Papers

20 results
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Article Tier 2

Melatonin-Mediated Abiotic Stress Tolerance in Plants

This review examines how melatonin, a molecule found in all living organisms, helps plants cope with environmental stresses like drought, extreme temperatures, salinity, and heavy metal contamination. Researchers found that melatonin works by neutralizing harmful reactive oxygen species and activating plant defense pathways. The study suggests that melatonin-based treatments could help improve crop resilience in the face of increasing environmental challenges, including soil pollution.

2022 Frontiers in Plant Science 149 citations
Article Tier 2

Melatonin Alleviates Antimony Toxicity by Regulating the Antioxidant Response and Reducing Antimony Accumulation in Oryza sativa L.

Researchers investigated whether melatonin, a natural antioxidant compound, could help rice plants cope with toxic antimony contamination. They found that applying melatonin reduced antimony uptake, decreased oxidative damage, and improved rice growth under antimony stress conditions. The study suggests that melatonin treatments could be a practical strategy for growing rice in soils contaminated with heavy metals.

2023 Antioxidants 22 citations
Article Tier 2

Comparative Physiological and Transcriptomics Profiling Provides Integrated Insight into Melatonin Mediated Salt and Copper Stress Tolerance in Selenicereus undatus L.

Researchers studied how the hormone melatonin helps dragon fruit plants tolerate salt and copper stress. When both stressors were combined, plant growth dropped by about 54 percent, but melatonin treatment restored growth by roughly 73 percent. Gene analysis revealed that melatonin activates stress defense pathways and secondary metabolite production, identifying key genes that could be targets for developing more stress-resistant crop varieties.

2024 Plants 5 citations
Article Tier 2

Exogenous Melatonin Application Alleviates Microplastics and Cadmium‐Induced Phytotoxicity in Maize ( Zea mays L.) Plants: Insights From Physiological and Metabolomic Analyses

Researchers investigated whether exogenous melatonin could alleviate the combined phytotoxicity of microplastics and cadmium in maize plants. The study found that melatonin application reduced oxidative damage and improved plant growth under co-contamination stress, suggesting that melatonin may serve as a biostimulant to help crops cope with the increasingly common co-occurrence of microplastics and heavy metals in agricultural soils.

2025 Journal of Pineal Research 1 citations
Article Tier 2

Involvement of Nitric Oxide and Melatonin Enhances Cadmium Resistance of Tomato Seedlings through Regulation of the Ascorbate–Glutathione Cycle and ROS Metabolism

Researchers found that melatonin and nitric oxide work together to enhance cadmium stress tolerance in tomato seedlings, with melatonin acting partly through nitric oxide signaling to reduce oxidative damage and support seedling growth under heavy metal stress.

2023 International Journal of Molecular Sciences 25 citations
Article Tier 2

Melatonin reduces nanoplastic uptake, translocation, and toxicity in wheat

Researchers investigated whether melatonin could reduce the harmful effects of polystyrene nanoplastics on wheat plants. They found that melatonin application significantly decreased nanoplastic uptake by roots and their transport to shoots by regulating aquaporin gene expression and activating antioxidant defense systems. The study suggests that melatonin may serve as a protective agent to help mitigate nanoplastic toxicity in crops.

2021 Journal of Pineal Research 75 citations
Article Tier 2

Reclaiming multi-contaminated soil: melatonin alleviates cadmium and microplastic toxicity to restore rice growth and yield

Researchers investigated whether melatonin could mitigate the combined toxicity of cadmium and microplastics in agricultural soils to restore rice growth and yield. The study found that melatonin treatment modulated plant physiological function, reduced cadmium uptake, and improved soil properties, offering a promising approach to help crops withstand multi-contaminant stress from both heavy metals and microplastics.

2026 RSC Advances
Article Tier 2

Interpreting the potential of biogenic TiO2 nanoparticles on enhancing soybean resilience to salinity via maintaining ion homeostasis and minimizing malondialdehyde

Researchers found that titanium dioxide nanoparticles derived from plants helped soybean crops tolerate salt stress by improving water retention, boosting antioxidant defenses, and keeping beneficial minerals like potassium in balance — offering a potential tool for farming in salt-affected soils.

2025 Scientific Reports 14 citations
Article Tier 2

Exogenous spermine alleviates the negative effects of combined salinity and paraquat in tomato plants by decreasing stress-induced oxidative damage

Exogenous spermine application reduced leaf damage and improved photosynthetic function and growth of tomato plants under combined salinity and paraquat herbicide stress, with the protective effect attributed to decreased hydrogen peroxide and malondialdehyde accumulation.

2023 Frontiers in Plant Science 24 citations
Article Tier 2

Melatonin Supplementation during In Vitro Maturation of Porcine Oocytes Alleviates Oxidative Stress and Endoplasmic Reticulum Stress Induced by Imidacloprid Exposure

Researchers found that the neonicotinoid insecticide imidacloprid adversely affected porcine oocyte maturation by increasing oxidative stress, endoplasmic reticulum stress, and apoptosis. The study demonstrated that melatonin supplementation during in vitro maturation was able to restore oocyte quality and embryo development outcomes compromised by imidacloprid exposure, suggesting melatonin has protective properties against pesticide-induced reproductive toxicity.

2023 Animals 11 citations
Article Tier 2

Titanium dioxide nanoparticles alleviates polystyrene nanoplastics induced growth inhibition by modulating carbon and nitrogen metabolism via melatonin signaling in maize

Researchers found that titanium dioxide nanoparticles can help protect maize plants from the growth-inhibiting effects of polystyrene nanoplastics. The protective mechanism works through the plant hormone melatonin, which regulates carbon and nitrogen metabolism when the nanoparticles are present. The study suggests that certain nanoparticles could potentially be used as agricultural tools to help crops cope with nanoplastic contamination in soil.

2024 Journal of Nanobiotechnology 29 citations
Article Tier 2

Unraveling the Complex Physiological, Biochemical, and Transcriptomic Responses of Pea Sprouts to Salinity Stress

Researchers investigated the physiological, biochemical, and transcriptomic responses of pea sprouts to high salinity stress, analyzing the ascorbic acid-glutathione cycle, endogenous hormone levels, metabolite profiles, and gene expression patterns. The study revealed coordinated redox-metabolic adjustments and transcriptome reprogramming that mediate ionic stress tolerance in this nutrient-rich crop.

2025 Genes
Article Tier 2

Synergistic integration of melatonin, copper nanoparticles, and Bacillus velezensis mitigates anthracnose and microplastic stress in chili: A novel eco-friendly strategy for sustainable crop protection

Researchers combined melatonin, copper nanoparticles, and a beneficial bacterium (Bacillus velezensis) to simultaneously protect chili pepper plants from both fungal disease and microplastic stress, finding the triple treatment restored photosynthesis, hormone balance, and antioxidant defenses better than any single agent alone.

2025 Journal of Hazardous Materials
Article Tier 2

New Insight on the In Vitro Effects of Melatonin in Preserving Human Sperm Quality

Researchers found that melatonin protects human sperm quality against cadmium-induced oxidative stress in vitro, preserving motility, viability, DNA integrity, and mitochondrial function while reducing lipid peroxidation over 24 hours of exposure.

2022 International Journal of Molecular Sciences 24 citations
Article Tier 2

Exploring the nano-wonders: unveiling the role of Nanoparticles in enhancing salinity and drought tolerance in plants

This review explores how nanoparticles can help plants survive drought and high-salt conditions by protecting cell membranes, boosting photosynthesis, and strengthening antioxidant defenses. While promising for agriculture, the effects of nanoparticles vary depending on their size, shape, and concentration, and their potential toxicity to plants needs further study.

2024 Frontiers in Plant Science 100 citations
Article Tier 2

Melatonin Defends Against the Oxidative Stress by Preventing the Uptake of Nanoplastics and Activating the Antioxidant System in Paeonia ostii.

Scientists found that melatonin (a natural hormone) can protect plants from tiny plastic particles by blocking them from entering plant cells and reducing harmful damage inside the plant. This matters because these microscopic plastics are spreading everywhere in our environment and getting into our food chain. While this study only looked at plants, it suggests melatonin might help protect living things from plastic pollution - though more research is needed to know if this applies to humans.

2026 PubMed
Article Tier 2

Physio-Biochemical Mechanisms of Arbuscular Mycorrhizal Fungi Enhancing Plant Resistance to Abiotic Stress

This review explores how arbuscular mycorrhizal fungi, beneficial soil organisms that form partnerships with plant roots, help crops cope with environmental stresses like drought, salinity, and heavy metal contamination. The fungi improve nutrient uptake, water absorption, and antioxidant defenses while triggering beneficial hormonal responses in host plants. The authors note that wider agricultural use of these fungi is limited by challenges in mass production and variability across different crops and soil conditions.

2024 Agriculture 7 citations
Article Tier 2

High Salinity Stimulates the Adaptive Response to Potassium Deficiency Through the Antioxidant and the NADPH-Generating Systems in the Roots and Leaves of the Halophyte Cakile maritima

Researchers investigated how simultaneous high salinity (400 mM NaCl) and potassium deficiency affect the halophyte Cakile maritima, finding that high salinity stimulates adaptive antioxidant and NADPH-generating responses in roots and leaves that partially compensate for potassium-deficient conditions over 15 days of hydroponic growth.

2022 Journal of Plant Growth Regulation 16 citations
Article Tier 2

Potassium fulvic acid alleviates salt stress of citrus by regulating rhizosphere microbial community, osmotic substances and enzyme activities

This study found that potassium fulvic acid application improved growth of salt-stressed citrus plants by modulating rhizosphere microbial community composition, increasing osmotic adjustment compounds, and enhancing antioxidant enzyme activities, offering a practical soil amendment strategy for salt-affected agricultural land.

2023 Frontiers in Plant Science 23 citations
Article Tier 2

Exogenously Applied Sodium Nitroprusside Alleviated Cadmium Toxicity in Different Aromatic Rice Cultivars by Improving Nitric Oxide Accumulation and Modulating Oxidative Metabolism

Researchers investigated whether spraying sodium nitroprusside, a compound that releases nitric oxide, could help aromatic rice plants cope with cadmium-contaminated soil. They found that the treatment reduced oxidative stress markers in the plants and improved photosynthesis, yield, and grain quality across three rice varieties. The study suggests that nitric oxide supplementation may offer a practical approach for growing rice more safely in heavy metal-polluted agricultural areas.

2024 Agronomy 4 citations