Papers

61,005 results
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Article Tier 2

Interactions between microplastics and phthalate esters as affected by microplastics characteristics and solution chemistry

The sorption of two phthalate esters onto polystyrene, polyethylene, and polypropylene microplastics was studied under varying conditions, finding that sorption was influenced by polymer type, phthalate structure, temperature, salinity, and dissolved organic matter. The results provide mechanistic insight into how microplastics accumulate endocrine-disrupting phthalates from the environment.

2018 Chemosphere 278 citations
Article Tier 2

Environmental occurrence and ecotoxicological risks of plastic leachates in aquatic and terrestrial environments

This review examines how chemical additives that leach out of plastics -- including hormone disruptors like BPA and phthalates -- affect organisms in both water and land environments. The chemicals' harmful effects depend on environmental conditions like temperature and UV exposure, which influence how much leaches out and how easily organisms absorb it. The findings highlight that the danger of plastic pollution extends beyond the physical particles to the toxic chemicals they release.

2024 The Science of The Total Environment 36 citations
Article Tier 2

Microplastics: A major source of phthalate esters in aquatic environments

Researchers demonstrated that microplastics are a major source of phthalate esters in aquatic environments, with PVC products leaching the highest concentrations and environmental factors like UV exposure and salinity increasing release rates.

2022 Journal of Hazardous Materials 172 citations
Article Tier 2

Toxicological interactions of microplastics/nanoplastics and environmental contaminants: Current knowledge and future perspectives

This review examines how the combined presence of micro- and nanoplastics with other environmental contaminants like heavy metals, pesticides, and pharmaceuticals affects toxicity. Researchers found that plastic particles can alter the bioavailability and toxic effects of co-occurring pollutants, sometimes increasing harm to organisms, which complicates environmental risk assessment.

2020 Journal of Hazardous Materials 501 citations
Article Tier 2

From co-occurrence to co-existence and co-exposure: Associations between per- and polyfluoroalkyl substances and microplastics in the environment

This review examines the growing recognition that PFAS chemicals and microplastics frequently co-occur in the environment and may interact in ways that affect both ecological and human health. Researchers identified four major sources that emit both pollutants simultaneously and found strong evidence that PFAS can adsorb onto microplastic surfaces and be co-transported through the environment. The study calls for standardized methods and long-term studies to better understand the combined exposure risks of these two widespread contaminant classes.

2025 Journal of Hazardous Materials 2 citations
Article Tier 2

Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut

Researchers investigated whether microplastics can transport and release phthalate esters (PAEs) into the mouse gut, finding that microplastics adsorbed PAEs and carried them into the intestine where they accumulated. The study suggests that microplastics acting as carriers for chemical contaminants may aggravate adverse health effects in the gut beyond what either pollutant causes alone.

2020 Environment International 299 citations
Article Tier 2

Phthalate acid ester release from microplastics in water environment and their comparison between single and competitive adsorption

Microplastics release phthalate plasticizers (PAEs) into water, and this study found that release rates and adsorption behavior differ significantly between polyethylene, polypropylene, and polystyrene particles, with temperature, pH, and salinity all affecting how much chemical leaches out. When multiple PAEs were present simultaneously, competitive adsorption reduced the uptake of individual chemicals — important context for understanding the real-world chemical exposure that aquatic organisms and humans face from microplastic-contaminated water.

2023 Environmental Science and Pollution Research 14 citations
Article Tier 2

Environmental Co-existence of Microplastics and Perfluorochemicals: A Review of Their Interactions

This review examines how microplastics and perfluorochemicals, two widespread pollutant classes, interact when they coexist in the environment. Researchers found that microplastics can adsorb perfluorochemicals onto their surfaces, potentially altering how both pollutants move through ecosystems and affect organisms. The study highlights that the combined presence of these contaminants may pose greater environmental risks than either one alone.

2023 Biointerface Research in Applied Chemistry 15 citations
Systematic Review Tier 1

Environmental behaviors of microplastics in aquatic systems: A systematic review on degradation, adsorption, toxicity and biofilm under aging conditions

Aging processes like UV irradiation and physical abrasion alter microplastic surface properties, increasing their capacity to adsorb environmental pollutants while also enhancing leaching of toxic additives like phthalates, collectively amplifying the environmental toxicity of weathered microplastics.

2021 Journal of Hazardous Materials 560 citations
Article Tier 2

A critical review on the interaction of polymer particles and co-existing contaminants: Adsorption mechanism, exposure factors, effects on plankton species

This review critically examines how microplastics and nanoplastics interact with co-existing contaminants including organic pollutants, toxic metals, and nanoparticles. Researchers found that the combined toxicity depends on multiple factors including plastic size, polymer type, weathering, and the nature of the co-contaminant. The study reveals that mixture effects on plankton species vary widely, with some combinations producing synergistic harm and others showing antagonistic interactions.

2022 Journal of Hazardous Materials 64 citations
Article Tier 2

Fate of microplastics and emerging contaminants: Mechanisms of interactions, bioaccumulation and combined toxicity to aquatic organisms

This review summarizes how microplastics interact with other emerging contaminants in water, finding that microplastics can absorb pollutants at concentrations up to a million times higher than surrounding water and carry them into living organisms. The combined toxicity of microplastics plus these hitchhiking chemicals is often greater than either alone, and these pollutants can reach humans through the food chain.

2025 Marine Pollution Bulletin 11 citations
Article Tier 2

Microplastics and associated emerging contaminants in the environment: Analysis, sorption mechanisms and effects of co-exposure

Researchers reviewed how microplastics act as carriers for other environmental pollutants — including antibiotics, PFAS, and triclosan — absorbing them from surrounding water and potentially delivering higher doses to organisms that ingest the plastic, with combined toxicity effects that can be either amplified or reduced depending on the combination.

2022 Trends in Environmental Analytical Chemistry 151 citations
Article Tier 2

A review on the combined toxicological effects of microplastics and their attached pollutants

Researchers reviewed how microplastics act as carriers for other environmental pollutants — including heavy metals and persistent organic chemicals — and how these combinations produce toxic effects in organisms that are more severe than either contaminant alone. The findings highlight a complex, layered toxicity problem that affects microbes, invertebrates, and vertebrates across marine and terrestrial environments.

2025 Emerging contaminants 20 citations
Article Tier 2

Interaction of Environmental Pollutants with Microplastics: A Critical Review of Sorption Factors, Bioaccumulation and Ecotoxicological Effects

This critical review examines how microplastics interact with and enhance the toxicity of co-occurring environmental pollutants including heavy metals, persistent organic compounds, and pharmaceuticals, synthesizing evidence on sorption mechanisms and combined ecotoxicological effects.

2020 Toxics 313 citations
Article Tier 2

Contaminant occurrence, distribution and ecological risk assessment of phthalate esters in the Persian Gulf

This study measured phthalate esters, chemicals commonly used as plastic softeners, in water samples from the Persian Gulf and assessed their ecological risk. Several phthalate compounds were detected at levels that pose potential risks to aquatic organisms. These chemicals are classified as endocrine disruptors and possible carcinogens, and since they leach from microplastics in water, their presence highlights how plastic pollution can introduce harmful chemicals into marine environments and the seafood supply.

2023 PLoS ONE 31 citations
Article Tier 2

Interaction of toxic chemicals with microplastics: A critical review

This critical review examined how toxic chemicals interact with microplastics in the environment, synthesizing evidence on adsorption, desorption, and the conditions under which microplastics either increase or decrease the bioavailability of co-occurring pollutants.

2018 Water Research 875 citations
Article Tier 2

Toxicity of polyethylene terephthalate microplastics and dimethyl phthalate in male Sprague-Dawley rats: Insights into oxidative stress, DNA damage, and histopathological impacts

Researchers exposed male rats to polyethylene terephthalate microplastics and dimethyl phthalate, a common plasticizer, both individually and in combination over 28 days. The co-exposure group showed significantly elevated markers of oxidative DNA damage, severe liver tissue degeneration, and liver enlargement compared to controls. The study highlights the potential for synergistic health effects when microplastics and their associated chemical additives are encountered together.

2025 Chemosphere 1 citations
Article Tier 2

Mixtures of Micro and Nanoplastics and Contaminants of Emerging Concern in Environment: What We Know about Their Toxicological Effects

This review examines what is known about the toxicological effects of micro- and nanoplastic mixtures combined with other emerging contaminants in the environment. Researchers found that most studies fail to calculate proper interaction parameters, making it difficult to determine whether combined exposures produce additive, synergistic, or antagonistic effects on organisms.

2024 Toxics 14 citations
Article Tier 2

A tale of two emerging contaminants: Interfacial interactions, co-transport behaviors and ecotoxicological implications between per-and polyfluoroalkyl substances and micro(nano)plastics.

This review examined how PFAS and micro/nanoplastics co-occur in the environment, form interfacial adsorption complexes, and interact synergistically within organisms. The authors found that the two contaminant classes amplify each other's toxicity in co-exposure scenarios and that their shared transport pathways complicate standard risk assessment.

2026 Advances in colloid and interface science
Article Tier 2

Combined Environmental Impacts and Toxicological Interactions of Per- and Polyfluoroalkyl Substances (PFAS) and Microplastics (MPs)

This review examines how microplastics and per- and polyfluoroalkyl substances (PFAS) frequently co-occur in the environment and interact to alter each other's environmental fate and biological effects. Researchers found that co-exposure can enhance PFAS bioaccumulation by up to 2.5-fold compared to PFAS alone, accompanied by amplified oxidative stress, immune disruption, and reproductive impairment in aquatic organisms. The magnitude and direction of combined effects depend heavily on polymer type, particle size, surface aging, and biological context.

2026 Environments
Article Tier 2

Plastic and Microplastic Wastes as Environmental Toxicants

This review covers the environmental accumulation of plastics and microplastics and their toxic chemical additives — including phthalates, flame retardants, bisphenol A, heavy metals, and PCBs — documenting contamination from urban regions to remote ecosystems and food/water supplies.

2024 1 citations
Article Tier 2

Combined ecotoxicity of polystyrene microplastics and Di-(2-ethylhexyl) phthalate increase exposure risks to Mytilus coruscus based on the bioaccumulation, oxidative stress, metabolic profiles, and nutritional interferences

Researchers exposed hard-shelled mussels to a common plastic additive (DEHP) and polystyrene microplastics together, and found that the microplastics increased how much DEHP accumulated in the animals' digestive organs. The combined exposure disrupted the mussels' antioxidant defenses and altered their metabolic processes more than either pollutant alone. The study suggests that microplastics can amplify the harmful effects of chemical pollutants in marine organisms.

2024 Journal of Hazardous Materials 6 citations
Article Tier 2

Leaching kinetics and bioaccumulation potential of additive-derived organophosphate esters in microplastics

Researchers studied the leaching kinetics of organophosphate ester additives from microplastics in aquatic environments, finding that these flame retardants and plasticizers are released at rates that depend on temperature and water chemistry, with implications for bioaccumulation in aquatic organisms.

2024 Environmental Pollution 9 citations
Article Tier 2

Single and joint exposure to nanoplastics and bisphenols: a comparative assessment of in vitro hazards

This study compared the individual and combined toxicity of nanoplastics and bisphenol compounds in biological test systems, finding synergistic effects at certain exposure combinations. The results indicate that co-exposure to these two common plastic-associated contaminants may be more harmful than either alone.

2024 Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)