Papers

61,005 results
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Article Tier 2

On the Generation, Impact and Removal of Antibiotic Resistance in the Water Environment

This review explains how antibiotic resistance develops and spreads through water environments — including rivers, groundwater, and wastewater. The findings are relevant to microplastics because plastic particles in water are known to accumulate antibiotic-resistant bacteria, potentially accelerating the spread of drug resistance through aquatic systems.

2023 BIO Web of Conferences 1 citations
Article Tier 2

Modeling Antimicrobial Resistance Spread in Riverine Ecosystems: A Multidisciplinary Approach

Researchers developed a multidisciplinary modeling framework to simulate antimicrobial resistance (AMR) spread in riverine ecosystems, incorporating wastewater discharge, agricultural runoff, and microplastic-associated resistance gene transfer. The model predicted AMR gene concentrations along river corridors and identified intervention points for reducing environmental AMR dissemination.

2025 International Journal of Emerging Research in Science Engineering and Management
Article Tier 2

Antibiotic resistance genes in treated wastewater and in the receiving water bodies: A pan-European survey of urban settings

Researchers surveyed 16 wastewater treatment plants across ten European countries and found that antibiotic resistance genes — DNA instructions that help bacteria survive antibiotics — are consistently released into rivers receiving treated wastewater. The study found that plants with more biological treatment steps had lower levels of these genes, suggesting that upgrading treatment infrastructure could reduce the spread of antibiotic resistance in the environment.

2019 Water Research 341 citations
Review Tier 2

Occurrence of Antimicrobial Resistance in the Environment in Germany, Austria, and Switzerland: A Narrative Review of Existing Evidence

A narrative review synthesized evidence on antibiotic resistance in environmental settings across Germany, Austria, and Switzerland, documenting that resistant bacteria and resistance genes are widespread in soil, water, and wastewater systems. The review identifies agricultural antibiotic use and wastewater discharge as the dominant pathways driving environmental antibiotic resistance in these three countries.

2022 Microorganisms 10 citations
Article Tier 2

Impact of wastewater treatment plant effluent discharge on the antibiotic resistome in downstream aquatic environments: a mini review

This review summarizes how wastewater treatment plants release antibiotic-resistant bacteria and resistance genes into rivers and lakes through their treated water. Current treatment processes cannot fully remove these resistance factors, allowing them to spread in downstream water bodies and potentially reach humans through drinking water and the food chain. The review is relevant to microplastics research because microplastics in wastewater can serve as surfaces where resistant bacteria grow and spread.

2023 Frontiers of Environmental Science & Engineering 31 citations
Article Tier 2

Potential of waterbodies as a reservoir ofEscherichia colipathogens and the spread of antibiotic resistance in the Indonesian aquatic environment

This review analyzes the factors driving the spread of pathogenic Escherichia coli and antibiotic-resistant bacteria in Indonesian aquatic environments, including antibiotic misuse, inadequate waste treatment, and poor industrial waste management. Indonesian rivers serve as vectors for both pathogenic E. coli and antimicrobial resistance genes, posing significant public health risks.

2023 Journal of Water Sanitation and Hygiene for Development 4 citations
Article Tier 2

Evolution and Emergence of Antibiotic Resistance in Given Ecosystems: Possible Strategies for Addressing the Challenge of Antibiotic Resistance

This review traces the history of antibiotic resistance and examines how it evolves and spreads across aquatic and terrestrial ecosystems. Researchers discuss the ecological roles of antibiotics and the modern tools used to identify resistant organisms in various environments. The study highlights the ecotoxicological impact of antibiotic-resistant bacteria and explores potential strategies, including environmental monitoring, to address this growing public health challenge.

2022 Antibiotics 54 citations
Article Tier 2

Emerging Antibiotic Resistance Genes in the Aquatic Ecosystems: a Review

A review of 30 studies found antibiotic resistance genes (ARGs) widely distributed across aquatic ecosystems — in surface water, groundwater, wastewater, and notably on plastic and microplastic debris in these environments. Microplastics appear to provide favorable surfaces for the growth and exchange of resistant bacteria, making plastic pollution a potential vector for spreading antibiotic resistance. The findings highlight an understudied intersection between microplastic contamination and the global antibiotic resistance crisis.

2023 Borneo AKademika
Article Tier 2

Impact of Anthropogenic Activities on the Dissemination of ARGs in the Environment—A Review

This review examined how anthropogenic activities, including operation of wastewater treatment plants and agricultural practices, contribute to the spread of antimicrobial resistance genes in the environment. The study discusses how microplastics and other pollutants may serve as carriers and facilitators for the dissemination of antibiotic resistance, compounding the global public health challenge of antimicrobial resistance.

2022 International Journal of Environmental Research and Public Health 55 citations
Article Tier 2

The problem of contamination of aquatic ecosystems with antibiotics (a review)

This review examines the contamination of aquatic ecosystems by antibiotics, synthesizing global data on risks associated with antibiotic presence in ocean and freshwater environments, including effects on aquatic organisms and the promotion of antibiotic resistance. The authors assess quantitative and qualitative contamination using bivalves as bioindicators and evaluate the spread of resistance genes through aquatic biocenoses.

2023 Ribogospodarsʹka nauka Ukraïni 3 citations
Article Tier 2

Antimicrobial and the Resistances in the Environment: Ecological and Health Risks, Influencing Factors, and Mitigation Strategies

This review examines how antimicrobial contamination in the environment contributes to the growing problem of antimicrobial resistance. Researchers found that residual antimicrobials from medical and agricultural use continuously enter ecosystems, promoting the spread of resistant bacteria and resistance genes. The study highlights environmental factors that are often overlooked and discusses strategies for reducing antimicrobial pollution and limiting resistance spread.

2023 Toxics 58 citations
Article Tier 2

Flushed and Forgotten: Antimicrobial Resistance from Wastewater Perspective

This review examines antimicrobial resistance in wastewater streams, covering the role of microplastics as vectors for resistance genes and bacteria, and discussing treatment strategies to reduce the release of resistant organisms from wastewater facilities into aquatic environments.

2025 IntechOpen eBooks
Article Tier 2

Antibiotic and Non-Antibiotic Determinants of Antimicrobial Resistance: Insights from Water Ecosystems

This review explains how non-antibiotic pollutants like heavy metals, biocides, and microplastics are contributing to antibiotic resistance in water systems, beyond the well-known problem of antibiotic overuse. Wastewater treatment plants are hotspots where these pollutants interact with bacteria, promoting the spread of resistance genes through mobile genetic elements. The findings are concerning for human health because drug-resistant bacteria from water environments can ultimately reach people through drinking water and food.

2024 ACS ES&T Water 10 citations
Review Tier 2

Proclivities for prevalence and treatment of antibiotics in the ambient water: a review

This review critically examines the prevalence of antibiotics in ambient water systems and the challenges of treating antibiotic-contaminated water. Researchers found that antibiotic resistance in water environments has emerged as a major public health concern, driven by pharmaceutical runoff and inadequate wastewater treatment. The study evaluates various treatment technologies and emphasizes the need for better monitoring and removal strategies to address this growing threat to water quality.

2020 npj Clean Water 161 citations
Article Tier 2

Dissemination Of Antibiotic Resistance Via Wastewater And Surface Water

This review examined how antibiotic-resistant bacteria spread through wastewater and surface water, noting that microplastics in wastewater can carry resistant bacteria into the environment. Antibiotic resistance is a growing public health crisis, and plastic pollution is one pathway accelerating its spread in waterways.

2021 Research Repository (Delft University of Technology)
Article Tier 2

The Sources and Potential Hosts Identification of Antibiotic Resistance Genes in the Yellow River, Revealed by Metagenomic Analysis

Researchers used metagenomic analysis to characterize antibiotic resistance genes in the Yellow River, identifying their sources and potential bacterial hosts, finding that resistance genes against colistin and carbapenems were present and tracing their origins to agricultural, municipal, and industrial inputs along the river.

2022 International Journal of Environmental Research and Public Health 6 citations
Article Tier 2

Antimicrobial Resistance in Exploited Estuaries: Some Overlooked Environmental Contaminants and Microbial Niches Might Act as Drivers

This review examined antimicrobial resistance in exploited estuaries, identifying overlooked environmental contaminants including antibiotics, heavy metals, and biocides as drivers of resistance gene spread in estuarine microbiomes with implications for human health and food safety.

2023 Environmental Toxicology and Chemistry 3 citations
Article Tier 2

The Role of the Environment (Water, Air, Soil) in the Emergence and Dissemination of Antimicrobial Resistance: A One Health Perspective

This review examines how water, soil, and air act as reservoirs for antibiotic-resistant bacteria, with microplastics highlighted as one of several agents that help spread drug-resistant genes across environments. The findings matter for human health because microplastics can carry antibiotic-resistant bacteria from wastewater and agricultural runoff into water supplies and food systems.

2025 Antibiotics 16 citations
Article Tier 2

Comparison of Antibiotic Resistance of Escherichia coli Populations from Water or Sediment in Rivers Environments

This study compared antibiotic-resistant E. coli in river water and sediment, examining how bacteria form biofilms and stabilize resistance in these environments. Microplastics in aquatic environments are known to promote biofilm formation and concentrate antibiotic resistance genes, amplifying this public health concern.

2023 Preprints.org 1 citations
Article Tier 2

Comparison of the Antibiotic Resistance of Escherichia coli Populations from Water and Biofilm in River Environments

Researchers compared antibiotic resistance in E. coli populations from river water versus sediment and biofilm samples at locations upstream and downstream of urban areas in Austria. They found that biofilm and sediment environments harbored bacteria with higher rates of antibiotic resistance compared to the water column. The study suggests that river biofilms may serve as reservoirs for antibiotic-resistant bacteria, with implications for how pollutants including microplastics interact with microbial communities.

2024 Pathogens 12 citations
Article Tier 2

Antimicrobial Resistance Development Pathways in Surface Waters and Public Health Implications

Researchers evaluated the pathways through which antibiotic-resistant bacteria develop and spread in surface waters, identifying healthcare facilities, wastewater, agricultural runoff, and wildlife as major vehicles. The study found that antibiotic residues, heavy metals, and even climate change drive the emergence of resistance in aquatic environments. The findings highlight that surface water contamination poses a growing public health threat, particularly for food and animal handlers who face higher exposure risk.

2022 Antibiotics 86 citations
Article Tier 2

Microplastics and Antibiotic Resistance: The Magnitude of the Problem and the Emerging Role of Hospital Wastewater

This review examines how microplastics in water can carry antibiotic-resistant bacteria and spread resistance genes, especially through hospital wastewater. Microplastics provide a surface where bacteria easily form colonies and share resistance genes, creating a potential threat to human health. The authors call for better wastewater management to reduce this emerging risk.

2023 International Journal of Environmental Research and Public Health 71 citations
Article Tier 2

Transmission and Evolution of Antibiotic Resistance Genes and Antibiotic-Resistant Bacteria in Animals, Food, Humans and the Environment

This research review shows that antibiotic-resistant bacteria and their genes are now found everywhere—in people, animals, food, and the environment—not just in hospitals like we used to think. The bacteria can easily share their resistance genes with each other, allowing "superbugs" to spread rapidly between different environments. This matters because it means antibiotic-resistant infections are becoming harder to treat and can reach us through multiple pathways, making it crucial to tackle this problem across all areas of health and the environment at once.

2026 Microorganisms
Article Tier 2

Abundance and Antimicrobial Resistance of Three Bacterial Species along a Complete Wastewater Pathway

A year-long study of a Swedish wastewater pathway found that antibiotic-resistant bacteria were most abundant in hospital wastewater and that resistance profiles mirrored local antibiotic consumption. Wastewater treatment plants also process microplastics, and understanding how bacteria move through these systems is relevant to the plastisphere's role in spreading resistance.

2019 Microorganisms 44 citations