Papers

61,005 results
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Article Tier 2

Rethinking the relevance of microplastics as vector for anthropogenic contaminants: Adsorption of toxicants to microplastics during exposure in a highly polluted stream - Analytical quantification and assessment of toxic effects in zebrafish (Danio rerio)

Researchers exposed microplastics in a highly polluted stream to assess their role as contaminant vectors, then tested effects on zebrafish, finding that naturally contaminated microplastics had limited additional toxicity compared to the polluted water itself.

2021 The Science of The Total Environment 26 citations
Article Tier 2

Zebrafish as Model Organism in Aquatic Ecotoxicology: Current Trends and Future Perspectives

This review assessed zebrafish as model organisms for aquatic ecotoxicology, summarizing current trends and future directions in using Danio rerio to study the effects of environmental pollutants including microplastics. The authors highlight the zebrafish model's utility for integrating molecular, cellular, and whole-organism responses.

2023 IntechOpen eBooks 4 citations
Article Tier 2

Microplastics in freshwater ecosystems : effects and drivers

This thesis assessed how microplastic exposure affects freshwater microorganisms, macroinvertebrates, and other organisms in freshwater ecosystems, finding that microplastics are a pervasive contaminant of freshwater environments with unclear but potentially significant ecological impacts.

2024 Acta universitatis agriculturae Sueciae
Article Tier 2

Sorbed environmental contaminants increase the harmful effects of microplastics in adult zebrafish, Danio rerio

Researchers found that microplastics carrying sorbed environmental contaminants (DDE, BP-3, chlorpyrifos) caused greater harmful effects on adult zebrafish health and behavior than pristine microplastics alone, demonstrating their role as pollutant vectors.

2023 Aquatic Toxicology 14 citations
Article Tier 2

Effects of pristine or contaminated polyethylene microplastics on zebrafish development

Researchers examined the effects of both pristine and pollutant-contaminated polyethylene microplastics on zebrafish development through chronic exposure. The study assessed how microplastics, both alone and as carriers of adsorbed organic pollutants, affect developing fish. The findings provide new insights into how contaminated microplastics may create additional routes for toxic compounds to enter aquatic food webs.

2022 Chemosphere 66 citations
Article Tier 2

Structure activity toxicity of different micro-nanoplastics on developing Zebrafish (Danio rerio) based on individual polymer chemistry

This dissertation examined the toxicity of individual polymer chemistries—rather than generic microplastic mixtures—on zebrafish embryos and larvae, finding polymer-specific differences in developmental toxicity, behavioral disruption, and biochemical pathway activation across multiple plastic types.

2025 Rutgers University Community Repository (Rutgers University)
Article Tier 2

Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish ( Danio rerio )

Researchers studied the combined effects of microplastics and chemical contaminants like PCBs and methylmercury on zebrafish organs over three weeks of exposure. They found that microplastics carrying adsorbed contaminants produced the most significant effects, particularly on the liver, compared to either microplastics or contaminants alone. The results indicate that microplastics may act as carriers that increase the delivery of harmful chemicals to organisms' tissues.

2018 Environmental Research 406 citations
Article Tier 2

O Modelo Zebrafish e sua Contribuição ao Meio Ambiente

This Brazilian review examined zebrafish as a model organism for testing water quality and the toxicity of micropollutants including microplastics in wastewater. Zebrafish are increasingly used as a standard test system for evaluating the biological effects of microplastic exposure because their genetics and physiology closely mirror human responses.

2021
Article Tier 2

Effect assessment of nano- and microplastics in freshwater ecosystems

This doctoral thesis assessed the effects of nano- and microplastics on freshwater ecosystems, from individual species to community-level impacts. Freshwater sediments are known to accumulate these particles, and the research addresses critical gaps in understanding how long-term exposure at realistic concentrations affects aquatic communities.

2020 3 citations
Article Tier 2

Effects of microplastics on freshwater organisms: A laboratory approach

This thesis systematically examined how microplastics harm freshwater organisms both physically and by acting as carriers for chemical pollutants. The research found that both the physical presence of microplastics and the chemicals associated with them can negatively affect freshwater species.

2019 Universitätsbibliothek Tübingen
Article Tier 2

Study of the effects of nanoplastics ingestion in a freshwater fish ( Danio rerio )

Researchers exposed zebrafish to polystyrene nanoplastics and found evidence of intestinal damage, oxidative stress, and behavioral changes. The study adds to growing evidence that nanoplastics in freshwater environments can harm fish health, with potential implications for the health of ecosystems and fish-eating humans.

2021 Annals of Medicine 4 citations
Article Tier 2

Microplastics as an Emerging Threat to the Freshwater Fishes: a Review

This review examines microplastics as an emerging threat to freshwater fishes, covering their sources from cosmetics and plastic debris fragmentation, routes of entry including wastewater treatment plants, and documented toxic effects on fish physiology and behavior.

2022 International Journal of Biological Innovations 8 citations
Article Tier 2

The Role of Synthetic Polymers in the Aquatic Environment and Its Implications in Danio Rerio as a Model Organism

Exposing zebrafish to polystyrene microplastics combined with silver nanoparticles caused significantly more oxidative damage, tissue injury in gills and intestines, and higher mortality than either contaminant alone. The study demonstrates that microplastics can act as carriers that enhance the toxicity of co-pollutants like silver nanoparticles, a combination effect that is highly relevant to understanding real-world aquatic contamination where multiple pollutants co-occur.

2023 Apple Academic Press eBooks
Article Tier 2

Ingestão e efeitos morfofisiológicos dos microplásticos em espécies de peixes da Amazônia Central

This Brazilian thesis investigates microplastic ingestion and its effects on fish from the Amazon basin, one of the world's most biodiverse freshwater systems. Given that aquatic organisms in even remote areas are exposed to microplastics, the research highlights risks to Amazon fish diversity and the potential for microplastics to disrupt aquatic food webs in previously pristine ecosystems.

2022
Article Tier 2

Environmental Impact of Microplastics in Aquatic Ecosystems: A Review of Current Research and Future Directions

This review examines microplastic pollution in aquatic ecosystems, covering chemical, biological, and ecological processes beyond simple physical contamination and identifying priority areas for future research directions.

2025 Indus journal of bioscience research.
Article Tier 2

Uptake, removal and trophic transfer of fluorescent polyethylene microplastics by freshwater model organisms: the impact of particle size and food availability

Researchers used fluorescent polyethylene microplastics of different sizes to track how they move through a freshwater food chain from algae to water fleas to zebrafish. They found that smaller particles were ingested and transferred more readily between organisms, and that food availability influenced how many microplastics accumulated. The study demonstrates that microplastics can move up the food chain and that particle size plays a key role in how they are transported through aquatic ecosystems.

2024 Aquatic Toxicology 8 citations
Article Tier 2

Comprehensive review of ecological risks and toxicity mechanisms of microplastics in freshwater: Focus on zebrafish as a model organism

This comprehensive review examines how microplastics affect zebrafish, a widely used laboratory model, covering impacts on the gut, liver, reproductive system, nervous system, and immune function. Researchers found that microplastics can cause oxidative stress, inflammation, and disruption of gut bacteria across multiple organ systems. The review highlights that zebrafish studies provide valuable insights into the biological mechanisms by which microplastics may affect freshwater organisms and, potentially, human health.

2025 Aquatic Toxicology 4 citations
Article Tier 2

Accumulation and Distribution of Fluorescent Microplastics in the Early Life Stages of Zebrafish

Researchers tracked the accumulation and distribution of fluorescent microplastics in early life stages of a freshwater organism, finding that microplastics were taken up and distributed across body tissues. The results help explain how microplastics accumulate in young aquatic organisms and potentially affect their development.

2021 Journal of Visualized Experiments 5 citations
Article Tier 2

Research Progress of Zebrafish Model in Aquatic Ecotoxicology

This review examines how zebrafish are used as model organisms to study the toxic effects of environmental pollutants in water, including microplastics. Zebrafish are ideal because they reproduce quickly, are inexpensive to maintain, and allow researchers to study effects at the genetic, cellular, and whole-organism level. The paper provides a reference guide for scientists choosing model animals for aquatic toxicology research.

2023 Water 48 citations
Article Tier 2

Biological alterations of polyvinyl chloride (PVC) microplastics on Danio rerio at environmentally relevant concentrations – risk assessment

Researchers assessed the toxic effects of polyvinyl chloride microplastics at environmentally relevant concentrations on zebrafish over 20 days. The study found that PVC microplastics accumulated in the gastrointestinal tract and caused biological alterations including changes in growth, behavior, and tissue integrity, highlighting potential ecological risks at realistic exposure levels.

2026 Fish Physiology and Biochemistry
Article Tier 2

Microplastics in Aquatic Environments and Their Toxicological Implications for Fish

This review summarizes research on microplastic occurrence in freshwater and marine environments and the toxicological risks they pose to fish, examining both direct physical effects and the role of plastics as vectors for chemical pollutants. The authors highlight that freshwater fish are particularly vulnerable given the high loads of microplastics in rivers receiving wastewater.

2016 InTech eBooks 61 citations
Article Tier 2

The Role of Danio rerio in Understanding Pollutant-Induced Gut Microbiome Dysbiosis in Aquatic Ecosystems

This review examines how freshwater pollutants—including pesticides, heavy metals, antibiotics, dyes, and microplastics—disrupt gut microbiome composition in zebrafish and other aquatic animals. It highlights the zebrafish model as a key tool for understanding pollutant-driven microbiome dysbiosis and its metabolic consequences.

2025 Toxics
Article Tier 2

Investigations into the Roles of Organisms on Environmental Plastic Pollution

This thesis investigated the roles of organisms in environmental plastic pollution, examining how marine and freshwater animals ingest microplastics and how they may transfer them through food webs. The work contributes to understanding the ecological consequences of plastic contamination in aquatic ecosystems.

2021 Maryland Shared Open Access Repository (USMAI Consortium)
Article Tier 2

Qualitative and quantitative analysis of accumulation and biodistribution of polystyrene nanoplastics in zebrafish (Danio rerio) via artificial freshwater

Researchers developed MALDI-TOF mass spectrometry methods to accurately track polystyrene nanoplastic accumulation and biodistribution across zebrafish tissues after waterborne exposure, enabling precise quantitative analysis of nanoplastic uptake.

2023 Environmental Science Nano 8 citations