Papers

20 results
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Article Tier 2

Two genes related to reproductive development in the juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Nanoplastic exposure altered the expression of two genes involved in reproductive development in juvenile freshwater prawns (Macrobrachium nipponense), suggesting that nanoplastics may disrupt reproductive pathways in crustaceans at low concentrations.

2021 Chemosphere 17 citations
Article Tier 2

Polystyrene nanoplastics decrease molting and induce oxidative stress in adult Macrobrachium nipponense

Researchers found that polystyrene nanoplastics significantly decreased molting frequency and induced oxidative stress in adult freshwater prawns, with effects on antioxidant enzyme activities observed at environmentally relevant concentrations.

2022 Fish & Shellfish Immunology 37 citations
Article Tier 2

Polystyrene nanoplastics induce apoptosis, histopathological damage, and glutathione metabolism disorder in the intestine of juvenile East Asian river prawns (Macrobrachium nipponense)

Researchers exposed juvenile East Asian river prawns to different concentrations of polystyrene nanoplastics for 28 days. They found that nanoplastic exposure caused intestinal cell death, tissue damage, and disrupted the glutathione antioxidant system in a dose-dependent manner. The study suggests that nanoplastic pollution in freshwater environments could significantly compromise the intestinal health and immune defenses of crustaceans.

2024 The Science of The Total Environment 5 citations
Article Tier 2

Polystyrene nanoplastics inhibit reproduction and induce abnormal embryonic development in the freshwater crustacean Daphnia galeata

Researchers exposed the freshwater crustacean Daphnia galeata to polystyrene nanoparticles and observed significant decreases in survival, reproduction, and embryonic development. Using fluorescence microscopy, they tracked the particles as they transferred from external body surfaces to internal organs including the ovaries and brood chamber. The study also found that exposed adults had fewer and smaller lipid droplets, suggesting that nanoplastics disrupt energy storage and reproductive capacity in these organisms.

2017 Scientific Reports 247 citations
Article Tier 2

Effects of nanoplastics on energy metabolism in the oriental river prawn (Macrobrachium nipponense)

Oriental river prawns exposed to polystyrene nanoplastics (5–40 mg/L) for up to 28 days showed concentration- and time-dependent decreases in survival and energy metabolism, including disrupted glycogen and triglyceride content, reduced metabolic enzyme activity, and altered gene expression of energy pathways.

2020 Environmental Pollution 110 citations
Article Tier 2

From gonads to generations: Mechanistic insights into reproductive disruption by polystyrene nanoplastics and co-contaminants in fish

This review synthesizes current research on how polystyrene nanoplastics impair reproductive health in fish, including disruption of gonad structure, hormone levels, and gene regulation along the reproductive axis. Researchers found that nanoplastics can cause oxidative stress and inflammation in reproductive tissues and may even affect offspring development. The findings raise concerns about the long-term effects of nanoplastic pollution on fish populations and aquatic ecosystem health.

2025 Environmental Chemistry and Ecotoxicology 3 citations
Article Tier 2

Chronic exposure to polystyrene microplastics at environmentally relevant concentration induced growth retardation in Macrobrachium rosenbergii via multi-pathway toxicity: Oxidative stress, microbial dysbiosis, and biodistribution

Researchers exposed juvenile freshwater prawns to environmentally relevant concentrations of polystyrene microplastics for 42 days and found significant growth inhibition, with a 15.6% reduction in body length and 29.6% decrease in body weight. The microplastics accumulated in gills, stomachs, intestines, and hemolymph, causing persistent mitochondrial damage, oxidative stress, and gut microbiota imbalance that did not fully recover even after the exposure ended.

2026 Environmental Pollution
Article Tier 2

Polystyrene microplastics induced male reproductive toxicity and transgenerational effects in freshwater prawn

Researchers found that polystyrene microplastics caused significant reproductive harm in male freshwater prawns, including oxidative stress in testis tissue, hormonal imbalances, and reduced sperm quality. Notably, the offspring of exposed prawns also showed reduced survival and weakened immunity even when they were not directly exposed to microplastics. The study reveals that microplastic exposure can produce transgenerational effects in aquatic organisms, passing harm from parents to offspring.

2022 The Science of The Total Environment 85 citations
Article Tier 2

Effects of nanoplastic exposure on the growth performance and molecular characterization of growth-associated genes in juvenile Macrobrachium nipponense

Researchers found that polystyrene nanoplastic exposure impaired growth in juvenile shrimp by damaging the hepatopancreas, disrupting digestive enzyme activity, and altering growth-related gene expression at concentrations above 10 mg/L.

2022 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 22 citations
Article Tier 2

Effects of nanoplastics on antioxidant and immune enzyme activities and related gene expression in juvenile Macrobrachium nipponense

Researchers explored the effects of nanoplastics on survival, antioxidant activity, immune enzyme activity, and gene expression in juvenile oriental river prawns. The study found that increasing nanoplastic concentrations suppressed antioxidant and immune enzyme activities while altering related gene expression levels, indicating that nanoplastic exposure can compromise the defense systems of freshwater crustaceans.

2020 Journal of Hazardous Materials 195 citations
Article Tier 2

Short-term polystyrene nanoplastic exposure alters zebrafish male and female germline and reproductive outcomes, unveiling pollutant-impacted molecular pathways

A short 96-hour exposure to polystyrene nanoplastics harmed both male and female reproductive cells in zebrafish. In males, nanoplastics crossed the testicular barrier, entered reproductive cells directly, and caused abnormal sperm with reduced movement. In females, the exposure disrupted egg development, suggesting that even brief nanoplastic contact could impair fertility in aquatic species and raising questions about similar risks for human reproductive health.

2024 Journal of Hazardous Materials 13 citations
Article Tier 2

Change in energy-consuming strategy, nucleolar metabolism and physical defense in Macrobrachium rosenbergii after acute and chronic polystyrene nanoparticles exposure

Researchers examined how polystyrene nanoplastic exposure affects freshwater prawns over both short-term and long-term periods, finding significant changes in gene expression related to energy metabolism and physical defense. The study revealed that nanoplastic exposure disrupted nucleolar metabolism and triggered shifts in energy-consuming strategies, suggesting these particles pose a meaningful threat to aquatic crustaceans.

2023 Aquatic Toxicology 12 citations
Article Tier 2

Impacts of Environmental Concentrations of Nanoplastics on Zebrafish Neurobehavior and Reproductive Toxicity

Researchers exposed zebrafish to environmentally realistic levels of polystyrene nanoplastics and found they caused both brain and reproductive damage. The nanoplastics disrupted neurotransmitter signaling and impaired the hormonal pathway connecting the brain to reproductive organs, with different effects in males and females. These findings suggest that even low-level nanoplastic exposure could affect both brain function and fertility in aquatic life that humans may consume.

2024 Toxics 16 citations
Article Tier 2

Polystyrene Nanoplastics Disrupt Hepatic Vitellogenin Metabolism and Impair the Reproduction Process in Female Zebrafish

Researchers exposed female zebrafish to polystyrene nanoplastics and found that the particles disrupted the production of vitellogenin, a key protein involved in egg development. Higher concentrations led to reduced reproductive output and changes in liver function. The study suggests that nanoplastic pollution in waterways could interfere with fish reproduction by disrupting the hormonal and metabolic pathways essential for egg formation.

2024 Annals of Animal Science 9 citations
Article Tier 2

Polystyrene nanoplastic exposure induces immobilization, reproduction, and stress defense in the freshwater cladoceran Daphnia pulex

Researchers documented how polystyrene nanoplastics accumulate in the guts of the freshwater crustacean Daphnia pulex and cause chronic toxicity at environmentally relevant concentrations, delaying reproduction, reducing offspring numbers, and inducing then suppressing antioxidant defense genes over a 21-day exposure.

2018 Chemosphere 285 citations
Article Tier 2

Effects of Microplastics, Polystyrene, and Polyethylene on Antioxidants, Metabolic Enzymes, HSP-70, and Myostatin Expressions in the Giant River Prawn Macrobrachium rosenbergii: Impact on Survival and Growth

Researchers exposed juvenile giant river prawns (Macrobrachium rosenbergii) to polystyrene microspheres and polyethylene microparticles and found that both types reduced survival and growth while increasing oxidative stress markers and altering expression of heat shock proteins and myostatin, with polystyrene causing more severe effects.

2021 Archives of Environmental Contamination and Toxicology 34 citations
Article Tier 2

Ingestion and bioaccumulation of polystyrene nanoplastics and their effects on the microalgal feeding of Artemia franciscana

Brine shrimp (Artemia franciscana) exposed to polystyrene nanoplastics ingested and bioaccumulated the particles, which also affected their feeding behavior on microalgae and caused changes in gut microbiota. These effects on a widely used aquaculture species raise concerns about nanoplastic contamination in marine food production.

2019 Ecotoxicology and Environmental Safety 59 citations
Article Tier 2

Female zebrafish (Danio rerio) exposure to polystyrene nanoplastics induces reproductive toxicity in mother and their offspring

Researchers exposed female zebrafish to polystyrene nanoplastics for six weeks and found the particles disrupted sex hormone levels and oocyte development, reducing egg production in the exposed generation and carrying endocrine disruption effects into unexposed offspring through the hypothalamic-pituitary-gonadal axis.

2024 Aquatic Toxicology 21 citations
Article Tier 2

Sublethal Effects of Polystyrene Nanoplastics on the Embryonic Development of Artemia salina (Linnaeus, 1758)

Researchers exposed brine shrimp embryos to amino-modified polystyrene nanoplastics of two sizes and assessed a range of developmental effects. They found that the nanoplastics accumulated in the organisms and caused sublethal effects including altered hatching rates and developmental abnormalities, even at non-lethal concentrations. The study suggests that nanoplastic pollution may pose risks to the early development of organisms at the base of aquatic food chains.

2023 Animals 15 citations
Article Tier 2

Chronic effects of nano and microplastics on reproduction and development of marine copepod Tigriopus japonicus

Researchers studied the chronic effects of polystyrene nano- and microplastics on the marine copepod Tigriopus japonicus over 30 days. The study found that nanoplastics were more lethal than microplastics, with different sizes affecting survival, development, and reproduction through distinct mechanisms, though oxidative stress was a common factor at high concentrations.

2022 Ecotoxicology and Environmental Safety 44 citations