Papers

20 results
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Article Tier 2

Melatonin-Mediated Abiotic Stress Tolerance in Plants

This review examines how melatonin, a molecule found in all living organisms, helps plants cope with environmental stresses like drought, extreme temperatures, salinity, and heavy metal contamination. Researchers found that melatonin works by neutralizing harmful reactive oxygen species and activating plant defense pathways. The study suggests that melatonin-based treatments could help improve crop resilience in the face of increasing environmental challenges, including soil pollution.

2022 Frontiers in Plant Science 149 citations
Article Tier 2

Melatonin enhances salt tolerance in sorghum by modulating photosynthetic performance, osmoregulation, antioxidant defense, and ion homeostasis

Exogenous melatonin application was found to enhance salt tolerance in sorghum by improving photosynthetic performance and modulating antioxidant responses during salt stress. The findings suggest melatonin could be a practical tool for improving crop resilience under salinity conditions.

2023 Open Life Sciences 25 citations
Article Tier 2

Involvement of Nitric Oxide and Melatonin Enhances Cadmium Resistance of Tomato Seedlings through Regulation of the Ascorbate–Glutathione Cycle and ROS Metabolism

Researchers found that melatonin and nitric oxide work together to enhance cadmium stress tolerance in tomato seedlings, with melatonin acting partly through nitric oxide signaling to reduce oxidative damage and support seedling growth under heavy metal stress.

2023 International Journal of Molecular Sciences 25 citations
Article Tier 2

Synergistic integration of melatonin, copper nanoparticles, and Bacillus velezensis mitigates anthracnose and microplastic stress in chili: A novel eco-friendly strategy for sustainable crop protection

Researchers combined melatonin, copper nanoparticles, and a beneficial bacterium (Bacillus velezensis) to simultaneously protect chili pepper plants from both fungal disease and microplastic stress, finding the triple treatment restored photosynthesis, hormone balance, and antioxidant defenses better than any single agent alone.

2025 Journal of Hazardous Materials
Article Tier 2

Exogenous Melatonin Application Alleviates Microplastics and Cadmium‐Induced Phytotoxicity in Maize ( Zea mays L.) Plants: Insights From Physiological and Metabolomic Analyses

Researchers investigated whether exogenous melatonin could alleviate the combined phytotoxicity of microplastics and cadmium in maize plants. The study found that melatonin application reduced oxidative damage and improved plant growth under co-contamination stress, suggesting that melatonin may serve as a biostimulant to help crops cope with the increasingly common co-occurrence of microplastics and heavy metals in agricultural soils.

2025 Journal of Pineal Research 1 citations
Article Tier 2

Melatonin Alleviates Antimony Toxicity by Regulating the Antioxidant Response and Reducing Antimony Accumulation in Oryza sativa L.

Researchers investigated whether melatonin, a natural antioxidant compound, could help rice plants cope with toxic antimony contamination. They found that applying melatonin reduced antimony uptake, decreased oxidative damage, and improved rice growth under antimony stress conditions. The study suggests that melatonin treatments could be a practical strategy for growing rice in soils contaminated with heavy metals.

2023 Antioxidants 22 citations
Article Tier 2

Reclaiming multi-contaminated soil: melatonin alleviates cadmium and microplastic toxicity to restore rice growth and yield

Researchers investigated whether melatonin could mitigate the combined toxicity of cadmium and microplastics in agricultural soils to restore rice growth and yield. The study found that melatonin treatment modulated plant physiological function, reduced cadmium uptake, and improved soil properties, offering a promising approach to help crops withstand multi-contaminant stress from both heavy metals and microplastics.

2026 RSC Advances
Article Tier 2

Melatonin reduces nanoplastic uptake, translocation, and toxicity in wheat

Researchers investigated whether melatonin could reduce the harmful effects of polystyrene nanoplastics on wheat plants. They found that melatonin application significantly decreased nanoplastic uptake by roots and their transport to shoots by regulating aquaporin gene expression and activating antioxidant defense systems. The study suggests that melatonin may serve as a protective agent to help mitigate nanoplastic toxicity in crops.

2021 Journal of Pineal Research 75 citations
Article Tier 2

Melatonin Defends Against the Oxidative Stress by Preventing the Uptake of Nanoplastics and Activating the Antioxidant System in Paeonia ostii.

Scientists found that melatonin (a natural hormone) can protect plants from tiny plastic particles by blocking them from entering plant cells and reducing harmful damage inside the plant. This matters because these microscopic plastics are spreading everywhere in our environment and getting into our food chain. While this study only looked at plants, it suggests melatonin might help protect living things from plastic pollution - though more research is needed to know if this applies to humans.

2026 PubMed
Article Tier 2

Titanium dioxide nanoparticles alleviates polystyrene nanoplastics induced growth inhibition by modulating carbon and nitrogen metabolism via melatonin signaling in maize

Researchers found that titanium dioxide nanoparticles can help protect maize plants from the growth-inhibiting effects of polystyrene nanoplastics. The protective mechanism works through the plant hormone melatonin, which regulates carbon and nitrogen metabolism when the nanoparticles are present. The study suggests that certain nanoparticles could potentially be used as agricultural tools to help crops cope with nanoplastic contamination in soil.

2024 Journal of Nanobiotechnology 29 citations
Article Tier 2

Melatonin induces endoreduplication through oxidative DNA-damage triggering lateral root formation in onions

This study found that melatonin triggers lateral root formation in onions by inducing DNA damage and endoreduplication. Plant hormone research is relevant to microplastics because microplastics in soil can disrupt plant hormone signaling and root development in food crops.

2023 2 citations
Article Tier 2

Ectopic Expression of AeNAC83, a NAC Transcription Factor from Abelmoschus esculentus, Inhibits Growth and Confers Tolerance to Salt Stress in Arabidopsis

Researchers found that the NAC transcription factor AeNAC83 from okra inhibits plant growth while conferring salt stress tolerance in Arabidopsis, with gene silencing increasing biomass but reducing salt resistance, revealing a growth-stress tolerance trade-off mediated by this transcription factor.

2022 International Journal of Molecular Sciences 21 citations
Article Tier 2

Unraveling the Complex Physiological, Biochemical, and Transcriptomic Responses of Pea Sprouts to Salinity Stress

Researchers investigated the physiological, biochemical, and transcriptomic responses of pea sprouts to high salinity stress, analyzing the ascorbic acid-glutathione cycle, endogenous hormone levels, metabolite profiles, and gene expression patterns. The study revealed coordinated redox-metabolic adjustments and transcriptome reprogramming that mediate ionic stress tolerance in this nutrient-rich crop.

2025 Genes
Article Tier 2

Deciphering Pesticide Stress Responses in Rice Through Integrated Multi-Omic Assessment

This review synthesizes research on how pesticide exposure affects rice plants at the molecular level, drawing on transcriptomic, proteomic, and metabolomic studies. Researchers found that pesticides trigger detoxification enzymes, alter antioxidant defenses, and reprogram metabolic pathways in rice. The study highlights how integrating multiple omics approaches can provide a more complete picture of pesticide stress responses in crops.

2026 Toxics
Article Tier 2

Genome-Wide Identification of β-Ketoacyl CoA Synthase Gene Family in Melon (Cucumis melo L.) and Its Expression Analysis in Autotoxicity, Saline-Alkali, and Microplastic Exposure Environments

Researchers identified the gene family responsible for producing long-chain fatty acids in melon plants and studied how these genes respond to microplastic exposure and other stresses. They found that specific genes were activated or suppressed when plants encountered microplastics, saline-alkali conditions, or soil toxins from previous crops. The study provides insights into how food crops defend themselves at the genetic level against environmental contaminants including microplastics.

2025 Current Issues in Molecular Biology 2 citations
Article Tier 2

New Insight on the In Vitro Effects of Melatonin in Preserving Human Sperm Quality

Researchers found that melatonin protects human sperm quality against cadmium-induced oxidative stress in vitro, preserving motility, viability, DNA integrity, and mitochondrial function while reducing lipid peroxidation over 24 hours of exposure.

2022 International Journal of Molecular Sciences 24 citations
Article Tier 2

Exogenous spermine alleviates the negative effects of combined salinity and paraquat in tomato plants by decreasing stress-induced oxidative damage

Exogenous spermine application reduced leaf damage and improved photosynthetic function and growth of tomato plants under combined salinity and paraquat herbicide stress, with the protective effect attributed to decreased hydrogen peroxide and malondialdehyde accumulation.

2023 Frontiers in Plant Science 24 citations
Article Tier 2

Integrative Physiological and Transcriptome Analysis Reveals the Mechanism of Cd Tolerance in Sinapis alba

This paper is not about microplastics; it uses transcriptomics and physiological measurements to understand how white mustard (Sinapis alba) tolerates cadmium heavy metal stress at the molecular level.

2023 Genes 6 citations
Article Tier 2

Metabolic Profiling of Sugars and Organic Acids, and Expression Analyses of Metabolism-Associated Genes in Two Yellow-Peel Pitaya Species

Researchers profiled sugar and organic acid metabolism across fruit developmental stages in two yellow-peel pitaya species ('WCHL' Hylocereus undatus and 'YCHL' Hylocereus megalanthus), using metabolic and gene expression analyses to track accumulation of phenols, flavonoids, ascorbic acid, starch, and soluble sugars. The study identifies species-specific patterns in metabolite accumulation and associated gene expression that determine pitaya fruit quality.

2022 Plants 18 citations
Article Tier 2

Melatonin Supplementation during In Vitro Maturation of Porcine Oocytes Alleviates Oxidative Stress and Endoplasmic Reticulum Stress Induced by Imidacloprid Exposure

Researchers found that the neonicotinoid insecticide imidacloprid adversely affected porcine oocyte maturation by increasing oxidative stress, endoplasmic reticulum stress, and apoptosis. The study demonstrated that melatonin supplementation during in vitro maturation was able to restore oocyte quality and embryo development outcomes compromised by imidacloprid exposure, suggesting melatonin has protective properties against pesticide-induced reproductive toxicity.

2023 Animals 11 citations