We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
A quality-by-design inspired approach to develop PET and PP nanoplastic test materials for use in in vitro and in vivo biological assays
AI summary Read the abstract
Researchers developed a quality-by-design approach for producing standardized PET and polypropylene nanoplastic test materials suitable for biological assays. The study provides a systematic framework for generating consistent nanoplastic particles for use in both in vitro and in vivo toxicity studies.
QbD-based production of PET and PP nanoplastics for biological assays.
More Papers Like This
Quality-by-design and current good practices for the production of test and reference materials for micro- and nano-plastic research
AI summary Read the abstract
Researchers outlined best practices for producing standardized reference materials used in micro- and nanoplastic research, covering both top-down fragmentation and bottom-up precipitation methods. They provided examples using common polymers like polyethylene, polypropylene, polystyrene, and PET across different size ranges. The study addresses a critical need in the field, since reliable reference materials are essential for validating the analytical methods used to detect and measure plastic pollution.
Preparation of Nanoplastic Particles as Potential Standards for the Study of Nanoplastics
AI summary Read the abstract
Researchers developed methods to prepare well-defined nanoplastic particles as potential reference standards for nanoplastic research, addressing the critical shortage of reliable materials for toxicity studies and analytical method validation. The study characterized the size, shape, and surface properties of the produced particles to confirm their suitability as standards.
Production, labeling, and applications of micro- and nanoplastic reference and test materials
AI summary Read the abstract
This study reviews methods for producing, labeling, and applying micro- and nanoplastic reference and test materials for research purposes. The researchers address the growing need for in-house production of standardized test materials, driven by challenges in extracting these particles from the environment and the limited range of commercially available options.
Production of detergent-free PET and biodegradable PBAT micro- and nanoplastics
AI summary Read the abstract
Researchers developed a detergent-free method for producing PET and biodegradable PBAT micro- and nanoplastic reference particles, enabling more standardized and ecologically relevant laboratory toxicity testing without surfactant interference.
Protocol for the production of micro- and nanoplastic test materials
AI summary Read the abstract
Scientists created a standardized protocol for producing well-characterized micro and nanoplastic test materials from polypropylene and PVC for use in health research. Current studies often use commercially available plastic beads that do not resemble real-world microplastics, making results hard to interpret. Having realistic, standardized test materials will improve the quality and comparability of future research on microplastic health effects.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.