Papers

61,005 results
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Article Tier 2

How predicted temperature and salinity changes will modulate the impacts induced by terbium in bivalves?

This study investigated how changing ocean salinity and temperature affect the toxicity of terbium, a rare earth metal from electronic waste, in mussels. Climate change conditions like decreased salinity and increased temperature worsened the toxic effects, including damage to the nervous system and increased cell death. While focused on terbium, the findings are relevant because microplastics can absorb and carry rare earth metals, and changing ocean conditions may amplify the toxicity of pollutants that hitch a ride on microplastic surfaces.

2024 Chemosphere 14 citations
Article Tier 2

Global climate change increases the impact of pollutant mixtures in the model species Paracentrotus lividus

Researchers found that ocean acidification and warming conditions predicted for the next 50 years significantly increased the toxicity of chlorpyrifos and microplastics on sea urchin fertilization and larval development, suggesting climate change will amplify the impact of pollutant mixtures on marine organisms.

2023 The Science of The Total Environment 8 citations
Article Tier 2

Developmental and biochemical markers of the impact of pollutant mixtures under the effect of Global Climate Change

Researchers studied how microplastics combined with the pesticide Chlorpyriphos affect sea urchin larvae under simulated ocean warming and acidification conditions. They found that the combination of these stressors caused significant developmental abnormalities and signs of oxidative stress in the larvae. The study suggests that the real-world cocktail of pollutants and climate change may be more harmful to marine life than any single stressor alone.

2024 Chemosphere 4 citations
Article Tier 2

Will temperature rise change the biochemical alterations induced in Mytilus galloprovincialis by cerium oxide nanoparticles and mercury?

Researchers exposed mussels (Mytilus galloprovincialis) to cerium oxide nanoparticles and mercury alone and in combination at current and elevated temperatures, finding that mercury caused the most significant metabolic damage, CeO2 nanoparticles partially counteracted mercury's effects, and elevated temperature overrode both — highlighting that climate warming may amplify toxicological impacts in coastal marine organisms.

2020 Environmental Research 59 citations
Article Tier 2

Combined effect of microplastics and global warming factors on early growth and development of the sea urchin (Paracentrotus lividus)

Researchers studied the combined effects of microplastics, ocean acidification, and temperature increase on sea urchin larval development. Microplastics alone reduced larval growth by about 20%, but when combined with lowered pH, growth inhibition was significantly greater and morphological abnormalities appeared. The study demonstrates that microplastic pollution can compound the effects of climate change stressors on marine organisms during their most vulnerable developmental stages.

2021 The Science of The Total Environment 60 citations
Article Tier 2

Development of metal adaptation in a tropical marine zooplankton

Researchers exposed a tropical marine copepod (a tiny crustacean key to ocean food chains) to copper pollution across seven generations, finding that while the animals developed increased tolerance over time, they became significantly more vulnerable to heat stress — suggesting that pollution-adapted species may be less equipped to handle climate change.

2020 Scientific Reports 23 citations
Article Tier 2

Interactive Immunomodulation in the Mediterranean Mussel Mytilus galloprovincialis Under Thermal Stress and Cadmium Exposure

Combined exposure to elevated temperature and cadmium in Mediterranean mussels triggered complex interactive effects on immune and antioxidant systems, with simultaneous stressors producing non-additive responses that highlight the difficulty of predicting organism health in multiply polluted warming seas.

2021 Frontiers in Marine Science 18 citations
Article Tier 2

Does Thermal Stress Modulate the Biochemical and Physiological Responses of Ruditapes Decussatus Exposed to the Progestin Levonorgestrel?

Researchers studied how combined exposure to warming temperatures and the synthetic hormone levonorgestrel (found in contraceptives) affects clams. Both stressors together caused greater disruption to the clam's biochemistry and physiology than either alone. This suggests climate warming may amplify the harm that pharmaceutical pollutants cause to marine shellfish.

2021 Research Square (Research Square)
Article Tier 2

Oysters under anthropogenic pressure: A cellular perspective on the interactive effects of microplastic pollution and climate change

Researchers exposed oysters to microplastics under combined conditions of elevated temperature and ocean acidification, finding that climate change stressors significantly altered the cellular response to MP pollution. Temperature had a stronger effect than acidification, and combined stressors produced non-additive interactions in immune and oxidative stress markers.

2025 Media (https://www.suub.uni-bremen.de/)
Article Tier 2

The effect of climate change and microplastics on the physiology of marine invertebrates of economic interest

This thesis examines how climate change and microplastic pollution interact to affect the physiology of marine invertebrates important for aquaculture. Combined stressors were found to have compounding effects on organisms like mussels and oysters, threatening both ecosystems and food security.

2023 LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Article Tier 2

Each temperature degree counts: warming enhances polystyrene nanoplastic toxicity via metabolic disruption in a marine cellular model

This study examined how elevated water temperatures — simulating marine heatwaves — amplify the toxicity of polystyrene nanoplastics in marine cells, finding that warming enhanced metabolic disruption caused by nanoplastics. The results suggest climate change and plastic pollution interact synergistically to harm marine organisms.

2025 Aquatic Toxicology
Article Tier 2

Impact of microplastics and ocean acidification on critical stages of sea urchin (Paracentrotus lividus) early development

Researchers investigated the combined effects of microplastic pollution and ocean acidification on sea urchin early development, finding that acidified conditions amplified microplastic toxicity, disrupting fertilization, embryo development, and larval growth in Paracentrotus lividus.

2022 Chemosphere 24 citations
Article Tier 2

Molecular markers of stress in the sea urchin embryo test: Analysing the effect of climate change and pollutant mixtures on Paracentrotus lividus larvae

This study exposed sea urchin larvae to future ocean conditions (warming and acidification) combined with chlorpyrifos-contaminated microplastics and used RNA sequencing to assess responses. Combined stressors caused significant transcriptional shifts in metabolic, cellular, and developmental pathways, with morphological effects including reduced larval size.

2025 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology
Article Tier 2

Polymer aging affects the bioavailability of microplastics-associated contaminants in sea urchin embryos

Researchers found that UV aging of microplastics alters the bioavailability of co-contaminants like flame retardants and metals to sea urchin embryos, with combined exposures generating transcriptional responses distinct from single-contaminant effects.

2022 Chemosphere 22 citations
Article Tier 2

Combined effects of global warming and microplastic exposure from individual to populational levels of a benthic copepod

This study assessed the combined effects of global warming and microplastic exposure on freshwater and marine organisms across individual and population levels, examining how climate and plastic pollution interact as co-occurring stressors. Results showed that warming conditions modified microplastic toxicity in ways that suggest climate change will alter the ecological risk of plastic pollution in aquatic systems.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Research progress in ecotoxicology of climate change coupled with marine pollutions

This review examined how rising ocean temperatures and acidification from climate change interact with marine pollutants including microplastics, finding that combined stressors often produce worse effects than either alone. The research underscores that plastic pollution cannot be addressed in isolation from the broader context of global climate change.

2017 Chinese Science Bulletin (Chinese Version) 2 citations
Article Tier 2

Responses of Mytilus galloprovincialis in a Multi-Stressor Scenario: Effects of an Invasive Seaweed Exudate and Microplastic Pollution under Ocean Warming

Researchers exposed mussels to a combination of invasive seaweed exudate, polyethylene microplastics, and elevated temperatures to study their combined effects. The study found that simultaneous exposure to all three stressors greatly reduced byssal thread production and depleted antioxidant defenses in gill tissue, suggesting that multiple environmental stressors can amplify harmful effects on marine organisms.

2023 Toxics 9 citations
Article Tier 2

Biochemical and Behavioural Alterations Induced by Arsenic and Temperature in Hediste Diversicolor of Different Growth Stages

Researchers found that arsenic exposure combined with elevated water temperature produced synergistic biochemical and behavioral toxicity effects in the polychaete Hediste diversicolor across different life stages, suggesting that climate change may amplify the harmful impacts of heavy metal contamination in marine invertebrates.

2022 Preprints.org 4 citations
Article Tier 2

The effects of microplastic ingestion and environmental warming on camouflage and growth in common shore crabs

Researchers found that shore crabs exposed to both microplastics and warming water showed impaired camouflage ability and reduced growth compared to crabs exposed to either stressor alone. The combined effects of microplastic pollution and climate change may be more harmful to marine life than either threat in isolation.

2021 Open Research Exeter (University of Exeter) 1 citations
Meta Analysis Tier 1

Meta-analysis reveals temperature increase exacerbates microplastic toxicity in freshwater invertebrates

This meta-analysis pools data from multiple studies to show that rising temperatures make microplastics more toxic to freshwater invertebrates. The combined stress of warming water and plastic pollution caused greater harm to growth, reproduction, and survival than either stressor alone, suggesting that climate change will worsen the ecological and health impacts of microplastic contamination.

2025 Environmental Sciences Europe 1 citations
Article Tier 2

The combined effects of polystyrene microplastics and temperature stress on Mytilus galloprovincialis, Lamarck, 1819

Researchers investigated the combined effects of polystyrene microplastics and rising water temperatures on Mediterranean mussels. The study found that microplastic exposure amplified temperature-related stress, leading to increased mortality, greater oxidative damage, and more severe tissue changes, suggesting that these two environmental stressors interact to worsen harm to marine organisms.

2026 Marine Pollution Bulletin
Article Tier 2

Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium

Researchers examined how sea cucumbers respond to polystyrene microplastics, cadmium, and their combination over an extended exposure period. They found that combined exposure caused more severe effects on growth, immune function, and oxidative stress than either stressor alone, and that the animals activated specific molecular defense pathways. The study reveals that the interaction between microplastics and heavy metals in marine environments can create compounding stress on commercially and ecologically important species.

2024 Marine Pollution Bulletin 6 citations
Article Tier 2

Environmental pharmaceuticals and climate change: The case study of carbamazepine in M. galloprovincialis under ocean acidification scenario

Researchers exposed mussels simultaneously to the common pharmaceutical carbamazepine and simulated ocean acidification, finding that the combination caused greater cellular damage and immune disruption than either stressor alone. The study highlights how ocean acidification — driven by rising CO₂ — may amplify the toxicity of pharmaceutical pollutants in marine shellfish.

2020 Environment International 55 citations
Article Tier 2

Nano-ecotoxicology in a changing ocean

Researchers reviewed how ocean warming, acidification, and chemical co-contaminants interact with nanomaterial pollution in marine environments, finding that these combined stressors often alter how toxic nanoparticles behave in seawater — sometimes making them more dangerous and sometimes less — highlighting the need to study pollutants in realistic, multi-stressor conditions.

2022 SN Applied Sciences 13 citations