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Composition of the gut microbiota at the phylum level following the administration of MP.
Summary
Researchers characterized gut microbiota composition at the phylum level in wild-type and leptin-knockout obese mice following microplastic administration, finding statistically significant shifts in phylum-level bacterial distribution that differed between obese and normal mice.
(a) Fecal microbiota distribution at the phylum level in WT and Lep KO mice. (b) Relative level of fecal microbiota distribution at the phylum level in WT and Lep KO mice. Each color represents one bacterial phylum. (c) Heat map showing a significant difference. Different colors indicate the relative abundance of each phylum. The data are reported as mean ± SD values. *, p < 0.05 compared to the Vehicle-treated group. #, p < 0.05 compared to the WT mice. Abbreviation: WT; wild type, Lep KO; leptin knockout, MP; microplastics.
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