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61,005 resultsShowing papers similar to Enhanced binding of triclocarban to catalase induced by coexisting nanoplastics
ClearProbing the molecular mechanism of interaction between polystyrene nanoplastics and catalase by multispectroscopic techniques
Researchers investigated the molecular mechanism of interaction between polystyrene nanoplastics and the antioxidant enzyme catalase using multispectroscopic techniques, revealing how nanoplastic accumulation may disrupt enzymatic function and contribute to oxidative stress.
Spectroscopic investigations on the interaction between nano plastic and catalase on molecular level
Researchers investigated how polystyrene nanoplastics interact with the enzyme catalase at different pH levels, finding that nanoplastics alter the protein's secondary structure and reduce its enzymatic activity through static quenching and hydrophobic binding mechanisms.
Co-Existing Nanoplastics Further Exacerbates the Effects of Triclosan on the Physiological Functions of Human Serum Albumin
Scientists found that when nanoplastics and triclosan (an antimicrobial chemical) are present together, the nanoplastics make triclosan bind more strongly to human serum albumin, a key blood protein. This stronger binding disrupts the protein's normal enzyme function more than triclosan alone would. The findings are concerning because people are exposed to both nanoplastics and triclosan simultaneously, and their combined effect on blood proteins could be worse than either substance individually.
Adsorption behavior of triclosan on polystyrene nanoplastics: The roles of particle size, surface functionalization, and environmental factors
Researchers examined how triclosan, an antimicrobial compound common in personal care products, adsorbs onto polystyrene nanoplastics of different sizes and surface chemistries, finding that smaller particles and functionalized surfaces (with carboxyl or amine groups) bind more triclosan, with pH and salinity further modulating uptake — suggesting nanoplastics can serve as mobile carriers for this contaminant.
Interactions of microplastics and organic compounds in aquatic environments: A case study of augmented joint toxicity
Researchers investigated how polystyrene microplastics interact with the antimicrobial compound triclosan in simulated environmental and cellular conditions. They found that surface-functionalized microplastics adsorbed significantly more triclosan and released it under cellular conditions, with the combination producing greater toxicity to human intestinal cells than either contaminant alone. The study suggests that microplastics can amplify the harmful effects of co-occurring organic pollutants.
Nanoplastics composite norfloxacin induced changes in conformation and function of lysozyme and differential effects of co-exposure contamination
Researchers used spectroscopy and molecular docking to show that nanoplastics and the antibiotic norfloxacin form stable co-aggregates that bind near the active site of lysozyme, reducing its enzymatic activity by nearly 40% and altering the protein's secondary structure more severely than either contaminant alone.
Effects of particle size and solution chemistry on Triclosan sorption on polystyrene microplastic
Researchers characterized how the antimicrobial compound triclosan adsorbs onto polystyrene microplastics, finding that sorption is driven primarily by hydrophobic interactions and is highest at acidic pH, while temperature, ionic strength, and co-occurring heavy metals had little effect — suggesting polystyrene acts as an environmental carrier for triclosan.
Characterizing the binding interactions between virgin/aged microplastics and catalase in vitro
Researchers compared how virgin and UV-aged PVC microplastics interact with the antioxidant enzyme catalase in laboratory conditions. The study found that aged microplastics had more binding sites and caused greater structural changes to the enzyme, including loosening of protein chains, though neither form affected the enzyme's core activity since the particles were too large to enter the enzyme's interior.
Does triclosan adsorption on polystyrene nanoplastics modify the toxicity of single contaminants?
Researchers investigated whether triclosan adsorption onto polystyrene nanoplastics modifies the toxicity of each contaminant individually, using a multi-tiered approach to assess how nanoplastic carrier effects alter the combined hazard of this common antimicrobial agent in aquatic environments.
The Formation of Protein Corona by Nanoplastics and Horseradish Peroxidase
Researchers investigated the formation of protein corona on amino-functionalized polystyrene nanoplastics by horseradish peroxidase, characterizing the adsorption interaction using multiple analytical approaches to understand how nanoplastics acquire protein coatings in biological environments. They found that nanoplastics readily adsorb the enzyme to form a stable protein corona, which may alter both nanoplastic behavior in biological systems and enzyme activity.
Evidence of microplastics release from polythene and paper cups exposed to hot and cold: A case study on the compromised kinetics of catalase
Researchers found that both polythene bags and paper cups release microplastic particles when exposed to hot and cold water at various time intervals. The study demonstrated that these released microplastics can bind to and alter the structure of the antioxidant enzyme catalase, reducing its enzymatic activity by approximately 1.4-fold, suggesting that everyday plastic-containing materials may release particles that interfere with biological processes.
Study on the binding of polystyrene microplastics with superoxide dismutase at the molecular level by multi-spectroscopy methods
Researchers used multiple spectroscopy methods to study how polystyrene microplastics interact with the antioxidant enzyme superoxide dismutase (SOD) at the molecular level. The study found that microplastics altered SOD's protein structure, forming larger complexes and increasing the enzyme's activity in a concentration-dependent manner, providing insights into how microplastics may affect biological antioxidant systems.
Insights into the interaction mechanism of ofloxacin and functionalized nano-polystyrene.
This study investigated how the antibiotic ofloxacin interacts with functionalized polystyrene nanoplastics, finding that surface charge and functional groups on the nanoplastics strongly influenced binding strength and mechanisms. The results improve understanding of how nanoplastics can act as carriers for antibiotics in the environment, potentially altering their fate and biological effects.
Interactionsbetween Nanoplastics and Antibiotics:Implications for Nanoplastics Aggregation in Aquatic Environments
Researchers studied how the antibiotics ciprofloxacin and tetracycline interact with polystyrene nanoplastics in aquatic environments, finding that these drugs alter nanoplastic surface properties and aggregation behavior under environmentally relevant conditions.
Adsorption of clarithromycin on polystyrene nanoplastics surface and its combined adverse effect on serum albumin
Researchers examined how the antibiotic clarithromycin binds to the surface of polystyrene nanoplastics and how this combination interacts with blood proteins. They found that the drug readily adsorbed onto the nanoplastic surface and that the drug-nanoplastic complex altered the structure and function of serum albumin more than either substance alone. The findings suggest that nanoplastics could amplify the biological effects of pharmaceutical pollutants by acting as carriers in the body.
Size-dependent effects of nanoplastics on structure and function of superoxide dismutase
Researchers used multi-spectroscopic techniques to examine how nanoplastics of different sizes interact with and alter the structure and function of the antioxidant enzyme superoxide dismutase. The study found size-dependent effects, with nanoplastics binding to the enzyme and altering its secondary structure, ultimately reducing its activity, which has implications for understanding how nanoplastics may disrupt cellular antioxidant defenses.
Nanoplastics alter the conformation and activity of human serum albumin
Researchers investigated how polystyrene nanoplastics interact with human serum albumin, a key blood protein, and found that nanoplastics bind to the protein through hydrophobic forces, altering its structure and reducing its enzymatic activity. The study suggests that nanoplastic exposure could interfere with normal protein function in the bloodstream, highlighting the need for regulation of nanoplastics in consumer products.
Time evolution of protein corona formed by polystyrene nanoplastics and urease
Researchers investigated how polystyrene nanoplastics interact with urease to form a protein corona over time, finding that the corona's composition and structure evolve dynamically, potentially altering the environmental fate and hazards of nanoplastics.
Possible Molecular Mechanisms Underlying the Decrease in the Antibacterial Activity of Protamine-like Proteins after Exposure of Mytilus galloprovincialis to Chromium and Mercury
Researchers investigated why protamine-like proteins lose antibacterial activity after exposure to polystyrene nanoparticles, identifying molecular mechanisms including conformational changes and protein-nanoparticle binding that reduce antimicrobial effectiveness.
Insights into the synergistic toxicity mechanisms caused by nano- and microplastics with triclosan using a dose-dependent functional genomics approach in Saccharomyces cerevisiae
Researchers used yeast functional genomics to investigate the combined toxicity of polystyrene nano- and microplastics with the antimicrobial compound triclosan. They found that the combined exposure produced synergistic toxic effects that were more harmful than either contaminant alone, disrupting cellular processes related to membrane integrity and protein function. The study provides molecular-level evidence that microplastics may amplify the toxicity of co-occurring chemical pollutants.
Binding of Tetrabromobisphenol A and S to Human Serum Albumin Is Weakened by Coexisting Nanoplastics and Environmental Kosmotropes
Researchers studied how polystyrene nanoplastics interact with human serum albumin and brominated flame retardants (TBBPA and TBBPS) under various conditions. The study found that while the protein helped disperse nanoplastics alone, adding flame retardants promoted aggregate formation, with environmental salt conditions further influencing these interactions. These findings suggest that the behavior of nanoplastics and co-occurring pollutants in both biological and natural water systems may be more complex than previously understood.
The sorption behavior of triclosan on microplastics: aging effects and mechanisms
Researchers investigated how environmental aging processes change the ability of polyethylene, polypropylene, and polystyrene microplastics to absorb the antimicrobial compound triclosan. They found that aging increased sorption capacity for polyethylene but decreased it for polypropylene, with polystyrene showing mixed results depending on the aging method. The changes were driven by modifications to surface chemistry, particularly the introduction of oxygen-containing functional groups that alter hydrophobic and electrostatic interactions.
Protein corona as a mediator in antibiotic adsorption onto microplastics: Mechanisms and implications
Researchers investigated how protein coronas that form on microplastic surfaces mediate the adsorption of antibiotics in environmental settings. The study provides direct evidence that biological molecules on microplastics facilitate chemical interactions with antibiotics, creating complexes that may pose risks to human health through environmental exposure pathways.
Effects of biofilm formation on triclosan adsorption by UV-aged and pristine polystyrene microplastics in aquatic environments
Researchers investigated how biofilm formation on UV-aged versus pristine polystyrene microplastics affected triclosan adsorption, finding that biofilm-colonized aged microplastics had altered surface properties that changed triclosan uptake compared to unaged particles.