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Nanoplastics as a potential environmental health factor: effects of polystyrene nanoparticles on human intestinal epithelial Caco-2 cells

Environmental Science Nano 2019 203 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Constanza Cortés, Josefa Domenech, Marcela Salazar, Susana Pastor, Ricard Marcos, Alba Hernández

Summary

Researchers tested how polystyrene nanoparticles interact with human intestinal cells in the lab. They found that the nanoparticles were readily taken up by the cells in a concentration-dependent manner, but no significant toxic effects were observed under the conditions tested. The study suggests that while nanoplastics can enter gut cells, their short-term toxicity at the tested levels appears limited.

Polymers

Our results show that both nPS are easily internalized by Caco-2 cells in a concentration-dependent manner, but no relevant toxic effects are observed under the analyzed exposure conditions.

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