Papers

20 results
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Article Tier 2

Effects of nanoplastic on cell apoptosis and ion regulation in the gills of Macrobrachium nipponense

Researchers exposed juvenile oriental river shrimp to varying concentrations of nanoplastics and examined effects on gill cell viability and ion regulation. They found that higher nanoplastic concentrations increased cell death rates, decreased ion content, reduced ATPase enzyme activity, and disrupted ion transport gene expression in gill tissues. The study suggests that nanoplastic pollution can impair critical ion regulation functions in freshwater crustaceans, with implications for aquaculture.

2022 Environmental Pollution 51 citations
Article Tier 2

Transcriptomic analysis following polystyrene nanoplastic stress in the Pacific white shrimp, Litopenaeus vannamei

Researchers used transcriptomic analysis to study how polystyrene nanoplastics affect gene expression in Pacific white shrimp. They found that nanoplastic exposure activated lysosome pathways and disrupted genes involved in immune response, protein processing, and metabolism. The study provides molecular-level evidence that nanoplastics can interfere with multiple biological systems in commercially important shrimp species.

2023 Fish & Shellfish Immunology 15 citations
Article Tier 2

Revealing the Impact of Polystyrene Nanoplastics on Gill Tissues of the Intertidal Clam, Gafrarium Divaricatum (Gmelin, 1791) using Transcriptomics Approach

Researchers exposed intertidal clams to polystyrene nanoplastics and used transcriptomics to assess gill tissue impacts, finding 1,182 upregulated and 1,626 downregulated genes related to immune modulation, antioxidant defense, and apoptosis. Histopathological examination revealed structural damage to gill tissues including ciliary erosion, lamellae fusion, and lipofuscin accumulation. The study establishes a high-quality genomic resource for this clam species while demonstrating the ecotoxicological effects of nanoplastics on sessile marine bivalves.

2026 Marine Biotechnology
Article Tier 2

Effects of exposure to nanoplastics on the gill of mussels Mytilus galloprovincialis: An integrated perspective from multiple biomarkers

Researchers exposed Mediterranean mussels to polystyrene nanoplastics for seven days and measured multiple gill biomarkers, finding that nanoplastics triggered oxidative stress, inhibited acetylcholinesterase, disrupted sodium-potassium ion transport, and impaired energy and lipid metabolism, pointing to broad physiological interference in marine invertebrates.

2023 Marine Environmental Research 14 citations
Article Tier 2

Toxicological effects of microplastics in Litopenaeus vannamei as indicated by an integrated microbiome, proteomic and metabolomic approach

Shrimp (Litopenaeus vannamei) exposed to five microplastic types for 14 days showed gut microbiota shifts (increased Bacteroidetes and Proteobacteria, decreased Firmicutes) and altered haemolymph proteomes, with each MP type producing distinct immune pathway effects.

2020 The Science of The Total Environment 97 citations
Article Tier 2

Effects of microplastics on gene expression to nonspecific immune system in pacific white shrimp (Litopenaeus vannamei).

This study found that high-density polyethylene microplastic particles in shrimp feed suppressed immune defense genes in Pacific white shrimp and caused intestinal and gill tissue damage at concentrations well below lethal levels. The findings suggest that microplastic exposure could compromise immune function and health in farmed crustaceans.

2022 1 citations
Article Tier 2

Oxidative effects of consuming microplastics in different tissues of white shrimp Litopenaeus vannamei

Researchers fed white shrimp diets containing polystyrene microplastics and found the particles accumulated in gills, muscles, and the hepatopancreas. The microplastics triggered oxidative stress, DNA damage, and lipid damage in multiple tissues, along with visible tissue abnormalities including edema and immune cell infiltration. The study demonstrates that dietary microplastic exposure can cause widespread oxidative harm across different organ systems in commercially important shellfish.

2023 Marine Pollution Bulletin 22 citations
Article Tier 2

Insight into the immune and microbial response of the white-leg shrimp Litopenaeus vannamei to microplastics

Researchers exposed white-leg shrimp (Litopenaeus vannamei) to different concentrations of microplastics for 48 hours and measured immune and microbial responses. The study found that high microplastic concentrations significantly reduced survival rates, altered immune-related gene expression, and disrupted the gut microbial community, suggesting that microplastic pollution may compromise shrimp immune function.

2021 Marine Environmental Research 51 citations
Article Tier 2

Evaluation of nanoplastics toxicity in the soil nematode Caenorhabditis elegans by iTRAQ-based quantitative proteomics

Researchers used quantitative proteomics to evaluate nanoplastic toxicity in the nematode C. elegans, identifying disrupted proteins involved in oxidative stress, metabolism, and cellular defense pathways, providing molecular-level insight into how nanoplastics harm organisms.

2022 The Science of The Total Environment 21 citations
Article Tier 2

Transcriptional response in the whiteleg shrimp (Penaeus vannamei) to short-term microplastic exposure

Researchers exposed whiteleg shrimp (Penaeus vannamei) to microplastics for 96 hours and used transcriptomics to profile gene expression changes, finding significant upregulation of stress response, immune, and detoxification pathways, indicating that even short-term microplastic exposure triggers a broad molecular stress response.

2021 Aquaculture Reports 26 citations
Article Tier 2

Transcriptomic analysis reveals nanoplastics-induced apoptosis, autophagy and immune response in Litopenaeus vannamei

Shrimp exposed to polystyrene nanoplastics for 28 days showed dose-dependent damage to their immune systems, including increased cell death, tissue destruction in the liver-like organ, and disrupted antioxidant defenses. At high concentrations, the nanoplastics overwhelmed the shrimp's ability to fight off threats. Since shrimp are an important food source, these findings raise concerns about the quality and safety of seafood from nanoplastic-contaminated waters.

2024 The Science of The Total Environment 10 citations
Article Tier 2

Gradual effects of gradient concentrations of polystyrene nanoplastics on metabolic processes of the razor clams

Researchers exposed razor clams to a gradient of polystyrene nanoplastic concentrations and used metabolomics to track effects, finding that even low concentrations disrupted energy metabolism and amino acid pathways, with effects becoming more severe as concentration increased.

2021 Environmental Pollution 47 citations
Article Tier 2

Toxicity of Ammonia Stress on the Physiological Homeostasis in the Gills of Litopenaeus vannamei under Seawater and Low-Salinity Conditions

This study examined how ammonia stress damages the gills of Pacific white shrimp raised in both seawater and low-salinity conditions. While not directly about microplastics, the findings are relevant because microplastics in aquaculture water can worsen ammonia toxicity, and the gill damage observed -- including disrupted ion balance and immune function -- highlights how environmental stressors compound threats to seafood safety.

2024 Biology 20 citations
Article Tier 2

Effect of polyethylene microplastics on oxidative stress and histopathology damages in Litopenaeus vannamei

Researchers injected fluorescent polyethylene microspheres into Pacific white shrimp (Litopenaeus vannamei) and found that microplastic exposure increased oxidative stress markers and caused histopathological damage to hepatopancreas and gill tissue, even at relatively low concentrations.

2021 Environmental Pollution 122 citations
Article Tier 2

Toxicological effects of polystyrene nanoplastics on marine organisms

Researchers exposed Pacific white shrimp to polystyrene nanoplastics at various concentrations and measured immune, antioxidant, and tissue responses after seven days. They found that nanoplastic exposure disrupted immune function, increased oxidative stress, and caused tissue damage, particularly in the hepatopancreas and gills. The study adds to growing evidence that nanoplastics can harm the health of commercially important marine species.

2023 Environmental Technology & Innovation 32 citations
Article Tier 2

Microplastic toxicity in shrimp: From mechanistic pathways to ecological implications.

Researchers systematically reviewed 94 studies on microplastic toxicity in shrimp, mapping mechanistic pathways from particle characteristics to oxidative stress, immune dysfunction, neurotoxicity, and reproductive impairment across hepatopancreas, gills, gut, and gonad tissues, and identifying shrimp as effective bioindicators for aquatic microplastic risk assessment.

2026 Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
Article Tier 2

Use of Tandem Mass Spectrometry Quantitative Proteomics to Identify Potential Biomarkers to Follow the Effects of Cold and Frozen Storage of Muscle Tissue of Litopenaeus vannamei

Not directly relevant to microplastics — this study uses quantitative proteomics to identify protein biomarkers of quality deterioration in Pacific white shrimp muscle during cold and frozen storage.

2023 Foods 2 citations
Article Tier 2

Zebrafish exposure to high-density polyethylene and polystyrene microplastics: effects on liver transcriptome and gastrointestinal histology

This study used proteomics — the analysis of all proteins expressed by cells — to identify how zebrafish respond to exposure to high-density polyethylene and polystyrene microplastics, finding disruption of proteins involved in metabolism, oxidative stress, and immune defense. The protein-level analysis complements genomic approaches and reveals the biological mechanisms underlying microplastic toxicity in fish.

2018 Use Siena air (University of Siena)
Article Tier 2

Ecotoxicoproteomic assessment of microplastics and plastic additives in aquatic organisms: A review

This review examines how proteomics — the large-scale study of proteins — is being applied to understand the toxic effects of microplastics and plastic additives on aquatic organisms, and how this data can feed into adverse outcome pathway frameworks for ecological risk assessment.

2020 Comparative Biochemistry and Physiology Part D Genomics and Proteomics 97 citations
Article Tier 2

Polystyrene nanoplastics induce lipid metabolism disorder and alter fatty acid composition in the hepatopancreas of Pacific whiteleg shrimp (Litopenaeus vannamei)

Researchers exposed Pacific whiteleg shrimp to different concentrations of polystyrene nanoplastics for 28 days and found significant disruption to fat metabolism in the shrimp's digestive organ. Higher concentrations caused tissue damage, reduced protein and fat content, and altered the activity of enzymes that control how the body processes fats. Since shrimp is a widely consumed seafood, these findings raise questions about how nanoplastic contamination in aquaculture could affect the nutritional quality and safety of shellfish for human consumption.

2023 The Science of The Total Environment 30 citations