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Papers
8 resultsShowing papers from Fifth Affiliated Hospital of Sun Yat-sen University
ClearMicroplastics in the Lung Tissues Associated with Blood Test Index
Researchers analyzed lung tissue from 12 nonsmoking patients and found microplastics in all samples, with 12 different plastic types detected and polypropylene being the most common. Women and people living near major roads had higher microplastic levels in their lungs, and the amounts correlated with changes in blood clotting markers. This study provides direct evidence that microplastics accumulate in human lungs and may affect blood health, even in people who have never smoked.
Evidence of Microplastics in Bronchoalveolar Lavage Fluid among Never-Smokers: A Prospective Case Series
Researchers conducted a prospective case series examining bronchoalveolar lavage fluid from 18 never-smokers in China using laser direct infrared spectroscopy and scanning electron microscopy. The study found evidence of microplastic deposition in the respiratory tract, suggesting that inhaled microplastics can accumulate in the lungs even among people who have never smoked.
Nanoplastics in the Human Respiratory System
This research paper reports on the detection and characterization of nanoplastics in the human respiratory system, published in a leading pulmonary medicine journal. The study adds to growing evidence that extremely small plastic particles are present in human lungs. The findings underscore the importance of understanding inhalation as a key route of human exposure to plastic pollution.
New Evidence of Microplastics in the Lower Respiratory Tract: Inhalation through Smoking
Researchers collected lung fluid samples from smokers and nonsmokers and found that smokers had significantly higher concentrations of microplastics in their lower respiratory tract. A laboratory smoking simulation confirmed that cigarette smoke itself carries microplastic particles, including polyurethane and silicone. The study identifies smoking as a previously unrecognized route of microplastic inhalation, adding to the known health concerns associated with tobacco use.
Association between exposure to microplastics and lipid disorders: A case-control study
Researchers conducted a case-control study examining the association between internal microplastic exposure and lipid metabolism disorders. The study found that microplastic exposure was significantly associated with lipid disorders, providing novel evidence that microplastics may adversely affect lipid metabolism in humans.
Microplastics drives ILC2s function and fatty acid metabolism in allergic airway inflammation via PPARγ signaling
Researchers found that microplastics exacerbate allergic airway inflammation in house dust mite-sensitized mice by promoting epithelial barrier disruption and type 2 immune activation. The study revealed that microplastics drive the function of innate lymphoid cells (ILC2s) and alter fatty acid metabolism through the PPARgamma signaling pathway, providing mechanistic insight into how airborne microplastics may worsen respiratory allergies.
Neonatal Hypoglycemia Related to Glycine Levels in Uncontrolled Gestational Diabetes Mellitus during Mid-Late Pregnancy: Multicenter, Prospective Case-Cohort Observational Study
This study explored the relationship between gestational diabetes mellitus (GDM) and neonatal cord blood amino acid and carnitine levels in mothers with glycosylated hemoglobin of 5.5-6.4% during mid-late gestation. Among 7,289 participants, GDM was associated with altered neonatal metabolic profiles, including changes linked to neonatal hypoglycemia risk.
Analysis of microplastics released from plastic take-out food containers based on thermal properties and morphology study
This study measured microplastics released from three types of plastic take-out food containers — polypropylene, polyethylene, and expanded polystyrene — when filled with hot water. Expanded polystyrene released the most particles by far (up to 2.8 million per liter), and over 96% of particles from all containers were smaller than 10 micrometers, small enough to be absorbed into the gut.