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P07-43 Subchronic exposure to polystyrene microplastic provokes intestinal damage in gilthead seabreams (Sparus aurata)

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Polymers

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Impact of polystyrene microplastic exposure on gilthead seabream (Sparus aurata Linnaeus, 1758): Differential inflammatory and immune response between anterior and posterior intestine

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Researchers fed gilthead seabream polystyrene microplastics for 21 days and found they triggered inflammation and immune disruption in both sections of the intestine, with the rear portion more severely affected. The microplastics activated inflammatory signaling pathways and weakened the gut barrier by reducing tight junction proteins. The findings suggest microplastic ingestion could compromise gut health and immune function in fish.

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