We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
In vitro bioassays for monitoring drinking water quality of tap water, domestic filtration and bottled water
Summary
Researchers used cell-based bioassays to assess the toxicity of tap water, bottled water, and home-filtered water and found that non-regulated disinfection byproducts — chemical compounds formed when water is treated — were the main drivers of oxidative stress responses. The study demonstrates that standard chemical testing alone misses important toxicological hazards in drinking water.
Bioassays are an important complement to chemical analysis of disinfection by-products (DBPs) in drinking water. Comparison of the measured oxidative stress response and mixture effects predicted from the detected chemicals and their relative effect potencies allowed the identification of the forcing agents for the mixture effects, which differed by location but were mainly non-regulated DBPs. This study demonstrates the relevance of non-regulated DBPs from a toxicological perspective. In vitro bioassays, in particular reporter gene assays for oxidative stress response that integrate different reactive toxicity pathways including genotoxicity, may therefore serve as sum parameters for drinking water quality assessment.
Sign in to start a discussion.
More Papers Like This
Tools for monitoring toxicological and genotoxicological changes in a drinking water treatment plant in Northeast Italy
Researchers used multiple bioassays including Daphnia, algae, and human leukocytes to monitor toxicological changes in a drinking water treatment plant in northeast Italy treating fluorinated compound-contaminated groundwater. While standard chemical parameters met regulatory limits, some biological tests detected residual toxicity after treatment, highlighting the value of bioassays for water safety assessment.
A Low-Cost Electrochemical Cell Sensor Based on MWCNT-COOH/α-Fe2O3 for Toxicity Detection of Drinking Water Disinfection Byproducts
A low-cost electrochemical sensor based on MWCNT-COOH/α-Fe2O3 was developed to detect toxicity of drinking water disinfection byproducts, offering a simpler and faster alternative to traditional bioassays for assessing health risks in treated water supplies.
Evaluation of Surface Water Quality with Biochemical Assays
Researchers evaluated two rapid, low-cost biochemical assays — a peroxidase toxicity test and a pyruvate-glyoxalate pathway assay — for assessing surface water quality near urban areas. Both assays effectively detected contamination in field samples, offering a faster alternative to conventional water quality monitoring.
A review on the detection of micro and nano plastics in drinking water
This review assessed detection methods for micro- and nanoplastics in drinking water, covering both tap and bottled water where these contaminants have been widely documented. The authors evaluated current analytical techniques and identified gaps in standardized monitoring approaches.
A review on the detection of micro and nano plastics in drinking water
This review covered detection methodologies for micro- and nanoplastics in drinking water, including both tap and bottled water sources. The authors synthesized current analytical approaches and highlighted the need for standardized methods across studies.