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Microplastics and Nanoplastics: Impacts on Female Reproductive Health, Ovarian Function, and Genitourinary Disorders
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Researchers review evidence that microplastics and nanoplastics accumulate in ovarian tissue, follicular fluid, and placental material, linking exposure to ovarian toxicity, hormonal disruption, reduced fertility, and elevated endometriosis risk through oxidative stress and inflammation-mediated pathways.
Microplastics and nanoplastics (MNPs) are detected in ovarian tissue, follicular fluid, placenta, and the female genitourinary tract. Exposure is linked to ovarian toxicity, hormonal imbalance, reduced fertility, and increased risk of endometriosis and other GU disorders through oxidative stress, inflammation, and endocrine disruption. This perspective examines the mechanisms and proposes interaction-mediated therapeutic strategies under the Cythera Bio platform as targeted interventions.
More Papers Like This
Microplastics and Nanoplastics: Impacts on Female Reproductive Health, Ovarian Function, and Genitourinary Disorders
AI summary Read the abstract
Researchers reviewed evidence showing microplastics and nanoplastics accumulate in ovarian tissue, follicular fluid, and the female genitourinary tract, where they trigger oxidative stress, endocrine disruption, and inflammation linked to reduced fertility, hormonal imbalance, and elevated risk of endometriosis.
A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge
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This review examines what is known about how micro- and nanoplastics affect female reproductive health. Animal studies show these particles accumulate in ovarian tissue, disrupt hormones, and cause oxidative stress, leading to hormonal imbalances and ovarian damage, though research in humans is still limited.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
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This integrative review examines the impact of micro- and nanoplastics on female ovarian tissue, synthesizing animal model studies showing damage to follicular structures, increased oxidative stress, and disrupted reproductive hormone signaling.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
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This integrative review (in Portuguese) examines published evidence on the effects of micro- and nanoplastic exposure on female ovarian tissue morphology, finding disrupted folliculogenesis, oxidative stress, and hormonal interference reported across animal model studies.
Plastic Particles and Female Fertility: Pathways, Toxicity, and Analytical Challenges
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This review examines the pathways, toxicity mechanisms, and analytical challenges associated with microplastic and nanoplastic impacts on female fertility. Evidence from animal studies indicates that these particles can accumulate in ovaries and placental tissue, inducing oxidative stress, inflammation, and granulosa cell death that diminishes ovarian reserve. The study notes that microplastics have been confirmed in human placentas and umbilical cord blood, and may disrupt the hormonal axis governing reproduction.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.