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Tanshinone IIA May Inhibit Gastric Cancer via Affecting the Intestinal Microbiome
Summary
Researchers investigated whether tanshinone IIA, a compound derived from Salvia miltiorrhiza, inhibits gastric cancer tumor growth through modulation of the intestinal microbiome and regulation of NF-kB signaling. The study found that tanshinone IIA altered the gut microbial composition and suppressed NF-kB pathway activity, suggesting a microbiome-mediated mechanism underlying its anti-tumor effects.
Tanshinone IIA may inhibit GC tumor growth via affecting the intestinal microbiome through regulating the NF-κB signaling.
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