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Article Tier 2 Detection Methods Environmental Sources Human Health Effects Marine & Wildlife Nanoplastics Remediation Sign in to save

Recent advances in microbial and enzymatic engineering for the biodegradation of micro- and nanoplastics

RSC Advances 2024 55 citations

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This review covers recent advances in using engineered enzymes and microbes to break down plastic pollution, including persistent plastics like polyethylene and polystyrene that are major sources of microplastics. Developing biological methods to degrade these materials matters for human health because microplastics have been linked to cancer risk and endocrine disruption, and reducing plastic pollution at the source could lower overall human exposure.

Body Systems

This review examines the escalating issue of plastic pollution, specifically highlighting the detrimental effects on the environment and human health caused by microplastics and nanoplastics. The extensive use of synthetic polymers such as polyethylene (PE), polyethylene terephthalate (PET), and polystyrene (PS) has raised significant environmental concerns because of their long-lasting and non-degradable characteristics. This review delves into the role of enzymatic and microbial strategies in breaking down these polymers, showcasing recent advancements in the field. The intricacies of enzymatic degradation are thoroughly examined, including the effectiveness of enzymes such as PETase and MHETase, as well as the contribution of microbial pathways in breaking down resilient polymers into more benign substances. The paper also discusses the impact of chemical composition on plastic degradation kinetics and emphasizes the need for an approach to managing the environmental impact of synthetic polymers. The review highlights the significance of comprehending the physical characteristics and long-term impacts of micro- and nanoplastics in different ecosystems. Furthermore, it points out the environmental and health consequences of these contaminants, such as their ability to cause cancer and interfere with the endocrine system. The paper emphasizes the need for advanced analytical methods and effective strategies for enzymatic degradation, as well as continued research and development in this area. This review highlights the crucial role of enzymatic and microbial strategies in addressing plastic pollution and proposes methods to create effective and environmentally friendly solutions.

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