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Multi-biomarkers hazard assessment of microplastics with different polymers by acute embryo test and chronic larvae test with zebrafish (Danio rerio)

Aquatic Toxicology 2023 27 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Yuling Chen, Xiang‐Rong Xu, Xiang‐Rong Xu, Yuling Chen, Chenxi Wu Chenxi Wu Yuling Chen, Chenxi Wu Yuling Chen, Xiang‐Rong Xu, Chenxi Wu Xiang‐Rong Xu, Chenxi Wu Ming Duan, Xiang‐Rong Xu, Yuling Chen, Yuling Chen, Chenxi Wu Xiang‐Rong Xu, Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Yuling Chen, Yuling Chen, Chenxi Wu Chenxi Wu Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Yuling Chen, Ming Duan, Xiang‐Rong Xu, Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Ming Duan, Xiang‐Rong Xu, Xiang‐Rong Xu, Ming Duan, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu Xiang‐Rong Xu, Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Chenxi Wu Xiang‐Rong Xu, Ming Duan, Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu Chenxi Wu Xiang‐Rong Xu, Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu Chenxi Wu Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Xiang‐Rong Xu, Chenxi Wu

Summary

Researchers compared the toxicity of four common microplastic types to zebrafish using both short-term embryo and longer-term larval tests. While none of the microplastics affected embryo development at environmentally relevant concentrations, chronic exposure caused accelerated heartbeat rates and altered swimming behavior in larvae. The study highlights that different polymer types produce varying toxic effects and that longer-term exposure assessments may be more revealing than short-term tests.

Polymers

PE PET PP PS

Body Systems

Cardiovascular Nervous

Models

Zebrafish

Microplastics as emerging contaminants show various composition features in the environment. However, influence of polymer types on the toxicity of microplastics is still unclear, thus affecting evaluation of their toxicity and ecological risks. In this work, toxic effects of microplastics (fragment, 52-74 μm) with different polymer types including polyethylene (PE), polyethylene terephthalate (PET), polypropylene (PP) and polystyrene (PS) to zebrafish (Danio rerio) were studied using acute embryo test and chronic larvae test. Silicon dioxide (SiO) was used as a control representing natural particles. Results showed microplastics with different polymers had no influence on embryonic development at environmental relevant concentration (10 particles/L), but could lead to accelerated heartbeat rate and increased embryonic death when exposed to SiO, PE and PS at higher concentrations (10 and 10 particles/L). Chronic exposure for zebrafish larvae indicated different polymers of microplastics did not affect zebrafish larvae' feeding and growth, nor induce oxidative stress. But larvae' locomotion level and AChE (acetylcholinesterase) activities could be inhibited by SiO and microplastics at 10 particles/L. Our study demonstrated negligible toxicity of microplastics at environmental relevant concentration, while different polymers of microplastics have similar toxic effects as SiO at high concentrations. We suggest that microplastic particles may have the same biological toxicity as natural particles.

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