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A review of the toxic effects of microplastics based on studies on mammals and mammalian cell lines
Summary
This review examined studies on the toxic effects of microplastics using mammals and mammalian cell experiments. Researchers found that adverse effects in animal studies appeared at relatively low daily doses of polystyrene and polyethylene microplastics. The study notes that cell-based experiments yielded variable results depending on the cell type tested, highlighting the complexity of understanding microplastic health impacts.
In vivo studies showed that adverse effects were observed at 0.01–0.15 mg day −1 for polystyrene microplastics and 0.125 mg day −1 for polyethylene microplastics. In vitro studies yielded variable results depending on the cell types.
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