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Polystyrene nanoplastics induce oxidative stress in Aurelia coerulea polyps, microglia, and mice

Frontiers in Immunology 2025 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Mingshuai Song, Zhenyu Wei, Jingqiang Wang, Liangzhi Li, Xiangyu Li, Xingjie Ma, Marina Pozzolini, Xinyan Liu, Xiao Liang, Ping Zhong

Summary

Researchers tested the effects of polystyrene nanoplastics across three very different biological systems: jellyfish polyps, brain immune cells, and mice. Despite the different organisms, all three showed consistent oxidative stress responses when exposed to the nanoplastics. The converging evidence across marine, cellular, and mammalian models highlights the widespread biological risks these tiny plastic particles may pose.

Polymers
Models

While these models represent distinct organisms and biological contexts, all demonstrated consistent oxidative stress responses upon PS-NPs exposure. Although we do not claim direct equivalency across species, the converging evidence from marine, cellular, and mammalian systems highlights the widespread biological risks posed by nanoplastics. These findings provide a foundation for evaluating environmental and public health threats associated with PS-NPs.

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