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Showing papers similar to Reduced cellular process and developmental process genotoxicity of polystyrene nanoplastics in zebrafish embryogenesis using Aurelia aurita proteins

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All Human Health Effects 25,424 Gut & Microbiome 6,526 Reproductive & Development 3,270 Food & Water 8,916 Nanoplastics 9,972 Detection Methods 17,548 Remediation 21,169 Marine & Wildlife 30,770 Environmental Sources 38,037 Policy & Risk 19,660
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Article Tier 2

Polystyrene Nanoplastic Exposure Induces Developmental Toxicity by Activating the Oxidative Stress Response and Base Excision Repair Pathway in Zebrafish (Danio rerio)

Researchers exposed zebrafish embryos to polystyrene nanoplastics at various concentrations and found significant developmental abnormalities including reduced hatching rates and increased malformations. The nanoplastics activated oxidative stress responses and DNA repair pathways, indicating cellular damage during critical early development stages. The study provides mechanistic evidence for how nanoplastic exposure can disrupt normal embryonic development in aquatic organisms.

2022 ACS Omega 90 citations
Article Tier 2

Developmental toxicity of functionalized polystyrene microplastics and their inhibitory effects on fin regeneration in zebrafish

Researchers exposed zebrafish to polystyrene microplastics with different surface modifications and found that all types caused developmental toxicity, including increased mortality, reduced body length, and impaired swimming ability. The amino-modified particles were generally the most harmful, also inhibiting fin regeneration after injury. The study suggests that surface chemistry plays a critical role in determining how microplastics interact with biological systems.

2025 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 1 citations
Article Tier 2

Uptake Routes and Biodistribution of Polystyrene Nanoplastics on Zebrafish Larvae and Toxic Effects on Development

Researchers exposed zebrafish embryos and larvae to amino-modified polystyrene nanoplastics to study uptake routes and biodistribution. The study found that nanoplastics accumulated in target organs and caused toxic developmental effects, providing evidence that these tiny plastic fragments can penetrate biological barriers and interfere with normal development in aquatic organisms.

2023 Fishes 17 citations