Papers

61,005 results
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Article Tier 2

An Overview into Polyethylene Terephthalate (PET) Hydrolases and Efforts in Tailoring Enzymes for Improved Plastic Degradation

This review examines the discovery and engineering of PET-degrading enzymes including PETase and cutinase variants, discussing protein engineering strategies to improve catalytic efficiency and thermostability for practical biodegradation of polyethylene terephthalate plastic waste.

2022 International Journal of Molecular Sciences 120 citations
Article Tier 2

Biodegradation of Plastic and the Role of Microbial Enzymes in Plastic Waste Management

This review examines how microbial enzymes, particularly PET hydrolases and oxidative enzymes, can depolymerize and break down common plastic polymers through biological degradation. The study suggests that enzymatic approaches to plastic waste management offer a promising complement to mechanical and chemical recycling, though optimizing enzyme activity and scaling up the process remain key challenges.

2026 International Journal of Education Management and Technology
Article Tier 2

Microbial and Enzymatic Degradation of Plastic Waste in Water

This review surveys microbial and enzymatic pathways for degrading plastic waste in water, cataloging enzymes such as PETases and cutinases along with the microorganisms that produce them. The authors assess current limitations of biological degradation rates and discuss how enzyme engineering and synthetic microbial consortia could accelerate plastic breakdown.

2024
Article Tier 2

The Current State of Research on PET Hydrolyzing Enzymes Available for Biorecycling

This review summarizes the current state of PET-hydrolyzing enzymes, including thermophilic cutinases and engineered variants, that are candidates for enzymatic biorecycling of PET plastic waste back into reusable monomers.

2021 Catalysts 91 citations
Article Tier 2

Microbial enzymes for the recycling of recalcitrant petroleum‐based plastics: how far are we?

This review examines the progress in identifying microbial enzymes capable of breaking down petroleum-based plastics like polyethylene, polystyrene, polyurethane, and PET. Researchers highlight recent advances in using polyester-degrading enzymes to recover raw materials from PET waste through biocatalytic recycling. The study discusses the potential and remaining challenges of using biological approaches to address the growing global problem of plastic waste accumulation.

2017 Microbial Biotechnology 788 citations
Article Tier 2

Enzymatic Remediation of Polyethylene Terephthalate (PET)–Based Polymers for Effective Management of Plastic Wastes: An Overview

Enzymatic approaches for remediating PET-based plastic waste were reviewed, covering PETase and related enzymes that can break PET into reusable monomers. Enzyme engineering strategies to improve thermostability and catalytic efficiency are discussed as a pathway to scalable biological PET recycling.

2020 Frontiers in Bioengineering and Biotechnology 193 citations
Article Tier 2

Engineered polyethylene terephthalate hydrolases: perspectives and limits

This review examines progress in engineering enzymes that can break down PET plastic, the material used in most beverage bottles and synthetic textiles. Researchers found that while significant advances have been made through protein engineering and machine learning, no enzyme yet exists that can efficiently degrade the crystalline form of PET found in real-world waste. The study outlines the key challenges remaining before enzymatic plastic recycling can work at industrial scale, including handling microplastic contamination.

2024 Applied Microbiology and Biotechnology 27 citations
Article Tier 2

Hydrolytic Degradation of Polyethylene Terephthalate by Cutinase Enzyme Derived from Fungal Biomass–Molecular Characterization

Researchers isolated cutinase and lipase enzymes from Aspergillus tamarii and Penicillium crustosum fungi and demonstrated their ability to catalyze hydrolytic degradation of PET plastic, offering a potential biological route for plastic waste breakdown.

2021 Biointerface Research in Applied Chemistry 37 citations
Article Tier 2

Application of PETase in Plastic Biodegradation and Its Synthesis

This review examines how PETase enzymes can be used to biodegrade plastic waste, particularly polyethylene terephthalate, which is one of the most widely used plastics globally. Researchers discuss recent advances in modifying PETase enzymes for improved efficiency and establishing sustainable synthesis platforms. The study suggests that enzymatic biodegradation offers a promising biological solution to the growing plastic pollution crisis.

2024 E3S Web of Conferences 2 citations
Article Tier 2

Current knowledge on enzymatic PET degradation and its possible application to waste stream management and other fields

This review distinguished between enzymatic PET surface modification (useful for fiber treatment) and enzymatic PET degradation (needed for waste management), cataloguing the hydrolases capable of each function and the conditions required. The authors evaluate the prospects for deploying PET-degrading enzymes in industrial plastic waste streams.

2019 Applied Microbiology and Biotechnology 576 citations
Article Tier 2

Fungal Enzymes as Catalytic Tools for Polyethylene Terephthalate (PET) Degradation

This review examines the potential of fungal enzymes, including esterases, lipases, and cutinases, to break down polyethylene terephthalate (PET) plastic waste. Researchers surveyed the literature on how these biocatalysts work and their effectiveness compared to more widely studied bacterial enzymes. The study suggests that fungal enzymes offer a promising and underexplored avenue for developing eco-friendly PET degradation technologies.

2021 Journal of Fungi 67 citations
Article Tier 2

A sequence- and structure-based characterization of microbial enzymes identifies P. stutzeri as a plastic-degrading species

Researchers characterized microbial enzymes with potential plastic-degrading capabilities, focusing on PETase and MHETase enzyme systems. The study identified Pseudomonas stutzeri as a species with notable plastic degradation potential, contributing to the growing understanding of biological approaches for addressing plastic pollution through enzymatic bioremediation.

2024 2 citations
Article Tier 2

Determinants for an Efficient Enzymatic Catalysis in Poly(Ethylene Terephthalate) Degradation

This review covers the current state of enzymatic PET degradation, examining which enzymes act on PET, how protein engineering has improved their activity, and what challenges remain before enzymatic recycling can be deployed at industrial scale.

2023 Catalysts 19 citations
Article Tier 2

Current advances in the structural biology and molecular engineering of PETase

The study reviews advances in the structural biology and molecular engineering of PETase, an enzyme from the bacterium Ideonella sakaiensis that can break down PET plastic at moderate temperatures. Researchers discuss efforts to enhance the enzyme's activity and thermal stability through protein engineering, which could lead to more efficient and environmentally friendly PET recycling strategies.

2023 Frontiers in Bioengineering and Biotechnology 42 citations
Article Tier 2

Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET

This review discusses the role of enzymatic biocatalysis in PET plastic degradation, examining how the discovery of PETase and subsequent enzyme engineering have advanced biodegradation as an alternative to chemical and mechanical recycling for one of the most produced plastics globally.

2021 International Journal of Molecular Sciences 97 citations
Article Tier 2

Microbes in Plastic Degradation

This review examines how microorganisms can break down common plastics like polyethylene and PET through enzymatic processes. Researchers summarized the key bacterial and fungal species capable of degrading plastics and the conditions that affect degradation rates. The study highlights that while microbial plastic degradation is promising, natural breakdown is slow and more research is needed to make biological solutions practical at scale.

2024 International Journal of Current Science Research and Review 4 citations
Article Tier 2

Microbial Degradation of (Micro)plastics: Mechanisms, Enhancements, and Future Directions

This review examines how microorganisms can break down microplastics using enzymes like PETase and laccases, offering a more environmentally friendly alternative to other cleanup methods. While microbial degradation holds promise for reducing microplastic pollution and its associated health risks, current efficiency is too low for large-scale application and needs further improvement.

2024 Fermentation 54 citations
Article Tier 2

Recent advances in enzyme engineering for improved deconstruction of poly(ethylene terephthalate) (PET) plastics

This review covers recent progress in engineering enzymes that can break down PET plastic, the material used in water bottles and food containers. While natural enzymes that digest PET have been discovered, they are not yet fast or durable enough for industrial-scale recycling. Advances in protein engineering, directed evolution, and computational design are steadily improving these enzymes, which could eventually provide a sustainable way to recycle PET and reduce microplastic pollution at its source.

2025 Communications Materials 7 citations
Article Tier 2

A review on microbial bioremediation of polyethylene terephthalate microplastics

This review focuses on microbial biodegradation of PET microplastics — the plastic used in bottles and synthetic textiles — detailing the specific enzymes (PETase and MHETase) that bacteria use to break the polymer down into its chemical building blocks. Biological degradation offers a lower-energy, more environmentally gentle alternative to chemical recycling or landfill, and understanding the microbial mechanisms involved is key to developing scalable bioremediation solutions for one of the most pervasive microplastic types.

2024 Environmental Quality Management 2 citations
Article Tier 2

Potential Use of Microbial Enzymes for the Conversion of Plastic Waste Into Value-Added Products: A Viable Solution

This review examines microbial enzymes capable of hydrolyzing PLA-PET mixed plastic waste, evaluating enzymatic degradation pathways and the potential for enzyme-based plastic valorization as an economically viable alternative to chemical recycling.

2021 Frontiers in Microbiology 66 citations
Article Tier 2

Enzymatic Degradation of PET plastic

This study tested commercial-grade enzymes for degrading PET plastic and found that enzymatic degradation was effective at laboratory scale but faced challenges for real-world application. Scaling up enzymatic PET recycling could reduce the persistence of plastic waste that eventually fragments into microplastics in the environment.

2023 ARPHA Conference Abstracts
Article Tier 2

Enzymatic PET Degradation

This review examines enzymatic degradation of PET (polyethylene terephthalate), the plastic used in bottles and polyester clothing, as a promising pathway for breaking down this persistent polymer. Advances in engineering more efficient PET-degrading enzymes could enable industrial-scale biological recycling and reduce the environmental accumulation of PET microplastics.

2019 CHIMIA International Journal for Chemistry 50 citations
Article Tier 2

An archaeal lid-containing feruloyl-esterase degrades polyethylene terephthalate (PET)

This study identified the first archaeal enzyme capable of degrading PET plastic, characterizing its structure and biochemical properties. Expanding the diversity of organisms with PET-degrading enzymes could accelerate the development of biological strategies for breaking down the microplastics contaminating marine and terrestrial environments.

2023
Article Tier 2

Current Knowledge on Polyethylene Terephthalate Degradation by Genetically Modified Microorganisms

This review covers genetically modified microorganisms engineered to degrade polyethylene terephthalate, examining how bioengineering of enzymes such as PETase and enhanced expression systems can overcome the low biodegradation rates of wild-type microorganisms toward this ubiquitous plastic.

2021 Frontiers in Bioengineering and Biotechnology 92 citations