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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Environmental Sources
Human Health Effects
Nanoplastics
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[Exposure Pathways of Polystyrene Nanoplastics Mediate Their Cellular Distribution and Toxicity].
PubMed
2025
Jing Li,
Qixue Bao,
Zeyan Li,
Yuqin Yao,
Dongsheng Wu,
Lijun Peng,
Zhenmi Liu,
Lin Li,
Lin Li,
Ling Zhang
Summary
This study found that the route by which polystyrene nanoplastics enter the body determines which liver cell types accumulate the particles and what toxic effects occur, demonstrating that exposure pathway—not just dose—shapes nanoplastic toxicity in hepatic tissue.
Exposure pathways mediate the hepatic cell-type-specific distribution of PSNPs, thereby altering the downstream toxicological consequences induced by exposure to PSNPs.