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Papers
4 resultsShowing papers from National Research Centre for the Working Environment
ClearNext Generation Risk Assessment approaches for advanced nanomaterials: Current status and future perspectives
This paper proposes a framework for assessing the safety of advanced nanomaterials using newer testing methods that reduce the need for animal studies. The tiered approach combines existing data with targeted testing to evaluate health risks cost-effectively. While focused on engineered nanomaterials broadly, the framework is relevant to understanding the risks of nanoplastics and could help regulators develop safety standards for these emerging contaminants.
A template wizard for the cocreation of machine-readable data-reporting to harmonize the evaluation of (nano)materials
Researchers created a user-friendly tool called the Template Wizard that helps scientists record and share their nanomaterial safety data in standardized, machine-readable formats. The tool includes over 60 templates for common experiments in nanosafety research, including toxicity testing. While focused on data management rather than microplastics directly, standardized reporting of nanoplastic safety data is critical for building a reliable evidence base on the health risks of micro- and nanoplastics.
Tyre wear nanoparticles as test for a nano risk governance framework
A nano risk governance framework developed collaboratively by three EU Horizon 2020 consortia was applied to tire wear nanoparticles as a real-world test case, evaluating its practicality for manufacturers, regulators, and other stakeholders. The exercise identified strengths and gaps in the framework and produced recommendations for governing emerging nanomaterial risks.
122 Elucidating the Impact of Inhaled Micro-, Nanoplastics (MNPs) from Surgical Face Masks In Vitro
This in vitro study tested whether polypropylene particles shed from surgical face masks can harm human lung cells, finding that aerosolized mask-derived microplastics caused dose-dependent cell death, increased inflammatory markers (IL-1β, IL-6, IL-8), and early signs of DNA damage. The results suggest that breathing particles released from plastic masks represents a real hazard to the respiratory system, though more research is needed to establish real-world exposure levels.