026 Environmental Science & Technology
Article Tier 2

Horizontal Gene Transfer of Antibiotic Resistance Genes in Biofilms

This review explains how bacteria living in biofilms -- sticky communities attached to surfaces -- can rapidly share antibiotic resistance genes with each other through horizontal gene transfer, spreading resistance faster than free-floating bacteria. This is relevant to microplastic pollution because microplastics provide ideal surfaces for biofilm formation, potentially acting as hotspots for the spread of antibiotic resistance in the environment.

2023 Antibiotics 443 citations
Article Tier 2

Selective enrichment of bacterial pathogens by microplastic biofilm

Researchers incubated biofilms on microplastics and natural substrates in freshwater and found that microplastic surfaces selectively enriched bacterial pathogens and antibiotic resistance genes compared to rock and leaf surfaces. The study suggests that microplastics in waterways may serve as hotspots for harmful bacteria and contribute to the spread of antibiotic resistance in the environment.

2019 Water Research 678 citations
Article Tier 2

Microplastics enhance the prevalence of antibiotic resistance genes in mariculture sediments by enriching host bacteria and promoting horizontal gene transfer

Researchers found that polystyrene and PVC microplastics in marine sediments increased the abundance of antibiotic resistance genes by 1.4 to 2.8 times compared to sediment without plastics. PVC was particularly harmful because its chemical additives, including heavy metals and bisphenol A, promoted bacteria to share resistance genes more readily. These findings show that microplastic pollution in oceans is directly contributing to the spread of antibiotic-resistant bacteria, a major public health concern.

2025 Eco-Environment & Health 36 citations
Article Tier 2

Microplastics can selectively enrich intracellular and extracellular antibiotic resistant genes and shape different microbial communities in aquatic systems

Researchers examined how microplastics of different types selectively capture antibiotic resistance genes and shape microbial communities in aquatic systems. They found that microplastics enriched both intracellular and extracellular antibiotic resistance genes, with the enrichment patterns varying by plastic type. The study suggests that microplastics may serve as hotspots for the spread of antimicrobial resistance in wastewater and natural water environments.

2022 The Science of The Total Environment 47 citations
Article Tier 2

Microplastic-Mediated Transfer of Tetracycline Resistance: Unveiling the Role of Mussels in Marine Ecosystems

Researchers found that microplastics can serve as platforms for antibiotic-resistant bacteria to form biofilms in marine environments, facilitating the transfer of resistance genes. In experiments with mussels, polyethylene microplastics significantly increased the rate at which tetracycline resistance genes spread between bacteria. The findings raise concerns that microplastic pollution in the ocean could accelerate the spread of antibiotic resistance, with implications for both ecosystem and public health.

2024 Antibiotics 7 citations
Article Tier 2

[Influencing Factors and Mechanisms of Antibiotic Resistance Gene Enrichment by Microplastics in the Environment].

This review examines how microplastics in the environment serve as carriers for antibiotic resistance genes, enriching and spreading resistant bacteria across air, soil, water, and sediments. Researchers found that the type, surface characteristics, and aging of microplastics all influence how effectively they accumulate resistance genes and facilitate horizontal gene transfer. The findings highlight the need to consider microplastics as an important vector in the environmental spread of antibiotic resistance.

2026 PubMed
Article Tier 2

Microplastic biofilm as hotspots of antibiotic resistance genes and potential pathogens

This review examined how microplastic biofilms—the plastisphere—serve as hotspots for antibiotic resistance gene (ARG) accumulation and potential pathogen enrichment. The authors described mechanisms by which microplastic surfaces promote horizontal gene transfer and bacterial community shifts that favor ARG-carrying strains, raising concern that microplastics accelerate the spread of antibiotic resistance in aquatic environments.

2025 npj Biofilms and Microbiomes
Article Tier 2

Selectively enrichment of antibiotics and ARGs by microplastics in river, estuary and marine waters

Researchers investigated how microplastics interact with antibiotics and antibiotic resistance genes across river, estuary, and marine environments of varying salinity. They found that microplastics can concentrate both antibiotics and antibiotic resistance genes from surrounding water, with this enrichment effect being strongest in freshwater and decreasing as salinity increases. The study raises concerns that microplastics may serve as vehicles for spreading antibiotic resistance in aquatic ecosystems.

2019 The Science of The Total Environment 210 citations
Article Tier 2

Microplastics pollution in the ocean: Potential carrier of resistant bacteria and resistance genes

This review examined microplastics in marine environments as carriers of antibiotic-resistant bacteria and resistance genes, finding that plastic surfaces selectively enrich resistance genes through horizontal gene transfer and co-selection pressure, making ocean microplastics a vector for resistance dissemination across ecosystems.

2021 Environmental Pollution 96 citations
Article Tier 2

Microbubble-microplastic interactions in batch air flotation

Researchers explored the role of microplastics as carriers of antibiotic resistance genes in aquatic environments, finding that plastic surfaces harbor higher densities of resistance genes than surrounding water. Biofilm formation on microplastics appears to facilitate horizontal gene transfer.

2022 Chemical Engineering Journal 66 citations
Article Tier 2

Microplastic biofilm: An important microniche that may accelerate the spread of antibiotic resistance genes via natural transformation

Researchers discovered that biofilms forming on microplastics can accelerate the spread of antibiotic resistance genes through a process called natural transformation. They found that transformation rates on microplastic surfaces were up to 1,000 times higher than on natural substrates. The study suggests that microplastic pollution may create hotspots where bacteria more readily pick up and share genes for antibiotic resistance.

2023 Journal of Hazardous Materials 68 citations
Article Tier 2

Reshaping the antibiotic resistance genes in plastisphere upon deposition in sediment-water interface: Dynamic evolution and propagation mechanism

Researchers examined how antibiotic resistance genes in the microplastic biofilm (plastisphere) evolve as MPs settle from water to sediment, finding that deposition in sediment reshapes ARG profiles and promotes horizontal gene transfer, amplifying resistance gene reservoirs in benthic environments.

2025 Journal of Hazardous Materials 3 citations
Article Tier 2

Exploring the dynamics of antibiotic resistome on plastic debris traveling from the river to the sea along a representative estuary based on field sequential transfer incubations

Researchers tracked how antibiotic resistance genes change on plastic debris as it travels from a river through an estuary into the sea. They found that over 80 percent of resistance genes persisted on the plastic throughout the journey, and some genes found on the plastic were absent from the surrounding seawater. The study suggests that floating plastic waste could act as a vehicle for spreading antibiotic resistance from inland waterways into marine environments.

2024 The Science of The Total Environment 6 citations
Article Tier 2

Microplastics and Their Role in the Maintenance and Spread of Antibiotic Resistance Genes in Marine Ecosystems

This review examines the role of microplastics in maintaining and spreading antibiotic resistance genes in marine ecosystems, synthesizing evidence that plastic pollution in aquatic environments creates reservoirs for antimicrobial resistant bacteria and facilitates horizontal gene transfer.

2022 Antibiot Khimioter = Antibiotics and Chemotherapy 1 citations