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61,005 resultsShowing papers similar to Are microplastics in food a risk factor for obesity: Current evidence, mechanistic pathways and emerging health risks associated with human exposure
ClearIs There Evidence of Health Risks From Exposure to Micro- and Nanoplastics in Foods?
This review examines the evidence for health risks from micro- and nanoplastic exposure through food, noting that plastic particles can carry physical, chemical, and biological hazards. The study suggests that ingested plastics could contribute to inflammation, oxidative stress, and immune responses, and may even influence food allergy development by altering gut permeability and intestinal microbiome balance.
Human exposure to micro- and nanoplastics: a mechanistic perspective of health risks associated with metabolic and reproductive functions
This review examines how micro- and nanoplastics enter the human body through food, air, and skin contact, and the mechanisms by which they may disrupt metabolic and reproductive health. Researchers describe how these particles are absorbed through the gut, enter the bloodstream, and accumulate in organs where they can trigger inflammation, oxidative stress, and hormonal disruption. The evidence indicates that micro- and nanoplastics, particularly those carrying endocrine-disrupting chemicals, may pose significant risks to fertility and metabolic function.
Eco-toxicity of nano-plastics and its implication on human metabolism: Current and future perspective
This review examines the sources, bioaccumulation pathways, and potential health effects of nanoplastics on human metabolism. Researchers found that nanoplastics can enter the body primarily through ingestion of contaminated food and packaging, and evidence suggests they may interfere with metabolic pathways and contribute to organ dysfunction. The study highlights that significant knowledge gaps remain in assessing the human health risks of nanoplastic exposure.
Biological exposure to microplastics and nanoplastics and plastic additives: impairment of glycolipid metabolism and adverse effects on metabolic diseases
This review examines how exposure to micro- and nanoplastics disrupts the body's ability to process sugars and fats, potentially contributing to diabetes, obesity, and atherosclerosis. The plastics cause inflammation and oxidative stress, damage gut bacteria, trigger insulin resistance, and increase fat buildup in the liver. For people who already have metabolic conditions, plastic exposure may make their disease worse.
Source, migration path and pollution of microplastics and nano-plastics in food
This review traced the sources, migration pathways, and food contamination status of microplastics and nanoplastics, covering their entry into food chains through packaging, processing, environmental pollution, and water sources—and discussing potential accumulation in the human body and associated health risks.
Exploring the micro- and nanoplastics–diabetes nexus: Shattered barriers, toxic links, and methodological horizons
This review examines growing evidence that micro- and nanoplastics may contribute to diabetes by disrupting blood sugar regulation, insulin signaling, and fat metabolism through oxidative stress and inflammation. Animal studies show that plastic particles can damage the pancreas, liver, and gut in ways that mirror the development of diabetes, though human studies are still limited. The review calls for more research into whether everyday microplastic exposure could be a hidden factor in the global rise of metabolic diseases.
Potential risk assessment and toxicological impacts of nano/micro-plastics on human health through food products
This review examined the potential risks and toxicological effects of nano- and microplastics on human health through food products, identifying key contamination sources in the food chain and their harmful impacts on the body.
Impact of Microplastic Exposure on Human Health: A Systematic Review of Mechanisms, Biomarkers, and Clinical Outcomes
This systematic review found that microplastics have been detected in human blood, placental tissue, and gastrointestinal samples, with proposed health mechanisms including oxidative stress, chronic inflammation, endocrine disruption, and gut microbiome alterations. While direct clinical evidence remains limited, the accumulating laboratory and observational data point to microplastics as a plausible contributor to multiple disease pathways.
Cellular mechanisms of microplastic and nanoparticle exposure and its relationship with metabolic diseases: Literature review
This literature review examined how microplastic and nanoparticle exposure affects cellular mechanisms related to metabolic disease, finding evidence that these contaminants disrupt insulin signaling, alter lipid metabolism, and may contribute to the development of metabolic syndrome.
Untoward Effects of Micro- and Nanoplastics: An Expert Review of Their Biological Impact and Epigenetic Effects
This expert review examined the biological and epigenetic effects of micro- and nanoplastics on living organisms. The study suggests that while intestinal uptake of plastic particles appears relatively low and size-dependent, nanoplastics may dysregulate molecular signaling pathways, alter gut microbiota composition, and induce transgenerational epigenetic changes potentially linked to metabolic disorders.
Growing concerns over ingested microplastics in humans
This paper reviews the growing body of evidence showing that microplastics have been found in various human tissues, raising public health concerns. Researchers note that while laboratory studies demonstrate microplastics can cause cellular damage, significant knowledge gaps remain regarding dose-response relationships, specific target organs, and underlying toxicological mechanisms. The study calls for improved detection technologies and thorough risk assessments to better understand the real-world health implications.
Microplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence
This review examines the growing body of evidence on how microplastics enter the human body through ingestion, inhalation, and skin contact, and have now been detected in blood, lung tissue, placenta, and cardiovascular tissue. Evidence indicates that microplastics may cause harm through oxidative stress, inflammation, and cellular damage, though a direct causal link to specific health conditions has not yet been fully established.
Microplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence
This review examines the growing body of evidence on how microplastics enter the human body through ingestion, inhalation, and skin contact, and have now been detected in blood, lung tissue, placenta, and cardiovascular tissue. Evidence indicates that microplastics may cause harm through oxidative stress, inflammation, and cellular damage, though a direct causal link to specific health conditions has not yet been fully established.
Potential Health Impact of Environmentally Released Micro- and Nanoplastics in the Human Food Production Chain: Experiences from Nanotoxicology
This review assesses the potential for micro- and nanoplastics to enter the human food chain, drawing on evidence from studies of food production and related biological systems. Researchers found that while larger microplastics are unlikely to be absorbed by the human body, nanoplastics may be small enough to cross biological barriers and accumulate in tissues. The study highlights that much remains unknown about real-world human exposure levels and calls for more research into the health implications of these tiny particles in food.
Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects
This review examines the biological mechanisms by which micro- and nanoplastics may cause harm in humans, including oxidative stress, inflammation, disruption of protective barriers, and immune system problems. Evidence from lab and animal studies suggests these particles can affect the gut, heart, brain, and reproductive systems, though human data is still limited to detecting plastics in tissues rather than proving they cause specific diseases. The authors highlight that most studies use higher doses than people actually encounter, making it important to develop research models that better reflect real-world chronic exposure.
Microplastic pollution: A potent threat for metabolic disruption in mammals
This review examines the evidence linking microplastic exposure to metabolic disruption, covering mechanisms by which microplastics and their associated chemical additives may interfere with hormonal regulation, glucose metabolism, and lipid homeostasis. The authors identify microplastics as a potent emerging threat to metabolic health.
Micro- and nano-plastic contamination in foods and potential risk to human health
This review summarizes the current state of knowledge about micro- and nanoplastic contamination in food, covering sources, occurrence, and analytical detection methods. Researchers found that while various foods, especially seafood, contain measurable levels of microplastics, the health risks to humans remain difficult to assess due to inconsistent research methods. The study calls for standardized approaches to better evaluate dietary exposure and potential health impacts.
Effects of food contact material-related nanoplastics on 3T3-L1 cell uptake and lipid metabolism
Researchers examined the uptake of food contact material-derived nanoplastics into 3T3-L1 adipocyte cells and assessed subsequent effects on lipid metabolism. The study investigated how nanoplastics that migrate from packaging into food may disrupt fat storage and metabolic signaling at the cellular level.
Recent advances in toxicological research and potential health impact of microplastics and nanoplastics in vivo
This review summarizes the growing body of research on how micro- and nanoplastics affect living organisms, covering impacts from physical tissue damage and gut disruption to reproductive harm and immune system interference. Researchers found that these tiny particles can also act as carriers for heavy metals, toxic chemicals, and pathogens, potentially amplifying their harmful effects. The evidence indicates that microplastics may move up the food chain and ultimately reach humans, though the full extent of health risks remains under investigation.
Adverse Outcome Phenomena and Toxicity Mechanisms of Micro and Nanoplastics in Human Health
This review examines the growing evidence that micro- and nanoplastics can enter the human body through food, water, and air, and may contribute to harmful biological effects. Researchers found that these tiny particles can trigger oxidative stress, inflammation, and disruption of hormonal and immune systems in laboratory studies. The study highlights the need for a unified research approach to better understand how microplastic exposure may affect long-term human health.
Effect of micro- and nanoplastics as food contaminants on the immune system
This review synthesized research on how microplastic and nanoplastic exposure affects immune system function, finding evidence across multiple studies that these particles can modulate immune responses and trigger inflammatory pathways in exposed organisms. The authors highlight immune disruption as an emerging health concern from micro- and nanoplastic contamination.
A Review of Human Exposure to Microplastics and Insights Into Microplastics as Obesogens
This review examines how humans are exposed to microplastics through air, dust, water, food, and even baby bottles, with estimated intake ranging from tens of thousands to millions of particles per year. Emerging evidence suggests that microplastics may act as obesogens, meaning they could disrupt fat metabolism and hormonal systems through chemical additives like phthalates and bisphenols. The review raises particular concern about infant exposure, as babies may face higher levels of microplastics from plastic feeding bottles and medical devices.
Human Exposure to Microplastics and Its Associated Health Risks
This review examines how microplastics enter the human body through food, air, and skin, and have been detected in stool, blood, and tissues. Research in lab animals and human cells shows that microplastics can disrupt digestion, immunity, the nervous system, and reproduction, and can also amplify the toxicity of other environmental pollutants they carry.
Micro- and nanoplastics: Emerging environmental threats to the Developmental Origins of Health and Disease
This review examines how micro- and nanoplastic exposure may contribute to chronic health conditions through the lens of developmental origins of health and disease. Evidence suggests that microplastics accumulate in human metabolic and reproductive tissues and may induce physiological and epigenetic changes that could potentially be inherited by future generations, though research into these mechanisms is still in early stages.