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Polystyrene Microplastics‐Induced Thyroid Dysfunction in Mice: A Study of Gene Expression, Oxidative Stress, and Histopathological Changes

Veterinary Medicine and Science 2025 6 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Md. Sadequl Islam, Md. Kamruzzaman, UK Rima

Summary

In a mouse study, polystyrene microplastics caused thyroid dysfunction by altering gene expression, increasing oxidative stress, and damaging thyroid tissue. The findings show that microplastic exposure can disrupt the endocrine system, specifically the thyroid gland which controls metabolism and development. As environmental microplastic contamination increases, this research raises concerns about potential thyroid-related health problems in both animals and humans.

Polymers
Body Systems
Models

These findings underscore the potential risks that PS-MPs pose to thyroid health, with potential consequences for other veterinary species. As environmental contamination rises, veterinarians may encounter more endocrine disorders linked to PS-MPs, emphasising the need for further research and preventive measures.

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