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Microplastics Unveiled: Origins, Environmental Risks and Biodegradation Solutions

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Millions of tons of plastic waste break down into tiny microplastics that now show up in our air, water, and soil, raising concerns for both ecosystems and human health. This review summarizes existing research on using bacteria and enzymes to break down these plastics, and highlights promising techniques like genetic engineering to make cleanup more effective. The findings point toward future solutions, though more research is still needed before these methods are widely usable.

Microplastic (MP) pollution has emerged as one of the most pressing global environmental challenges of the 21st century, threatening aquatic, terrestrial, and atmospheric ecosystems as well as human health. The widespread production and consumption of plastics have led to an unprecedented accumulation of plastic waste, with an estimated 9–23 million metric tons entering aquatic environments and 13–25 million metric tons accumulating in terrestrial ecosystems annually. A major consequence of plastic pollution is the proliferation of microplastics (MPs), primarily originating from polyethylene (PE), polypropylene (PP), polyvinyl chloride (PVC), and polyethylene terephthalate (PET). Owing to their remarkable environmental persistence, these contaminants are now pervasive across air, water, and soil ecosystems worldwide, posing profound ecological and public health challenges. Consequently, the effective mitigation and removal of MPs have emerged as critical priorities for sustainable environmental management and pollution control. Hence, their sources, risks, and means of removal are crucial concerns for sustainable environmental management and pollution abatement. The review provides a comprehensive overview of different degradation strategies, with particular emphasis on biodegradation, including whole-cell and enzymatic approaches. We further explore advanced strategies to enhance biodegradation efficacy, including bioaugmentation, biostimulation, genetic engineering, and system biology approaches. This review delivers a critical synthesis of biodegradation-based solutions for microplastic remediation, integrating mechanistic understanding, technological innovations, and emerging enhancement strategies into a unified perspective. By identifying major research gaps and translational challenges, it provides a roadmap for advancing next-generation biodegradation technologies capable of addressing the escalating environmental burden of microplastic pollution.

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