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Uptake, accumulation and associated cellular alterations of environmental samples of microplastics in the seaworm Hediste diversicolor

Journal of Hazardous Materials 2020 66 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Nesrine Zitouni, Nesrine Zitouni, Giuseppe De Marco, Omayma Missawi, Omayma Missawi, Giuseppe De Marco, Iteb Boughattas, Giuseppe De Marco, Omayma Missawi, Nesrine Zitouni, Tiziana Cappello, Nesrine Zitouni, Iteb Boughattas, Iteb Boughattas, Nesrine Zitouni, Giuseppe De Marco, Omayma Missawi, Omayma Missawi, Giuseppe De Marco, Iteb Boughattas, Omayma Missawi, Nesrine Zitouni, Giuseppe De Marco, Tiziana Cappello, Nesrine Zitouni, Tiziana Cappello, Tiziana Cappello, Nesrine Zitouni, Maria Maisano, Giuseppe De Marco, Omayma Missawi, Noureddine Bousserrhıne, Noureddine Bousserrhıne, Noureddine Bousserrhıne, Noureddine Bousserrhıne, Iteb Boughattas, Nesrine Zitouni, Giuseppe De Marco, Nesrine Zitouni, Iteb Boughattas, Noureddine Bousserrhıne, Noureddine Bousserrhıne, Noureddine Bousserrhıne, Noureddine Bousserrhıne, Mohamed Bannı Tiziana Cappello, Omayma Missawi, Tiziana Cappello, Nesrine Zitouni, Iteb Boughattas, Nesrine Zitouni, Giuseppe De Marco, Nesrine Zitouni, Tiziana Cappello, Sabrina Belbekhouche, Omayma Missawi, Mohamed Bannı Sabrina Belbekhouche, Omayma Missawi, Tiziana Cappello, Nesrine Zitouni, Tiziana Cappello, Mohamed Bannı Maria Maisano, Mohamed Bannı Omayma Missawi, Nesrine Zitouni, Giuseppe De Marco, Maria Maisano, Mohamed Bannı Maria Maisano, Maria Maisano, Nesrine Zitouni, Nesrine Zitouni, Nesrine Zitouni, Maria Maisano, Tiziana Cappello, Tiziana Cappello, Tiziana Cappello, Tiziana Cappello, Tiziana Cappello, Iteb Boughattas, Iteb Boughattas, Iteb Boughattas, Omayma Missawi, Nesrine Zitouni, Nesrine Zitouni, Mohamed Guerrouache, Tiziana Cappello, Maria Maisano, Vanessa Alphonse, Vanessa Alphonse, Nesrine Zitouni, Nesrine Zitouni, Giuseppe De Marco, Iteb Boughattas, Vanessa Alphonse, Iteb Boughattas, Vanessa Alphonse, Omayma Missawi, Omayma Missawi, Mohamed Guerrouache, Giuseppe De Marco, Giuseppe De Marco, Tiziana Cappello, Maria Maisano, Tiziana Cappello, Mohamed Bannı Mohamed Bannı Maria Maisano, Giuseppe De Marco, Maria Maisano, Maria Maisano, Nesrine Zitouni, Maria Maisano, Noureddine Bousserrhıne, Tiziana Cappello, Maria Maisano, Iteb Boughattas, Noureddine Bousserrhıne, Sabrina Belbekhouche, Tiziana Cappello, Iteb Boughattas, Omayma Missawi, Mohamed Guerrouache, Mohamed Guerrouache, Tiziana Cappello, Mohamed Bannı Iteb Boughattas, Maria Maisano, Nesrine Zitouni, Iteb Boughattas, Vanessa Alphonse, Mohamed Bannı Mohamed Bannı Maria Maisano, Mohamed Bannı Mohamed Bannı Mohamed Bannı Maria Maisano, Mohamed Bannı Mohamed Bannı Tiziana Cappello, Tiziana Cappello, Tiziana Cappello, Tiziana Cappello, Omayma Missawi, Omayma Missawi, Noureddine Bousserrhıne, Sabrina Belbekhouche, Vanessa Alphonse, Noureddine Bousserrhıne, Tiziana Cappello, Vanessa Alphonse, Vanessa Alphonse, Noureddine Bousserrhıne, Mohamed Bannı Sabrina Belbekhouche, Mohamed Bannı Sabrina Belbekhouche, Mohamed Bannı Vanessa Alphonse, Vanessa Alphonse, Noureddine Bousserrhıne, Mohamed Bannı Mohamed Bannı Tiziana Cappello, Mohamed Guerrouache, Mohamed Bannı Omayma Missawi, Mohamed Guerrouache, Mohamed Bannı Maria Maisano, Mohamed Bannı Mohamed Bannı Maria Maisano, Mohamed Bannı Mohamed Bannı Mohamed Bannı Mohamed Bannı Noureddine Bousserrhıne, Mohamed Bannı Mohamed Bannı Maria Maisano, Mohamed Bannı Mohamed Bannı Mohamed Bannı Mohamed Bannı Mohamed Bannı Mohamed Bannı Noureddine Bousserrhıne, Omayma Missawi, Tiziana Cappello, Vanessa Alphonse, Vanessa Alphonse, Mohamed Bannı Mohamed Bannı Mohamed Bannı Noureddine Bousserrhıne, Mohamed Bannı Noureddine Bousserrhıne, Mohamed Bannı Mohamed Bannı Maria Maisano, Mohamed Bannı Maria Maisano, Mohamed Bannı Tiziana Cappello, Omayma Missawi, Mohamed Bannı

Summary

Hediste diversicolor seaworms exposed to environmental microplastic mixtures collected from Tunisian beaches accumulated PE, PP, LDPE, and HDPE particles in their tissues and showed cellular damage including lipid peroxidation and lysosomal membrane destabilization at environmentally relevant concentrations.

The ubiquitous distribution of microplastics (MPs) in the marine environment raises global concern to understand their impact. Environmental MPs have been shown to exhibit different physicochemical properties during their life cycles. However, the body of knowledge regarding their accumulation and biological effects is still significantly limited compared to manufactured MPs. To evaluate the hazardous effects of a mixture of environmental MPs collected along the Tunisian beaches, their accumulation and cellular effects were investigated in Hediste diversicolor. MP sample was composed of polyethylene (PE), polyethylene vinyl acetate (PEVA), low-density polyethylene (LDPE), high-density polyethylene (HDPE), polypropylene (PP) and polyamide (PA) analyzed using Raman microspectroscopy (RM). The concentrations of MPs in seaworm tissues increased over time, following the order 1.2-0.45 µm > 3-1.2 µm > 100-3 µm. The ingestion of MPs by H. diversicolor reduced their survival and growth, affected the neuro-transmission and antioxidant pathways. Our data emphasised that the toxic effects of environmental MPs were closely related to the exposure dose and period. The results also demonstrated that the size distribution of MPs in seaworms was mainly correlated with biochemical markers. This study highlights the ecological risk in the ingestion and accumulation of environmental MPs by biota that threatens their functional parameters.

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