Papers

61,005 results
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Article Tier 2

Polystyrene microplastics disrupted physical barriers, microbiota composition and immune responses in the cecum of developmental Japanese quails

Researchers fed Japanese quails environmentally relevant concentrations of polystyrene microplastics for five weeks and examined their gut health. They found that microplastics damaged the physical barriers of the cecum, disrupted the gut microbial community, and impaired immune responses. The study suggests that even low-level microplastic contamination in the environment could compromise gut health and immune function in birds.

2023 Journal of Environmental Sciences 25 citations
Article Tier 2

Environmental Microplastic Exposure Changes Gut Microbiota in Chickens

Researchers exposed chickens to environmentally relevant concentrations of microplastics and found that their growth performance decreased significantly. The gut microbiota composition was also altered, with changes in the abundance of several bacterial groups important for digestion and health. The study suggests that microplastic contamination in poultry environments could affect both animal welfare and the broader food production chain.

2023 Animals 20 citations
Article Tier 2

Environmental microplastics exposure decreases antioxidant ability, perturbs gut microbial homeostasis and metabolism in chicken

Researchers studied the effects of microplastic exposure on chickens and found that it decreased growth performance and antioxidant capacity while causing damage to the intestine, liver, kidney, and spleen. The study also revealed significant changes in gut microbiota composition, including decreased diversity and shifts in taxonomic makeup, suggesting microplastics disrupt gut microbial homeostasis in poultry.

2022 The Science of The Total Environment 77 citations
Article Tier 2

The impact of polyethylene microplastics exposure on the, growth performance, reproductive performance, antioxidant capacity, and intestinal microbiota of quails

Researchers fed quails different levels of polyethylene microplastics and found that exposure harmed their growth, reproduction, and gut health. The microplastics reduced antioxidant defenses and disrupted the balance of beneficial bacteria in the birds' intestines. Since poultry is a major food source for people, microplastic contamination in farm animals raises concerns about indirect human exposure through the food chain.

2025 Ecotoxicology and Environmental Safety 6 citations
Article Tier 2

Microplastics: a potential threat to gut microbiota and antioxidant capacity of broiler chickens

Researchers investigated the effects of microplastic exposure on broiler chickens and found significant increases in liver enzyme and oxidative stress markers alongside decreased antioxidant capacity. The study also revealed substantial disruption to gut microbiota, with reduced diversity and altered microbial community structure affecting energy metabolism, amino acid metabolism, and other key functions.

2026 Frontiers in Microbiology
Article Tier 2

Exposure to microplastics affects fatty acid composition in the Japanese quail depending on sex and particle size

Researchers exposed Japanese quail to microplastics and found that the effects on fatty acid composition varied depending on both the sex of the bird and the size of the plastic particles. The study suggests that microplastic ingestion may disrupt lipid metabolism in birds, with potential implications for their health and reproductive fitness.

2023 The Science of The Total Environment 10 citations
Article Tier 2

Gut dysbiosis: Nutritional causes and risk prevention in poultry, with reference to other animals

This review examines the causes and consequences of gut dysbiosis in poultry and other animals, identifying microplastics as one of several environmental pollutants that can disrupt gastrointestinal microbial communities. Researchers describe how reduced microbial diversity leads to inflammation, compromised gut barriers, and disorders affecting multiple organ systems. The study highlights that microplastics, along with heavy metals, pesticides, and other contaminants, contribute to the growing challenge of maintaining healthy gut microbiomes in animal populations.

2025 South African Journal of Animal Science 1 citations
Article Tier 2

Impact of microplastics on human gut microbiota: first evidences from in vitro gut models

Researchers investigated the impact of microplastics on human gut microbiota using in vitro gut models, providing early experimental evidence of how microplastic exposure may disrupt intestinal microbial communities. The study offers foundational data on microplastic-microbiome interactions that are difficult to study directly in humans.

2022 HAL (Le Centre pour la Communication Scientifique Directe)
Article Tier 2

Review: interactions between microplastics and the gastrointestinal microbiome

This review summarizes existing research on how microplastics interact with the gut microbiome in humans, mice, chickens, and aquatic animals. Evidence suggests that gut bacteria can break microplastics into smaller pieces, which may make them more likely to cross the intestinal wall and enter the body. The disruption of the gut microbiome by microplastics is particularly concerning because balanced gut bacteria are essential for immune function, digestion, and overall health.

2024 Italian Journal of Animal Science 14 citations
Article Tier 2

Microplastics as an aquatic pollutant affect gut microbiota within aquatic animals

This review examined how microplastics affect the gut microbiota of aquatic animals, analyzing the roles of plastic-associated chemicals and biofilms in disrupting microbial communities from ingestion through physiological impacts.

2021 Journal of Hazardous Materials 109 citations
Article Tier 2

Impacts of microplastics exposure on mussel (Mytilus edulis) gut microbiota

Researchers exposed marine mussels (Mytilus edulis) to microplastics and analyzed changes to their gut microbiota, finding significant shifts in microbial community composition that could affect digestion, immunity, and overall health.

2020 The Science of The Total Environment 111 citations
Article Tier 2

Microplastics-gut microbiota interactions in an in vitro model of the toddler colon

Researchers used an in vitro model of the toddler colon to investigate how microplastics interact with the gut microbiota in young children. The study examined changes in microbial community composition and metabolic activity following microplastic exposure, providing early evidence of potential disruption to the developing gut ecosystem.

2025 SPIRE - Sciences Po Institutional REpository
Meta Analysis Tier 1

The impact of microplastics on the mice gut microbiome: a meta-analysis

This meta-analysis pools data from multiple mouse studies to assess how ingested microplastics affect gut bacteria. It found that microplastic exposure can alter the balance of the gut microbiome, which is important because gut health is closely tied to immune function, digestion, and overall well-being.

2025
Article Tier 2

Ecotoxicological impacts of microplastics to gut microbiota: Response mechanism, challenges and environmental sustainability-A review

This review summarizes how microplastics affect gut bacteria in fish, mice, and earthworms after being swallowed. Microplastics can change the balance of gut microbes and reduce their helpful functions, leading to digestive problems, slower growth, and weakened immunity. Since humans are exposed to microplastics through food and water, these findings raise concerns that our own gut health could be similarly affected.

2025 Ecotoxicology and Environmental Safety 5 citations
Article Tier 2

Microplastics and the gut microbiome: How chronically exposed species may suffer from gut dysbiosis

This review explores how chronic microplastic exposure may disrupt the natural balance of gut bacteria in wildlife, a condition known as dysbiosis. Researchers suggest that ingesting microplastics can cause mechanical damage to the gastrointestinal tract, introduce foreign bacteria, and deliver chemical additives that disturb gut microbial communities. The study highlights that microplastic-induced gut dysbiosis could weaken immune systems, promote infections, and contribute to chronic health issues in exposed species.

2019 Marine Pollution Bulletin 338 citations
Article Tier 2

Exposure to High-molecular-weight Polyvinyl Chloride Alters Bacterial Diversity in the Gut Microbiota of the Wistar Rat

Researchers exposed Wistar rats to high-molecular-weight polyvinyl chloride microplastics through their diet and measured changes in gut microbiota diversity and composition. PVC microplastic ingestion significantly altered bacterial diversity in the gut microbiome, supporting the hypothesis that microplastic exposure can disrupt intestinal microbial ecology with potential consequences for host health.

2024 Rocznik Ochrona Środowiska
Article Tier 2

Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice

Researchers fed mice different concentrations of polyethylene microplastics for five weeks and found significant changes in gut bacteria composition and signs of intestinal inflammation. Higher doses increased bacterial diversity and altered the balance of specific bacterial species, while triggering immune responses and inflammation in the colon and duodenum. The study provides evidence that microplastic ingestion can disrupt the gut microbiome and promote intestinal inflammation in mammals.

2019 Chemosphere 626 citations
Article Tier 2

In vivo exposure of mixed microplastic particles in mice and its impacts on the murine gut microbiome and metabolome

Researchers exposed mice to a mixture of common microplastic types to investigate effects on the gut microbiome and metabolome. The study found that ingested microplastic particles altered gut microbial composition and disrupted metabolic pathways, suggesting that realistic mixed-microplastic exposure may have broader biological effects than single-polymer studies indicate.

2025 Toxicological Sciences 1 citations
Article Tier 2

Effects of polystyrene microplastics on the composition of the microbiome and metabolism in larval zebrafish

Researchers exposed larval zebrafish to two sizes of polystyrene microplastics and found significant changes in gut microbiome composition and metabolic activity. The microplastics altered the abundance and diversity of gut bacteria and disrupted metabolic pathways important for development. The study suggests that early-life exposure to microplastics could have meaningful biological consequences by reshaping the gut environment of developing organisms.

2018 Chemosphere 472 citations
Article Tier 2

Gut Check: Microbiota and Obesity in Mice Exposed to Polystyrene Microspheres

Researchers found that gut microbiota appeared to play a mediating role in the obesity outcomes observed in mice fed manufactured polystyrene microspheres, suggesting that microplastic-induced alterations to the gut microbiome may be a mechanism linking microplastic exposure to metabolic dysfunction and weight gain.

2024 Environmental Health Perspectives
Article Tier 2

Microplastic Ingestion Induces Size-Specific Effects in Japanese Quail

Researchers found that Japanese quail ingesting environmentally collected microplastics showed size-specific effects, with small particles under 125 micrometers causing different physiological responses than larger 3mm particles, demonstrating that particle size matters for avian microplastic toxicity.

2022 Environmental Science & Technology 37 citations
Article Tier 2

Toxicological Evaluation of Effects of Some Environmental Pollutants on Intestinal Microbiota: Traditional Review

This review examines how various environmental pollutants affect the gut microbiome — the community of microorganisms in the intestinal tract. Microplastics are among the pollutants discussed, and their ability to alter gut microbiota composition is increasingly recognized as a mechanism by which plastic particles may harm human and animal health.

2023 Journal of Literature Pharmacy Sciences
Article Tier 2

Current levels of microplastic pollution impact wild seabird gut microbiomes

Researchers studied wild seabirds and found that the amount of microplastics in their guts was linked to significant changes in their gut bacteria. Birds with more microplastics had fewer beneficial bacteria and more harmful ones, including disease-causing and antibiotic-resistant species. This is one of the first studies to show that real-world microplastic exposure is already altering gut microbiomes in wild animals.

2023 Nature Ecology & Evolution 139 citations
Article Tier 2

Effects of frying on microplastics load in fish and implications on health

Researchers investigated the effects of polyethylene microplastics on gut microbiota composition in mice fed a high-fat diet, finding that microplastic exposure altered microbial diversity and increased gut permeability. Co-exposure with a high-fat diet amplified metabolic disruption.

2022 Food Frontiers 9 citations