Papers

61,005 results
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Article Tier 2

MultigenerationalEffects of Weathered PolyethyleneMicroplastics on Drosophila melanogaster

Researchers tracked multigenerational effects of weathered polyethylene microplastics on Drosophila melanogaster, finding that fitness effects including reduced fecundity and lifespan became more pronounced in later generations even when offspring were not directly exposed.

2025 Figshare
Article Tier 2

Transgenerational effects on development following microplastic exposure in Drosophila melanogaster

Researchers fed Drosophila melanogaster flies plastic-supplemented food and found that while treated flies showed changes in fertility and sex ratio, their unexposed offspring had shorter larval development and reduced adult size, demonstrating transgenerational developmental effects from parental microplastic exposure.

2021 PeerJ 41 citations
Article Tier 2

No Effect of Realistic Microplastic Exposure on Growth and Development of Wild-caught Culex (Diptera: Culicidae) Mosquitoes

Researchers exposed wild-caught Culex mosquito larvae to polystyrene microplastics at environmentally realistic concentrations. The study found no significant effects on body size, development time, or growth rate in either species tested, suggesting that microplastic levels typically found in nature may have minimal impact on these fitness-related traits in mosquitoes.

2023 Journal of Medical Entomology 16 citations
Article Tier 2

The effects of nano- and microplastic ingestion on the survivorship and reproduction of Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

Researchers studied how nano- and microplastic ingestion affects survivorship and reproduction in small invertebrates, finding that exposure reduced reproductive output and survival rates in a dose-dependent manner. The results suggest that even environmentally relevant concentrations of plastic particles can impair fitness in aquatic invertebrates.

2024 Environmental Entomology 4 citations
Article Tier 2

A mini review on exposure of microplastic to Drosophila melanogaster causing sex-specific, transgenerational, locomotory, physiological and developmental effect

This mini-review synthesized studies on how polystyrene and PET microplastics affect Drosophila melanogaster across multiple biological levels including sex-specific responses, physiology, behavior, development, and transgenerational effects. Male Drosophila showed greater sensitivity to microplastics with higher mortality, and effects were both concentration- and size-dependent.

2024 Journal of Entomological Research 1 citations
Article Tier 2

Adverse biological effects of ingested polystyrene microplastics using Drosophila melanogaster as a model in vivo organism

Researchers used fruit flies as an in vivo model to study the biological effects of ingesting polystyrene microplastics at three different sizes. Exposure caused significant morphological defects, impaired climbing behavior, and genotoxic effects as shown by a somatic mutation test. The findings suggest that polystyrene microplastics may induce genetic damage primarily through somatic recombination, raising concerns about their potential biological impact on living organisms.

2021 Journal of Toxicology and Environmental Health 61 citations
Article Tier 2

Microplastic ingestion perturbs the microbiome of Aedes albopictus and Aedes aegypti

Researchers exposed Aedes aegypti and Aedes albopictus mosquito larvae to polystyrene microplastics and found that ingestion altered adult emergence rates, caused gut tissue damage, and disrupted the gut microbiome, demonstrating that microplastic contamination can impair mosquito development.

2023 Research Square (Research Square) 3 citations
Article Tier 2

The multigenerational effects of nanoplastic exposure on fitness and oxidative stress of Drosophila melanogaster

Researchers tracked the effects of nanoplastic exposure on fitness and oxidative stress markers across multiple generations of a small aquatic invertebrate. Reproductive success and antioxidant defenses deteriorated progressively across generations, suggesting that multigenerational exposure to nanoplastics causes cumulative ecological harm.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Tracking micro- and nanoplastics in Aedes albopictus: From ingestion to metabolic disruption

Researchers tracked the fate of polystyrene micro- and nanoplastics in the Asian tiger mosquito Aedes albopictus from larval ingestion through adult development. They found that ingested particles crossed the gut barrier, persisted in tissues, and were retained through metamorphosis, while causing reduced body weight and significant metabolic disruptions. The study suggests that plastic pollution may affect mosquito biology through endocrine disruption and altered energy metabolism pathways.

2025 The Science of The Total Environment 1 citations
Article Tier 2

Exposure of polystyrene microplastics induces oxidative stress and physiological defects in Drosophila melanogaster

Researchers used fruit flies as a model organism to study the effects of polystyrene microplastics and found that dietary exposure caused significant oxidative stress at both tested concentrations. The microplastics impaired climbing ability in adult flies and disrupted normal development patterns during the pupal stage. The study suggests that microplastic ingestion can trigger oxidative damage and physiological defects even in relatively simple organisms.

2024 Asian Journal of Basic Science & Research 3 citations
Article Tier 2

Microplastics on the menu; exploring interactions between two mosquitoes species and microplastics

Researchers exposed larvae of two mosquito species with contrasting feeding ecologies (Anopheles gambiae and Aedes albopictus) to varying concentrations, sizes, and densities of polystyrene and polyethylene microplastics, finding that ingestion risk was primarily determined by particle size rather than larval ecology, and that microplastics affected survival only in An. gambiae adults at the highest concentration, with no physical or chemical alteration of microplastics detected post-digestion.

2024 ORBi UMONS
Article Tier 2

Intake of polyamide microplastics affects the behavior and metabolism of Drosophila

Researchers found that exposure to polyamide microplastics altered feeding behaviour, reduced triglyceride and protein levels, and disrupted metabolism in Drosophila, with effects differing between sexes and increasing in severity at higher microplastic concentrations.

2022 Chemosphere 24 citations
Article Tier 2

Reproductive toxicity of polystyrene nanoplastics in Drosophila melanogaster under multi-generational exposure

Researchers exposed fruit flies to polystyrene nanoplastics across five consecutive generations and found increasing reproductive harm over time, including reduced egg laying and offspring survival. The damage worsened with each generation even at the same exposure levels, suggesting cumulative effects. The study indicates that nanoplastic exposure may pose growing reproductive risks across generations of organisms.

2023 Chemosphere 43 citations
Article Tier 2

Examining effects of ontogenic microplastic transference on Culex mosquito mortality and adult weight

Culex mosquito larvae were exposed to polystyrene microplastics at different sizes (2 μm and 15 μm) and concentrations, with MP ingestion confirmed and ontogenic transference of particles from aquatic larvae to terrestrial adults demonstrated, though no significant effects on adult mortality or weight were found. The study provides the first evidence of microplastic transfer across the aquatic-to-terrestrial life stage boundary in a common insect vector.

2018 The Science of The Total Environment 108 citations
Article Tier 2

Hazard assessment of ingested polystyrene nanoplastics in Drosophila larvae

Researchers assessed the hazard of ingested polystyrene nanoplastics in Drosophila larvae, examining effects on gut morphology, oxidative stress, and development to characterize toxicological risks of nanoplastic exposure in a model invertebrate organism.

2022 Environmental Science Nano 39 citations
Article Tier 2

Biochemical and physiological effects of multigenerational exposure to spheric polystyrene microplastics in Caenorhabditis elegans

Researchers found that multigenerational exposure of C. elegans to polystyrene microplastics at low concentrations triggered oxidative stress, increased detoxification enzyme activity, and caused accumulating physiological effects across five consecutive generations.

2023 Environmental Science and Pollution Research 10 citations
Article Tier 2

A fit-for-purpose categorization scheme for microplastic morphologies

Researchers studied the long-term effects of polypropylene microplastic exposure on the life history traits of the water flea Daphnia magna across three generations, finding progressively increasing reproductive impairment and reduced survival in successive generations. The multigenerational impacts exceeded those observed in single-generation tests.

2022 Integrated Environmental Assessment and Management 18 citations
Article Tier 2

Interactions of Ingested Polystyrene Microplastics with Heavy Metals (Cadmium or Silver) as Environmental Pollutants: A Comprehensive In Vivo Study Using Drosophila melanogaster

Researchers used Drosophila larvae to study polystyrene microplastic interactions with cadmium and silver, visualizing plastic passage through the intestinal barrier into hemolymph and finding that co-exposure to metals and microplastics produced synergistic toxic effects.

2022 Biology 35 citations
Article Tier 2

High-concentration polyethylene and polystyrene microplastics co-exposure shorten insect lifespan and impose ecological risk: Multi-omics evidence from Drosophila melanogaster

Researchers used fruit flies as a model organism to study how co-exposure to high concentrations of polyethylene and polystyrene microplastics affects insect lifespan. Multi-omics analysis revealed that microplastic co-exposure significantly shortened lifespan and disrupted key biological pathways, suggesting potential ecological risks from cumulative microplastic exposure in the environment.

2026 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology
Article Tier 2

Neuromuscular, retinal, and reproductive impact of low-dose polystyrene microplastics on Drosophila

Researchers found that even low doses of polystyrene microplastics impaired neuromuscular signaling, altered retinal function, and reduced reproductive rates in fruit flies, with gene expression changes in key signaling pathways underlying these effects.

2021 Environmental Pollution 25 citations
Article Tier 2

Polystyrene microplastics alter physiological parameters in the Drosophila model

Researchers investigated the effects of polystyrene micro- and nanoplastics on fruit flies (Drosophila melanogaster) and found dose- and size-dependent toxicity at both larval and adult stages. Exposure caused significant behavioral impairments, elevated markers of cellular stress, and activated key stress response genes, indicating that polystyrene microplastics induce oxidative stress and cellular damage.

2026 Environmental Science and Pollution Research
Article Tier 2

The multigenerational effects of nanoplastic exposure on fitness and oxidative stress of Drosophila melanogaster

Researchers assessed the multigenerational effects of nanoplastic exposure on the fitness and oxidative stress levels of a small aquatic crustacean across several generations. Negative effects on reproduction and oxidative balance accumulated across generations, suggesting that multigenerational exposure amplifies the harm from nanoplastics.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Multigenerational effects of nanoplastics on life-history traits and physiological responses in Drosophila melanogaster

Researchers conducted a multigenerational study exposing soil springtails (Folsomia candida) to polystyrene nanoplastics across two generations and assessed effects on life-history traits and physiology. Chronic multigenerational NP exposure reduced reproduction and survival, with effects persisting and sometimes intensifying in the second generation.

2025 NanoImpact
Article Tier 2

Immunological and Genotoxic Effects of Polystyrene Microparticles on the Model Insect Tenebrio molitor L. (Coleoptera: Tenebrionidae)

Researchers fed mealworm (Tenebrio molitor) larvae polystyrene microplastics at four dose levels and assessed immune function and DNA damage. Dietary exposure caused dose-dependent increases in larval mortality, immune cell changes, and genotoxic damage, indicating that even insect species used in waste degradation studies are harmed by microplastic ingestion.

2025 Transactions of the American Entomological Society