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Additional file 2 of Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis
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This is a supplementary data file providing numerical values for a study on how polystyrene micro- and nanoplastics damage the intestinal barrier through oxidative stress-induced cell death. The underlying study is relevant to understanding how plastic particles ingested through food or water may harm the human gut lining.
Additional file 2. These values correspond to the heatmaps in Fig. 5.
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This mouse study found that when micro-sized and nano-sized polystyrene particles were present together, as they would be in the real world, they caused more intestinal damage than either size alone. The combined exposure increased gut permeability by killing intestinal lining cells through oxidative stress, weakening the barrier that keeps harmful substances out of the bloodstream. This is important because real-world microplastic exposure always involves a mix of particle sizes, meaning health risks may be greater than single-size lab studies suggest.
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