We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Nanoplastic-induced cytotoxic and dysmetabolic effects in a steatosis-like model of HepG2 cells
No summary available — this paper's abstract is not included in the open metadata provided by the publisher. Learn why →
More Papers Like This
Nanoplastic-Induced Biological Effects In Vivo and In Vitro: An Overview
AI summary Read the abstract
Researchers reviewed how nanoplastics accumulate in and harm living organisms, finding that particle size, surface charge, exposure dose, and duration all influence toxicity — with smaller, charged particles penetrating cells more readily and chemical additives amplifying harm beyond the plastics themselves.
In vitro toxicity of polyethylene terephthalate nanoplastics (PET-NPs) in human hepatocarcinoma (HepG2) cell line
AI summary Read the abstract
Exposure of HepG2 human liver cells to PET nanoplastics for 72 hours caused dose-dependent reductions in cell viability, oxidative stress at higher concentrations, and significant DNA damage via comet assay, with an IC50 of 616.7 µg/mL. These in vitro findings indicate that PET nanoplastics — shed from the world's most widely used plastic — have genotoxic and cytotoxic potential in human liver tissue, warranting further investigation of carcinogenic risk at environmentally relevant concentrations.
Nanoplastic occurrence, transformation and toxicity: a review
AI summary Read the abstract
Researchers reviewed the environmental fate and biological toxicity of nanoplastics, finding that these sub-micron particles weather, aggregate, and accumulate contaminants in aquatic environments, and that ingestion by microbes, algae, invertebrates, and fish disrupts growth, reproduction, and behavior.
Disruption of lipid metabolism under plastic siege: Unraveling the toxic mechanisms of microplastics and nanoplastics
AI summary Read the abstract
Researchers reviewed how microplastics and nanoplastics disrupt lipid metabolism across multiple animal species, finding they inhibit digestive enzymes, alter gut microbiota, dysregulate fat storage and breakdown, and activate inflammatory signaling pathways — causing both acute and chronic metabolic damage.
The effects of nanoplastics on toxicity of metals and metal nanoparticles: molecular mechanisms and health effects
AI summary Read the abstract
Researchers reviewed how co-exposure to nanoplastics and heavy metals produces synergistic toxicity across multiple species and cell models, finding that nanoplastics enhance metal bioavailability and amplify oxidative stress, mitochondrial dysfunction, apoptosis, and gut dysbiosis more severely than equivalent microplastic co-exposures.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.