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Human Health Effects
Nanoplastics
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Neurotoxic effects of different sizes of plastics (nano, micro, and macro) on juvenile common carp (Cyprinus carpio)
Frontiers in Molecular Neuroscience2022
53 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 55
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Christopher J. Martyniuk,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Mohamed Hamed,
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Mohamed Hamed,
Christopher J. Martyniuk,
Christopher J. Martyniuk,
Christopher J. Martyniuk,
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Mohamed Hamed,
Mohamed Hamed,
Christopher J. Martyniuk,
Mervat Naguib,
Mervat Naguib,
Mervat Naguib,
Jae‐Seong Lee,
Christopher J. Martyniuk,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Christopher J. Martyniuk,
Christopher J. Martyniuk,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Christopher J. Martyniuk,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Mohamed Hamed,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Christopher J. Martyniuk,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Christopher J. Martyniuk,
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Jae‐Seong Lee,
Christopher J. Martyniuk,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Christopher J. Martyniuk,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Jae‐Seong Lee,
Alaa El‐Din H. Sayed
Summary
Researchers assessed the neurotoxic effects of polyethylene plastics at nano, micro, and macro sizes on juvenile common carp brains. The study found that all plastic sizes reduced brain enzyme activity by 30-40%, with smaller particles causing more pronounced effects, and histological examination revealed structural changes in brain tissue, suggesting that size plays a significant role in plastic neurotoxicity.
Using common carp as a model, we assessed the effects of polyethylene (PE) plastics on the brain. We measured activity of acetylcholinesterase (AChE), monoamine oxidase (MAO), and the content of nitric oxide (NO) in carp brain following exposure to 100 mg/L of either macroplastics (MaP), microplastics (MPs), or nanoplastic (NPs) for 15 days compared to an unexposed group. Following exposure, each biochemical biomarker was reduced 30-40%, with a higher magnitude of change corresponding to the smaller size of the particles (NPs > MPs > MaPs). In the carp tectum, exposure for 15 days to plastic particles caused varying degrees of necrosis, fibrosis, changes in blood capillaries, tissue detachment, edema, degenerated connective tissues, and necrosis in large cerebellar neurons and ganglion cells. In the carp retina, there was evidence for necrosis, degeneration, vacuolation, and curvature in the inner layer. Here we provide evidence that exposure to plastic particles can be associated with neurotoxicity in common carp.