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Phenotypic profiling reveals polystyrene nanoplastics elicit sublethal and lethal effects on cellular morphology in rainbow trout gill epithelial cells

Environmental Science Nano 2025 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Lisbeth Díaz, Rebecca Klaper

Summary

Image-based phenotypic profiling revealed that polystyrene nanoplastics induced both sublethal and lethal morphological changes in rainbow trout gill epithelial cells at environmentally relevant concentrations, with dose-dependent effects on cell shape, nuclear integrity, and cytoskeletal organization.

Polymers

This work uses image-based profiling techniques to assess the environmental impacts of nanoplastics in fish gill cells at sublethal concentrations.

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