We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Retracted: Exogenous Hydrogen Sulfide Mitigates Oxidative Stress and Mitochondrial Damages Induced by Polystyrene Microplastics in Osteoblastic Cells of Mice
Summary
This entry retracts a previously published study on how hydrogen sulfide affected oxidative stress caused by polystyrene microplastics in mouse bone cells. The retraction means the original conclusions about microplastic effects on bone health cannot be relied upon until the errors are addressed.
[This retracts the article DOI: 10.1155/2023/2516472.].
Sign in to start a discussion.
More Papers Like This
Exogenous Hydrogen Sulfide Mitigates Oxidative Stress and Mitochondrial Damages Induced by Polystyrene Microplastics in Osteoblastic Cells of Mice
Researchers found that polystyrene microplastics induced oxidative stress, mitochondrial damage, and altered gene expression in mouse bone-forming cells, while exogenous hydrogen sulfide treatment mitigated these toxic effects by modulating key signaling pathways.
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells
Researchers investigated how polystyrene nanoplastics damage reproductive cells in mice and whether endogenous hydrogen sulfide can provide protection. The study found that nanoplastics induced mitochondrial damage, excessive autophagy, and cell death in spermatocyte-derived cells, while hydrogen sulfide counteracted these effects by regulating oxidative stress defense pathways.
Keap1-Nrf2 pathway up-regulation via hydrogen sulfide mitigates polystyrene microplastics induced-hepatotoxic effects
Researchers investigated whether hydrogen sulfide could protect against liver damage caused by polystyrene microplastics in mice. They found that hydrogen sulfide activated the Keap1-Nrf2 antioxidant defense pathway, which reduced oxidative stress and inflammation in liver tissues exposed to microplastics. The study suggests that the Keap1-Nrf2 pathway plays a protective role against microplastic-induced hepatotoxicity and that hydrogen sulfide could be a potential therapeutic agent.
Effects of Polystyrene Microplastics on Bone-related Protein Expression, Mineralization Capacity, and Mitochondrial Function in Osteoblast-like Cells (mg-63)
Osteoblast-like cells (MG-63) were exposed to polystyrene microplastics at 5–50 µg/mL, and bone-related protein expression, mineralisation capacity, and mitochondrial function were assessed. PS-MPs were internalised and reduced mineralisation and osteocalcin levels while impairing mitochondrial bioenergetics, suggesting microplastics may negatively affect bone cell function.
RETRACTED: Alleviation of microplastic toxicity in soybean by arbuscular mycorrhizal fungi: Regulating glyoxalase system and root nodule organic acid
This retracted study investigated whether beneficial soil fungi could help soybean plants cope with microplastic contamination from polystyrene and polyethylene in soil. The original findings suggested that mycorrhizal fungi reduced microplastic toxicity by regulating the plant's stress response system and root chemistry. Note: this paper has been retracted and its conclusions should be treated with caution.