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Exposure to Polystyrene Nanoplastics Induces an Anxiolytic-Like Effect, Changes in Antipredator Defensive Response, and DNA Damage in Swiss Mice
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Exposure to polystyrene nanoplastics induces an anxiolytic-like effect, changes in antipredator defensive response, and DNA damage in Swiss mice
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Researchers exposed male Swiss mice to polystyrene nanoplastics at two doses over 20 days and assessed behavioral, neurological, and genetic effects. The study found that nanoplastic exposure induced anxiolytic-like behavior, altered antipredator defensive responses, and caused DNA damage in erythrocytes, suggesting that nanoplastics can affect mammalian brain function and genomic integrity.
Stress (Cortisol) and Hepatotoxic Effects of Polystyrene Micro- and Nanoplastics in Swiss Albino Mice: A Comparative Study
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Researchers exposed Swiss albino mice to polystyrene micro- and nanoplastics and compared the stress and liver toxicity responses, finding that both sizes elevated cortisol levels and caused hepatotoxic damage, with nanoplastics generally producing more pronounced physiological disruption than microplastics.
Prenatal exposure to polystyrene nanoplastics caused testicular development toxicities and relative mechanisms in male offspring mice from embryo to adulthood
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Scientists exposed pregnant mice to nanoplastics (tiny plastic particles found in our environment, blood, and even placentas) and found their male offspring had slowed growth before birth, hit puberty earlier, and had reduced fertility as adults. The nanoplastics appeared to disrupt key genes and cells needed for normal testicle development and hormone production. While this is animal research, it adds to growing evidence that plastic exposure during pregnancy could affect a baby's reproductive development later in life.
Biochemical, Histological and Molecular Docking into the Impact of Polystyrene Nanoplastics on Antioxidant Enzymes and Testicular Health in Rats
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Tiny plastic particles called nanoplastics, found widely in our environment, may harm male fertility, according to a new rat study. Rats exposed to higher doses of these plastics showed weakened antioxidant defenses and physical damage to testicular tissue, including fewer developing sperm cells. While this research was done in rats, not humans, it adds to growing concerns that the microplastics and nanoplastics we're routinely exposed to through food, water, and air could pose risks to reproductive health.
Cellular and Animal Toxicities of Micro- and Nanoplastics
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Researchers reviewed evidence from cell and animal studies on the toxic effects of micro- and nanoplastics, finding that these particles can cause inflammation, oxidative stress, and organ damage in laboratory models, raising concern about what chronic low-level human exposure might mean for long-term health.
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