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Papers
5 resultsShowing papers from Henan Cancer Hospital
ClearDiscovery and analysis of microplastics in human bone marrow
For the first time, researchers detected microplastics in human bone marrow, finding plastic particles in all 16 samples tested. The most common types were polyethylene and polystyrene, with about 90% of particles smaller than 100 micrometers. This discovery shows that microplastics can penetrate deep into the body and reach the tissue where blood cells are made, raising questions about potential effects on blood cell production and immune function.
The impact of gut microbial signals on hematopoietic stem cells and the bone marrow microenvironment
This review explores how gut bacteria influence the production and development of blood cells in the bone marrow by sending chemical signals through microbial byproducts. While not directly about microplastics, the research is highly relevant because microplastics are known to disrupt gut bacteria communities. If microplastics alter the gut microbiome, they could indirectly affect blood cell production and immune function through this gut-bone marrow connection.
Polystyrene nanoplastics induce haematotoxicity with cell oxeiptosis and senescence involved in C57BL / 6J mice
Researchers exposed mice to polystyrene nanoplastics over 42 days and found that the particles accumulated in bone tissue and caused significant damage to blood-forming cells. The nanoplastics triggered oxidative stress and activated cell death and aging pathways in bone marrow. The study suggests that nanoplastic exposure may pose risks to the blood-forming system by disrupting the normal production of blood cells.
Metabolomic characteristics in human CD34+ hematopoietic stem/progenitor cells exposed to polystyrene nanoplastics
Researchers examined metabolomic changes in human CD34+ hematopoietic stem/progenitor cells exposed to polystyrene nanoplastics, finding significant metabolic disruptions that suggest nanoplastics may impair human blood cell development.
Tire wear particles: An emerging threat to soil health
This review synthesizes knowledge about tire wear particles — a major but often overlooked source of microplastic-like pollutants — in soil ecosystems. Tire wear particles contain toxic metals and organic compounds that harm soil microbes, invertebrates, and plants, but most research to date has focused on aquatic systems rather than soils.