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Microplastics and Nanoplastics: Impacts on Female Reproductive Health, Ovarian Function, and Genitourinary Disorders
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Researchers reviewed evidence showing microplastics and nanoplastics accumulate in ovarian tissue, follicular fluid, and the female genitourinary tract, where they trigger oxidative stress, endocrine disruption, and inflammation linked to reduced fertility, hormonal imbalance, and elevated risk of endometriosis.
Microplastics and nanoplastics (MNPs) are detected in ovarian tissue, follicular fluid, placenta, and the female genitourinary tract. Exposure is linked to ovarian toxicity, hormonal imbalance, reduced fertility, and increased risk of endometriosis and other GU disorders through oxidative stress, inflammation, and endocrine disruption. This perspective examines the mechanisms and proposes interaction-mediated therapeutic strategies under the Cythera Bio platform as targeted interventions.
More Papers Like This
Microplastics and Nanoplastics: Impacts on Female Reproductive Health, Ovarian Function, and Genitourinary Disorders
AI summary Read the abstract
Researchers review evidence that microplastics and nanoplastics accumulate in ovarian tissue, follicular fluid, and placental material, linking exposure to ovarian toxicity, hormonal disruption, reduced fertility, and elevated endometriosis risk through oxidative stress and inflammation-mediated pathways.
A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge
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This review examines what is known about how micro- and nanoplastics affect female reproductive health. Animal studies show these particles accumulate in ovarian tissue, disrupt hormones, and cause oxidative stress, leading to hormonal imbalances and ovarian damage, though research in humans is still limited.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
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This integrative review examines the impact of micro- and nanoplastics on female ovarian tissue, synthesizing animal model studies showing damage to follicular structures, increased oxidative stress, and disrupted reproductive hormone signaling.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
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This integrative review (in Portuguese) examines published evidence on the effects of micro- and nanoplastic exposure on female ovarian tissue morphology, finding disrupted folliculogenesis, oxidative stress, and hormonal interference reported across animal model studies.
Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
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This review summarizes research showing that micro- and nanoplastics can harm the female reproductive system in multiple ways, from reducing ovarian reserves and disrupting hormone balance to accumulating in the placenta and breast milk. Animal studies show these particles trigger oxidative stress and inflammation in reproductive tissues, and human studies have confirmed their presence in placental tissue and infant feces, raising concerns about effects on fertility and fetal development.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.