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61,005 resultsShowing papers similar to Toxic Effects of Xenobiotics on Gut Microbiome and Host Health: A Mini-Review
ClearImpact of Cumulative Environmental and Dietary Xenobiotics on Human Microbiota: Risk Assessment for One Health
This review examines cumulative exposure to environmental and dietary xenobiotics including microplastics, pesticides, and food additives, assessing their combined impact on the human gut microbiome within a One Health risk framework.
Interactions between environmental pollutants and gut microbiota: A review connecting the conventional heavy metals and the emerging microplastics
This review examines how environmental pollutants, including both heavy metals and microplastics, interact with gut bacteria in humans and animals. The authors found that these pollutants can disrupt the balance of gut microbiota, which may contribute to various health problems, and that gut bacteria can also transform pollutants in ways that change their toxicity.
Research Advances on the Impact of Environmental Pollutants on Gut Microbiota
This review synthesizes evidence from animal models, human studies, and mechanistic experiments showing how microplastics, pesticides, and heavy metals each disrupt gut microbiota composition, reduce beneficial bacteria, and compromise intestinal barrier integrity and host health.
Influence of toxic metal exposure on the gut microbiota (Review)
This review summarized evidence on how heavy metals and toxic metals alter gut microbiota composition, diversity, and function, finding metal-specific effects depending on compound form, exposure route, and duration that complicate direct comparisons across studies.
Toxicological Evaluation of Effects of Some Environmental Pollutants on Intestinal Microbiota: Traditional Review
This review examines how various environmental pollutants affect the gut microbiome — the community of microorganisms in the intestinal tract. Microplastics are among the pollutants discussed, and their ability to alter gut microbiota composition is increasingly recognized as a mechanism by which plastic particles may harm human and animal health.
Effects of Environmental Exposure on Host and Microbial Metabolism
This collection of studies investigates how environmental exposures, including microplastics, PFAS, and other emerging pollutants, disrupt the gut microbiota and alter host metabolism. The research covers a wide spectrum of contaminants and examines how they affect the trillions of microorganisms in the gastrointestinal tract that play essential roles in human health. The findings suggest that environmental pollutants can drive metabolic changes by disrupting the balance between gut microbes and their human hosts.
Microplastics and the gut microbiome: Emerging health concerns and strategies
This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.
Role-Playing Between Environmental Pollutants and Human Gut Microbiota: A Complex Bidirectional Interaction
This review examined the bidirectional relationship between environmental pollutants, including microplastics, and the human gut microbiota, highlighting how toxicants alter microbial communities while gut bacteria can metabolize or modify pollutant toxicity.
Interactions between gut microbiota and emerging contaminants exposure: new and profound implications for human health
This review explores how emerging contaminants like microplastics, antibiotics, and persistent organic pollutants interact with gut bacteria and what that means for human health. Researchers found that the gut microbiome is a key target of these pollutants and may play a role in organ damage, hormonal disruption, and other toxic effects through pathways like the gut-liver and gut-brain axes. The study underscores the importance of understanding the three-way relationship between environmental contaminants, gut bacteria, and overall health.
Gut microbiota as an emerging target for the health implications of microplastics
This review examines how microplastic exposure disrupts the gut microbiome, finding evidence that microplastics damage intestinal barrier proteins, promote inflammation and oxidative stress, and may drive systemic effects including neurotoxicity and reproductive toxicity through gut-mediated pathways.
Gut microbiota of aquatic organisms: A key endpoint for ecotoxicological studies
This review examines how environmental contaminants including microplastics, pesticides, heavy metals, and pharmaceuticals affect the gut microbiota of aquatic organisms. Researchers highlight that changes in gut bacterial communities can serve as sensitive indicators of pollution exposure and may have downstream effects on host fitness. The study calls for improved methodologies to better link contaminant-induced shifts in gut microbiota to measurable health outcomes in aquatic species.
The potential influence of food additives and contaminants on the gut microbiota: A comprehensive review
This comprehensive review examines how food additives and contaminants, including pesticides, heavy metals, microplastics, and antibiotics, affect the gut microbiota. Researchers found that these substances can disrupt the balance of gut microbes, leading to inflammation, gastrointestinal injury, and altered production of beneficial short-chain fatty acids. The study emphasizes the need for further research into the mechanisms by which dietary contaminants affect gut health and overall wellbeing.
Probiotics as Modulators of Microplastic-induced Toxicity: A Systematic Review
This systematic review found that probiotics can reduce microplastic-induced toxicity in animal models by restoring gut microbiota balance, reducing oxidative stress, and modulating inflammatory responses. The findings suggest that probiotic supplementation may help mitigate the harmful effects of unavoidable microplastic exposure, though human clinical trials are still needed.
Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health
This review explores how microplastics interact with microorganisms in the environment and within the gut, examining implications for both animal and human health. Researchers found that microplastics can alter gut microbiota composition, promote the spread of antibiotic-resistant bacteria, and amplify the toxicity of other environmental pollutants. The study suggests that the interaction between microplastics and gut microorganisms is an important emerging area for understanding health risks.
Micro(nano)plastics and their potential impact on human gut health: a narrative review
This narrative review synthesizes evidence on how microplastics and nanoplastics affect the human gut, discussing ingestion routes, gut barrier interactions, microbiome disruption, and potential systemic health effects.
A Bibliometric Analysis of Toxicological Impacts of Microplastics in the Environment.
This bibliometric analysis of microplastic toxicology research found exponential growth in gut health studies since 2016, highlighting rising concern over how microplastics — especially in combination with heavy metals — cause immunotoxicity, biofilm formation, and accumulation in human tissues.
The ant that may well destroy a whole dam: a systematic review of the health implication of nanoplastics/microplastics through gut microbiota
This systematic review summarizes existing research on how nanoplastics and microplastics disrupt gut bacteria in various organisms. The findings show that plastic particle exposure consistently alters gut microbiome composition, which in turn affects the host's immune function, metabolism, and overall health. These gut bacteria changes may be a key pathway through which microplastics harm human health.
Microplastics and their interactions with microbiota
This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.
Micro- and Nanoplastics as Emerging Environmental Materials: GreenChemistry Insights into Gut Microbiota Disruption and Chronic DiseasePathways
Researchers reviewed how micro- and nanoplastics accumulate in the gastrointestinal tract and disrupt gut microbiota composition, finding evidence linking these exposures to reduced microbial diversity, gut barrier dysfunction, systemic inflammation, and potential contributions to chronic diseases including metabolic disorders and neurodegeneration.
Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks
This review summarizes evidence that microplastics disrupt the gut microbiome, the community of bacteria in our digestive system that plays a key role in immunity, metabolism, and overall health. By altering gut bacteria balance and triggering inflammation, microplastic exposure may contribute to chronic conditions including inflammatory bowel disease, metabolic disorders, and potentially even neurological problems through the gut-brain connection.
Role of Gut Microbiota in Modulating Oxidative Stress Induced by Environmental Factors
This review examines how environmental pollutants, including microplastics, toxic metals, and antibiotics, disrupt the balance of gut bacteria and trigger oxidative stress throughout the body. The resulting gut dysbiosis impairs the production of beneficial molecules, weakens the intestinal barrier, and activates inflammatory pathways linked to chronic disease. The review also discusses therapeutic interventions like probiotics and polyphenols that may help restore gut health and counteract pollutant-driven damage.
Toxic and essential metals: metabolic interactions with the gut microbiota and health implications
This review summarizes how toxic heavy metals like lead, mercury, and cadmium interact with gut bacteria in ways that affect both metal absorption and overall health. While not directly about microplastics, the findings are relevant because microplastics are known to carry heavy metals into the body, and gut bacteria play a key role in determining how much of those metals are absorbed.
The role of gut microbiota in MP/NP-induced toxicity
This review summarizes how micro- and nanoplastics disrupt gut bacteria and why that matters for overall health. The tiny plastic particles change the composition and function of the gut microbiome, which can trigger inflammation, weaken the intestinal barrier, and potentially contribute to diseases beyond the gut through the immune and nervous systems.
Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review
This review summarizes research on how micro- and nanoplastics affect the gut, finding that they can damage the intestinal lining, trigger immune responses, and disrupt the balance of beneficial gut bacteria in both cell studies and animal models. Since humans are primarily exposed to microplastics through food and food packaging, understanding these gut effects is essential for assessing the true health risks of plastic pollution.