Papers

61,005 results
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Article Tier 2

Microplastics decrease the toxicity of sulfamethoxazole to marine algae (Skeletonema costatum) at the cellular and molecular levels

Researchers investigated the combined toxicity of the antibiotic sulfamethoxazole and five types of microplastics on the marine alga Skeletonema costatum. They found that certain microplastics actually decreased the toxicity of the antibiotic by adsorbing it, creating a protective "shelter" effect, though polystyrene combined with the antibiotic caused higher oxidative stress. The study suggests that microplastics can alter the bioavailability and toxicity of co-occurring pollutants in marine environments through adsorption interactions.

2022 The Science of The Total Environment 66 citations
Article Tier 2

Behavior of tetracycline and polystyrene nanoparticles in estuaries and their joint toxicity on marine microalgae Skeletonema costatum

Researchers studied the sorption of tetracycline antibiotic onto polystyrene nanoparticles in simulated estuarine conditions and found that the combination was more toxic to the marine diatom Skeletonema costatum than either stressor alone, due to enhanced cellular uptake of antibiotic delivered by nanoplastics.

2020 Environmental Pollution 96 citations
Article Tier 2

Toxic effects of microplastics on extracellular polymeric substances (EPS) in estuarine microalgae under stress conditions

Researchers examined how extracellular polymeric substances (EPS) mediate the response of two estuarine microalgae species — Scenedesmus obliquus and Skeletonema costatum — to polypropylene and polyethylene microplastics. They found species-specific differences, with EPS removal reducing stress tolerance in both species, and S. costatum showing greater photosynthetic regulation capacity under high microplastic concentrations.

2025 Environmental Pollution
Article Tier 2

Joint toxicity of microplastics with triclosan to marine microalgae Skeletonema costatum

Researchers investigated the combined toxicity of triclosan and four types of microplastics on the marine microalga Skeletonema costatum. They found that while all microplastics individually inhibited algal growth, PVC and smaller particles had the strongest effects, and the joint toxicity with triclosan followed an antagonistic pattern rather than additive or synergistic. The study suggests that microplastics can adsorb organic pollutants and partially reduce their bioavailability, though the physical damage from smaller particles remains a significant concern.

2018 Environmental Pollution 337 citations
Article Tier 2

Influences of different functional groups on the toxicity of pyrene derivatives to Skeletonema costatum: Interactive effects with polystyrene microplastics

Researchers examined how polystyrene microplastics modify the toxicity of pyrene and four pyrene derivatives to the marine diatom Skeletonema costatum, finding that functional groups on the pyrene molecule determined whether microplastics enhanced or reduced algal toxicity.

2025 Marine Pollution Bulletin
Article Tier 2

Interplay between extracellular polymeric substances (EPS) from a marine diatom and model nanoplastic through eco-corona formation

Researchers incubated polystyrene nanoplastics with extracellular polymeric substances secreted by a marine diatom and found that these biological molecules rapidly formed an "eco-corona" coating on the nanoparticles, significantly slowing their aggregation and reducing oxidative stress in algae — suggesting that natural organic matter in seawater substantially alters nanoplastic behavior and toxicity.

2020 The Science of The Total Environment 136 citations
Article Tier 2

The Impact of Microplastics on the Growth of Skeletonema Costatum

Researchers exposed the marine diatom Skeletonema costatum to polystyrene microplastics at 0.1 and 10 mg/L, finding that both concentrations initially stimulated cell growth and chlorophyll content but also elevated antioxidant enzyme activity, indicating a stress response even when growth appeared enhanced.

2025 Environment Resource and Ecology Journal
Article Tier 2

The effect of polystyrene plastics on the toxicity of triphenyltin to the marine diatom Skeletonema costatum—influence of plastic particle size

The presence of polystyrene particles of different sizes was found to modify the toxicity of triphenyltin (a toxic organotin compound) to the marine diatom Skeletonema costatum, with effects depending on whether the plastic particles increased or decreased the bioavailability of the chemical. The study illustrates how microplastics can alter the toxicity of co-occurring chemical pollutants to sensitive marine microalgae.

2019 Environmental Science and Pollution Research 40 citations
Article Tier 2

Algal EPS modifies the toxicity potential of the mixture of polystyrene nanoplastics (PSNPs) and triphenyl phosphate in freshwater microalgae Chlorella sp.

Researchers found that a natural substance produced by algae (extracellular polymeric substances, or EPS) can reduce the toxic effects of nanoplastics combined with a flame retardant chemical in freshwater. The EPS coated the nanoplastics and reduced their ability to harm algal cells. This natural protective mechanism could play an important role in how aquatic ecosystems buffer against the combined threat of microplastics and chemical pollutants.

2024 Chemosphere 14 citations
Article Tier 2

Toxicity due to release of microplastic fibres from disposable face masks on marine diatom Chaetoceros sp. and the role of EPS in combating the toxic effects

Researchers studied the toxicity of leachate from disposable face masks on the marine diatom Chaetoceros sp., finding that toxicity increased with longer degradation time. The 21-day mask leachate was the most harmful, with reactive oxygen species production identified as a key toxicity mechanism, while heavy metals were also detected in the leachate. The study found that extracellular polymeric substances produced by the diatoms helped reduce the toxic effects, highlighting a natural defense mechanism against microplastic-related pollution.

2025 Emerging contaminants 1 citations
Article Tier 2

Nanoplastics and their combined effects with sulphamethoxazole on the free-floating aquatic plant Lemna major

Researchers studied the combined effects of polystyrene nanoplastics and the antibiotic sulfamethoxazole on free-floating freshwater organisms, examining how co-exposure to these two pollutants interacts compared to individual exposures. Nanoplastics altered the bioavailability and toxicity of the antibiotic, demonstrating complex mixture effects in aquatic systems.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

The role of algal EPS in reducing the combined toxicity of BPA and polystyrene nanoparticles to the freshwater algae Scenedesmus obliquus

Researchers studied how polystyrene nanoplastics and the industrial chemical BPA affect freshwater algae when combined, and whether the algae's own protective secretions could reduce the damage. Carboxylated nanoplastics were the most toxic form, and the algae's natural exopolymeric substances helped buffer the combined toxicity. The findings suggest that biological interactions in real waterways may partially mitigate some harmful effects of nanoplastic pollution.

2023 Plant Physiology and Biochemistry 42 citations
Article Tier 2

Effects of polystyrene microplastics on the extracellular and intracellular dissolved organic matter released by Skeletonema costatum using a novel in situ method

Researchers studied how polystyrene microplastics affect the dissolved organic matter released by the marine diatom Skeletonema costatum. They found that microplastic exposure altered both the quantity and chemical composition of organic compounds released by the algae, which could in turn influence how other contaminants behave in seawater. The study reveals an indirect pathway through which microplastics may affect marine chemistry and pollutant cycling.

2024 Environmental Pollution 3 citations
Article Tier 2

Synergistic Pollution: Interactions Among Polyethylene, Surfactants, and Antibiotics in an Aquatic Environment

Researchers investigated synergistic pollution effects among polyethylene microplastics, surfactants, and antibiotics in aquatic systems, finding that co-presence enhanced the environmental persistence and bioavailability of antibiotics beyond what microplastics or surfactants caused individually.

2025
Article Tier 2

Investigating the Molecular Response of Skeletonema marinoi to Polyethylene Nano/Microplastics: Insights into Stress Genes, Inflammation, and Extracellular Polymeric Substance Production

Researchers exposed the marine diatom Skeletonema marinoi to polyethylene nano- and microplastics and found that, despite no significant effect on growth, the particles triggered oxidative stress responses, inflammatory-like gene expression, and activation of programmed cell death pathways. The study suggests that even when diatoms appear resilient on the surface, microplastics may cause subtle molecular disruptions that could affect bloom dynamics and carbon cycling in the ocean.

2026 Microplastics
Article Tier 2

Alleviating effects of microplastics together with tetracycline hydrochloride on the physiological stress of Closterium sp.

Researchers studied how PET and PBT microplastics combined with the antibiotic tetracycline affect freshwater microalgae. They found that in some combinations, microplastics actually reduced the toxicity of the antibiotic to the algae, likely by adsorbing the chemical onto their surfaces. The study highlights the complex and sometimes counterintuitive ways that microplastics interact with other pollutants in aquatic environments.

2024 Environmental Science Processes & Impacts 5 citations
Article Tier 2

Combined Effects of Microplastics and Benzo[a]pyrene on the Marine Diatom Chaetoceros muelleri

Researchers investigated the combined effects of microplastics and benzo[a]pyrene on marine diatoms, finding that co-exposure altered toxicity outcomes compared to individual exposures, with effects varying depending on microplastic polymer type and size.

2022 Frontiers in Marine Science 33 citations
Article Tier 2

Preferential adsorption of medium molecular weight proteins in extracellular polymeric substance alleviates toxicity of small-sized microplastics to Skeletonema costatum

Scientists discovered that natural substances secreted by marine algae form a coating on microplastic surfaces that actually reduces the toxicity of the smallest particles. This coating, made of proteins and sugars, changed the surface properties of the microplastics and helped the algae grow better despite the pollution. The finding suggests that natural biological processes in the ocean may partially buffer the harmful effects of microplastics, though this protection may vary with particle size.

2024 Journal of Hazardous Materials 14 citations
Article Tier 2

Inhibitory Effect of Combined Exposure to Copper Ions and Polystyrene Microplastics on the Growth of Skeletonema costatum

Researchers examined how copper ions and polystyrene microplastics individually and together affect the growth of the marine diatom Skeletonema costatum. The study found that microplastics can adsorb copper ions, temporarily reducing copper toxicity to algal cells, but over longer exposure periods the inhibitory effects of microplastics themselves counteracted that benefit.

2024 Water 2 citations
Article Tier 2

Nanoplastics and their combined effects with sulphamethoxazole on the free-floating aquatic plant Lemna major

Researchers examined the combined effects of nanoplastics and the antibiotic sulphamethoxazole on free-floating algae, assessing whether nanoplastics alter antibiotic toxicity. The co-exposure produced greater inhibitory effects on algal growth than either substance alone.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Toxic effects of pristine and aged polystyrene and their leachate on marine microalgae Skeletonema costatum

Researchers compared the toxic effects of pristine and aged polystyrene microplastics, as well as their chemical leachates, on the marine microalga Skeletonema costatum. The study found that aged microplastics and their leachates caused greater growth inhibition, reduced chlorophyll concentration, and triggered stronger oxidative stress responses than pristine particles, suggesting that environmental weathering increases the toxicity of plastic debris.

2022 The Science of The Total Environment 56 citations
Article Tier 2

Interactive toxicity effects of metronidazole, diclofenac, ibuprofen, and differently functionalized nanoplastics on marine algae Chlorella sp.

Researchers examined the combined toxicity of common pharmaceutical drugs and nanoplastics with different surface coatings on marine algae. They found that the interaction between drugs and nanoplastics produced effects ranging from additive to synergistic, depending on the specific combination, with amine-coated nanoplastics generally causing more harm. The study highlights that real-world mixtures of pharmaceutical and plastic pollutants in oceans may pose greater risks to marine life than either contaminant alone.

2025 Environmental Science Processes & Impacts 3 citations
Article Tier 2

Higher toxicity induced by co-exposure of polystyrene microplastics and chloramphenicol to Microcystis aeruginosa: Experimental study and molecular dynamics simulation

Researchers studied what happens when the antibiotic chloramphenicol and polystyrene microplastics are present together in water containing blue-green algae. The study found that the combined exposure was more toxic to the algae than either pollutant alone, disrupting photosynthesis and gene expression. The findings suggest that microplastics and antibiotics may interact in ways that amplify their harmful effects on aquatic ecosystems.

2023 The Science of The Total Environment 38 citations
Article Tier 2

Combined effects of polystyrene nanoplastics and dinophysistoxin-1 (DTX1) on physiological performance of marine diatom Thalassiosira minima

Scientists studied how polystyrene nanoplastics and a marine algal toxin called dinophysistoxin-1 affect a common ocean diatom, both individually and in combination. The nanoplastics alone reduced diatom growth by over 50%, while the toxin reduced it by 22%, but when combined, the nanoplastics actually absorbed some of the toxin and partially offset its effects. The study suggests that nanoplastic pollution in coastal waters creates complex, unpredictable interactions with other marine contaminants that could disrupt the base of the ocean food chain.

2025 Water Research 3 citations