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Polystyrene microplastic exposure alters redox and epithelial markers in porcine endometrial organoids
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This is a dataset, not a full study report. It contains lab measurements from pig uterus lining cells grown in dishes and exposed to polystyrene microplastic particles, with or without a compound called N-acetylcysteine, including gene activity and fluorescence data used in a related research paper.
This dataset contains processed numerical data from porcine endometrial organoids exposed to polystyrene microplastics with or without N-acetylcysteine. It includes qPCR ΔCt values, calculated ΔΔCt and relative gene expression, fluorescence measurements, group summaries, and statistical analyses for the main and supplementary figures.
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The effects of nanoplastics on adipose stromal cells from swine tissues
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Researchers assessed the effects of polystyrene nanoplastics on adipose stromal cells from pig tissue, finding reduced cell viability after prolonged exposure, increased inflammatory marker TNF-alpha, and elevated oxidative stress markers. These results suggest nanoplastics can disrupt cellular redox homeostasis in adipose tissue at environmentally relevant conditions.
Polystyrene Microsphere Exposure Disrupts Mitochondrial Redox and Induces Mitochondrial Impairment in Human Pluripotent NTERA-2 cl.D1 Cells.
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Human stem cells grown in a lab dish were exposed to tiny polystyrene plastic particles for 24 hours. The particles entered the cells, increased harmful molecules called reactive oxygen species, and disrupted the cells' mitochondria, the parts that produce energy, affecting their function and membrane health.
Investigation of potential toxic effects of nano- and microplastics on human endometrial stromal cells
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Researchers exposed human endometrial cells (uterine lining cells) to polystyrene nano- and microplastics and found that smaller particles (100 nanometers) were taken up most readily, accumulating in both the nucleus and cytoplasm. At higher concentrations, the nanoplastics reduced cell growth and triggered cell death. These findings suggest that nanoplastics could pose a risk to uterine health and potentially affect fertility and pregnancy outcomes.
Polystyrene microplastics induce biochemical and metabolism changes in human placental explants
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Researchers investigated the effects of polystyrene microplastics on human placental cells, finding that exposure altered biochemical pathways and metabolic activity. The results suggest that microplastics reaching the placenta can disrupt cellular functions important for fetal development.
Effect of polystyrene nanoplastics on in vitro maturation of pig cumulus-encosed oocytes
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Researchers exposed pig egg cells to polystyrene nanoplastics during laboratory maturation and found that while the eggs still completed their basic development stages, the nanoplastics significantly increased harmful reactive oxygen species levels. This oxidative stress reduced the quality of resulting embryos, as indicated by fewer cells per embryo, suggesting nanoplastic exposure could be a concern for reproductive health.
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