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Potential Impact Microplastic Polyethylene Terephthalate on Mice

Sarhad Journal of Agriculture 2024 4 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Marchel Putra Garfansa, Roy Hendroko Setyobudi, Iswahyudi Iswahyudi, Shazma Anwar, Damat Damat, Tony Liwang, Mardiana Sri Susanti, Diah Hermayanti, Meddy Setiawan, Thontowi Djauhari Nur Subchi, Dewi Mariyam, Yolla Muvika Ananda, Satriyo Krido Wahono, Adil Basir, Musrif Musrif, Anwar Saeed Khan

Summary

Researchers studied how polyethylene terephthalate (PET) microplastics affect mice when ingested, tracking where the particles end up in the body. They found that microplastics accumulated in various organs and caused measurable biological effects. The study adds to growing evidence that common plastic types found in food packaging may pose health risks when consumed.

Polymers
Models

Microplastic (MPs) pollution is an increasing global problem, creating deep concerns regarding its potential impact on human health.Numerous experiments have been conducted on living organisms to investigate the dispersion patterns of MPs.Furthermore, the extent of distribution and research conducted on MPs about mice still needs to be improved.This study aimed to determine the impact of PET (polyethylene terephthalate) MPs on mice's weight, feces, and appetite.Four feed experiments, P0 (pellet BR1), P1 (potato from Pujon Farm), P2 (potato mixed 300 µg PET), and P3 (potato mixed 600 µg PET), were investigated in this research.PET MPs at a dose of 600 µg had the worst impact on mice compared to the others.There were changes in eating performance, body weight, and mice feces in treatment P1 due to the MPs contained in them.Another consequence is anticipated: A reduction in microbial diversity in the intestines of mice, resulting in a fall in both feces and body weight of the mice.

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