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61,005 resultsShowing papers similar to Effects of fibrous microplastics on the accumulation of tris(2,3-dibromopropyl) isocyanurate and behavior of zebrafish via water- and foodborne exposure routes
ClearFurther negative effect of fibrous microplastics to the bioaccumulation and toxicity of decabromodiphenyl ethane on zebrafish
Researchers investigated how fibrous microplastics from PET plastic interact with a common flame retardant chemical called DBDPE in zebrafish over 28 days. They found that microplastics significantly increased the amount of the flame retardant that accumulated in fish tissue and slowed its elimination from the body. The study suggests that microplastics may act as carriers for other toxic chemicals, amplifying their harmful effects on aquatic organisms.
High accumulation of microplastic fibers in fish hindgut induces an enhancement of triphenyl phosphate hydroxylation
Researchers investigated the role of microplastic fibers — a primary source of textile-derived microplastics — as vectors for triphenyl phosphate flame retardant, using compound spinning for in situ fluorescent measurement and finding that high accumulation of microplastic fibers in zebrafish hindgut significantly enhanced triphenyl phosphate bioaccumulation and hydroxylation metabolism.
Contrasting effects of micro- and nanoplastics on accumulation and toxicity of tris(1,3-dichloro-2-propyl) phosphate in zebrafish embryo revealed by toxicokinetic-toxicodynamic model
Researchers examined how microplastics and nanoplastics differently affect the accumulation and toxicity of the flame retardant TDCIPP in zebrafish embryos. The study found that while microplastics had minimal effect, nanoplastics significantly increased TDCIPP bioaccumulation and enhanced adverse effects on hatching, development, and survival, as validated by toxicokinetic and toxicodynamic modeling.
Toxicities of microplastic fibers and granules on the development of zebrafish embryos and their combined effects with cadmium
Researchers compared the toxicity of polyethylene terephthalate microplastic fibers versus granules on zebrafish embryo development, and examined their combined effects with cadmium. They found that fibrous microplastics caused more severe developmental abnormalities than granular particles, and both forms enhanced cadmium toxicity when present together. The study suggests that microplastic shape is an important factor in toxicity assessments and that fiber-shaped particles may pose greater risks to aquatic organisms.
The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish
Researchers investigated how different polymer types of microplastics affect the toxicity and bioaccumulation of the antimicrobial chemical triclosan in zebrafish. They found that polypropylene microplastics had the highest capacity to adsorb triclosan and that co-exposure significantly worsened oxidative stress, lipid damage, and neurotoxicity compared to triclosan alone. The study demonstrates that the type of microplastic polymer matters when assessing the combined environmental risks of plastics and chemical pollutants.
Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the “Trojan horse” effect a matter of concern?
Researchers tested whether microplastic ingestion increases the bioconcentration of hydrophobic organic chemicals in zebrafish, examining the so-called 'Trojan horse' effect. They found that exposure to contaminated polyethylene microplastics did not significantly increase chemical accumulation in fish compared to waterborne exposure alone. The study suggests that for these chemicals, direct water exposure remains the dominant uptake pathway, and the microplastic carrier effect may be less concerning than previously thought.
Effects of microplastics on the accumulation and neurotoxicity of methylmercury in zebrafish larvae
Researchers found that microplastics can adsorb methylmercury and act as carriers, increasing its accumulation in zebrafish larvae and worsening neurotoxicity by disrupting locomotor activity and triggering oxidative stress.
Neurobehavioral and neurochemical effects of nano-sized polypropylene accumulation in zebrafish (Danio rerio)
Researchers exposed zebrafish to polypropylene nanoparticles and confirmed the particles accumulated in brain tissue using advanced imaging and chemical analysis. The accumulation led to measurable neurotoxic effects, including reduced movement activity and disrupted neurotransmitter levels. The study suggests that nanoscale polypropylene, one of the most commonly produced plastics, may pose risks to nervous system function in aquatic organisms.
Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics
Co-exposure of zebrafish to triphenyl phosphate (TPhP) with micro- or nano-polystyrene showed that nano-PS (46 nm) aggravated TPhP-induced liver and gonad enlargement, while micro-PS had minimal effect — suggesting nanoplastics can enhance the toxicity of organophosphate flame retardants.
Effects of pristine or contaminated polyethylene microplastics on zebrafish development
Researchers examined the effects of both pristine and pollutant-contaminated polyethylene microplastics on zebrafish development through chronic exposure. The study assessed how microplastics, both alone and as carriers of adsorbed organic pollutants, affect developing fish. The findings provide new insights into how contaminated microplastics may create additional routes for toxic compounds to enter aquatic food webs.
Effects of Microplastics and Nanoplastics on Neurodevelopment and Neurodegeneration in Zebrafish
This review covers how micro- and nanoplastic (MNP) exposure affects neurodevelopment and neurodegeneration in zebrafish, summarising evidence on impaired neurodevelopment, behavioural changes, and markers of neurodegeneration from studies using various polymer types and exposure routes. It frames zebrafish as a key model for understanding MNP neurotoxicity.
Accumulation of different shapes of microplastics initiates intestinal injury and gut microbiota dysbiosis in the gut of zebrafish
Researchers exposed zebrafish to three different shapes of microplastics and found that fibers and fragments accumulated more in the gut than beads, causing greater intestinal injury and disruption of gut bacteria. The shape of the microplastic particles significantly influenced both how much accumulated and the severity of the biological harm. The study suggests that microplastic shape is an important factor in assessing their environmental and health risks.
Sorbed environmental contaminants increase the harmful effects of microplastics in adult zebrafish, Danio rerio
Researchers found that microplastics carrying sorbed environmental contaminants (DDE, BP-3, chlorpyrifos) caused greater harmful effects on adult zebrafish health and behavior than pristine microplastics alone, demonstrating their role as pollutant vectors.
The significance of trophic transfer of microplastics in the accumulation of plastic additives in fish: An experimental study using brominated flame retardants and UV stabilizers
Researchers found that trophic transfer through food is a more significant route than direct water exposure for fish accumulation of plastic-derived chemicals, including brominated flame retardants and UV stabilizers associated with microplastics.
From particle size to brain function: a zebrafish-based review of micro/nanoplastic-induced neurobehavioral toxicity and mechanistic pathways
This review uses zebrafish as a model to examine how micro- and nanoplastics cause neurobehavioral toxicity, linking particle size to brain function disruption. Researchers summarize evidence that these plastic particles impair fish behavior and cause molecular-level damage in the nervous system. The findings highlight the growing concern that micro- and nanoplastics are emerging neurotoxicants in aquatic environments.
Determination of Bisphenol Compounds and the Bioaccumulation after Co-Exposure with Polyethylene Microplastics in Zebrafish
Researchers developed a method to measure how bisphenol A and bisphenol S accumulate in zebrafish tissues when microplastics are also present. They found that microplastics increased the accumulation of these hormone-disrupting chemicals in fish tissues, with BPA building up more than BPS. The evidence indicates that microplastics can act as carriers that enhance the uptake of harmful chemicals by aquatic organisms.
Effects on Zebrafish of Chemical Contaminants and Additives Present in Microplastics
Researchers fed zebrafish for 60 days on diets containing 10% environmental microplastics collected from beaches in Lanzarote and Tenerife, alongside clean pellet and control groups, then analyzed chemical contaminants in tissues by liquid chromatography coupled to high-resolution mass spectrometry. Results confirmed bioaccumulation of plastic additives and chemical contaminants in zebrafish tissues over time, with plastic synthesizers reaching the highest tissue concentrations followed by plasticizers.
Aging relieves the promotion effects of polyamide microplastics on parental transfer and developmental toxicity of TDCIPP to zebrafish offspring
Researchers discovered that pristine polyamide microplastics promoted the transfer of the flame retardant TDCIPP from parent zebrafish to offspring and increased developmental toxicity, but aging of the microplastics reduced these harmful effects due to changed surface properties.
Accumulation and Distribution of Fluorescent Microplastics in the Early Life Stages of Zebrafish
Researchers tracked the accumulation and distribution of fluorescent microplastics in early life stages of a freshwater organism, finding that microplastics were taken up and distributed across body tissues. The results help explain how microplastics accumulate in young aquatic organisms and potentially affect their development.
Rethinking the relevance of microplastics as vector for anthropogenic contaminants: Adsorption of toxicants to microplastics during exposure in a highly polluted stream - Analytical quantification and assessment of toxic effects in zebrafish (Danio rerio)
Researchers exposed microplastics in a highly polluted stream to assess their role as contaminant vectors, then tested effects on zebrafish, finding that naturally contaminated microplastics had limited additional toxicity compared to the polluted water itself.
Nanoplastics Cause Neurobehavioral Impairments, Reproductive and Oxidative Damages, and Biomarker Responses in Zebrafish: Throwing up Alarms of Wide Spread Health Risk of Exposure
Researchers exposed adult zebrafish to polystyrene nanoplastics and found that the particles accumulated in the brain, liver, intestine, and gonads, causing significant behavioral and physiological changes. The fish showed disrupted energy metabolism, oxidative stress, and altered locomotion, aggression, and predator avoidance behaviors. The findings raise concerns about the widespread health risks of nanoplastic exposure, as these particles are small enough to cross biological membranes.
Microplastics Lead to Hyperactive Swimming Behaviour in Adult Zebrafish
Researchers exposed adult zebrafish to polystyrene microplastics across a wide concentration range and found that microplastics accumulated primarily in the gastrointestinal tract and gills. The study revealed that exposed fish exhibited hyperactive swimming behavior, suggesting that microplastic ingestion can affect locomotor activity even without obvious physical damage to internal organs.
Leaching of polybrominated diphenyl ethers from microplastics in fish oil: Kinetics and bioaccumulation
The leaching kinetics of polybrominated diphenyl ethers (PBDEs) from microplastics into fish oil were characterized to estimate chemical transfer to organism tissues upon ingestion. Leaching rates were contaminant- and polymer-dependent, providing mechanistic data for assessing how ingested microplastics increase exposure to inherent flame retardant additives.
Nanoplastics transport in zebrafish brain: Molecular and phenotypic behavioral impacts
This study tracked how nanoplastics of two sizes (50 nm and 200 nm) accumulate in and clear from zebrafish brains. Smaller nanoplastics built up more and lasted longer in the brain, causing greater damage to neurons and more behavioral changes like reduced activity and impaired learning. The findings suggest that the tiniest plastic particles may pose the most risk to brain health because they are harder for the body to remove.